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Membrane proteins of arterivirus particles: Structure, topology, processing and function

Virus Research, 2014
Arteriviruses, such as equine arteritis virus (EAV) and porcine reproductive and respiratory syndrome virus (PRRSV), are important pathogens in veterinary medicine. Despite their limited genome size, arterivirus particles contain a multitude of membrane proteins, the Gp5/M and the Gp2/3/4 complex, the small and hydrophobic E protein and the ORF5a ...
Michael Veit, Anna Karolina Matczuk
exaly   +3 more sources

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Arterivirus PRRSV

1998
Pigs were infected with the porcine respiratory and reproductive syndrome virus (PRRSV) by the oronasal route. We studied the development of histological lesions, sites of virus infection and of inflammatory infiltrates by quantitative evaluation of reactive cells. The animals developed a multifocal interstitial pneumonia.
J, Beyer, D, Fichtner, H, Schirrmeier, H, Granzow, U, Polster, E, Weiland, A, Berndt, H, Wege   +7 more
openaire   +2 more sources

Arterivirus Minor Envelope Proteins Are a Major Determinant of Viral Tropism in Cell Culture [PDF]

Journal of Virology, 2012
ABSTRACT Arteriviruses are enveloped positive-strand RNA viruses for which the attachment proteins and cellular receptors have remained largely controversial. Arterivirus particles contain at least eight envelope proteins, an unusually large number among RNA viruses.
Debin Tian, Zuzhang Wei, Guang-zhi Tong
exaly   +4 more sources

IFN-αTreatment Enhances Porcine Arterivirus Infection of Monocytes via Upregulation of the Porcine Arterivirus Receptor Sialoadhesin

Journal of Interferon & Cytokine Research, 2007
The Arterivirus porcine reproductive and respiratory syndrome virus (PRRSV) has a specific tropism for a subset of differentiated macrophages. Porcine sialoadhesin was identified as a PRRSV internalization receptor that is, similarly to sialoadhesins from other species, only expressed on subsets of macrophages.
P L, Delputte, W, Van Breedam, F, Barbé, K, Van Reeth, H J, Nauwynck   +4 more
openaire   +2 more sources

Arterivirus Pathogenesis and Immune Response

2014
The family Arteriviridae within the order Nidovirales includes a single genus, Arterivirus. Equine arteritis virus (EAV) is the type species of the genus, and the three other currently known members are lactate dehydrogenase-elevating virus (LDV), porcine reproductive and respiratory syndrome virus (PRRSV), and simian hemorrhagic fever virus (SHFV ...
N. James MacLachlan, Udeni B. Balasuriya, Michael P. Murtaugh, Stephen W. Barthold, Linda J. Lowenstine   +4 more
openaire   +1 more source

Suppression of porcine arterivirus replication by baculovirus-delivered shRNA targeting nucleoprotein

Biochemical and Biophysical Research Communications, 2006
The ability to synthesize shRNAs from DNA templates driven by RNA polymerase III promoters has made it possible to apply virus-derived vectors as delivery vehicles for double-strand RNA-mediated interference. Baculovirus emerges as a promising vector for in vivo gene therapy most recently.
Lu, L., Ho, Y., Kwang, J.
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Arterivirus Structural Proteins and Assembly

2014
This chapter reviews the structural characteristics of the Arteriviridae, including the basic molecular details of all of the proteins involved, the interactions of these proteins and where they occur, and further functional characterization. The arterivirus structural proteins discussed are E protein, glycoprotein 2, glycoprotein 3, glycoprotein 4 ...
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Functional analysis of the porcine USP18 and its role during porcine arterivirus replication

Gene, 2009
Emerging evidence places deubiquitylation at the core of a multitude of regulatory processes, ranging from cell growth to innate immune response and health, such as cancer, degenerative and infectious diseases. Little is known about deubiquitylation in pig and arterivirus infection.
Tahar, Ait-Ali, Alison W, Wilson, Heather, Finlayson, Wilfrid, Carré, Sreenivasa Chakravarthy, Ramaiahgari, David G, Westcott, Martin, Waterfall, Jean-Pierre, Frossard, Kwang-Hyun, Baek, Trevor W, Drew, Stephen C, Bishop, Alan L, Archibald   +11 more
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Arterivirus

2009
Fil: Echeverria, Maria Gabriela. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Departamento de Microbiología. Cátedra de Virología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas.
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[Molecular and biological aspects of Arterivirus].

Virologie (Montrouge, France)
Arteriviruses are a group of small enveloped viruses with a genome composed of a positive, single-stranded, 5'-capped and 3'-polyadenylated RNA molecule. These viruses belong to the Arteriviridae family which together with the Coronaviridae and Roniviridae families constitutes the order Nidovirales.
E, Roques, W, Saron, S, Peiro, D, Archambault   +3 more
openaire   +1 more source