Results 41 to 50 of about 1,473,438 (312)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Anomalous right pulmonary artery from the aorta [PDF]

, 2006
Anomalous origin of the right pulmonary artery is a rare form of congenital heart disease. It usually presents in early infancy with heart failure and rapid development of pulmonary hypertension. There are about 131 cases reported in the literature and
Wong, Abdul Rahim, Rasool, Aida Hanum Ghulam, Mokhtar, S.A.I.   +2 more
core  

Robot assisted Internal Mammary Artery detection for coronary revascularisation surgery [PDF]

, 2010
This paper presents a semi-automatic robotic system supporting a surgeon in the harvesting of the internal mammary artery (IMA) for an open chested intervention in coronary revascularisation surgery.
Vazquez, Adrian, Hirzinger, Gerd, Florian A Fröhlich, Passig, Georg, Georg Passig, Gerd Hirzinger, Adrian Vazquez, Fröhlich, Florian A.   +7 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

An interpretable machine learning model for predicting stroke in patients with hypertension: insights from the SPRINT

Scientific Reports
Stroke is a leading cause of mortality worldwide, with hypertension being its most significant risk factor. However, few studies have specifically developed predictive models for stroke risk in hypertensive patients with elevated cardiovascular risk ...
Jiayi Han, Li Lin, Tengxiao Zhao, Yang Zhang, Zehao Zhao, Wenjie Wang, Ruixiang Feng, Yaodong Ding, Yong Zeng   +8 more
doaj   +1 more source

Arterial Calcification Increases in Distal Arteries in Patients with Peripheral Arterial Disease [PDF]

Annals of Vascular Surgery, 2008
The aim of this study was to determine if significant differences in plaque composition exist between the popliteal and tibial vessels in patients with severe peripheral arterial disease (PAD). Forty-four patients with PAD required either above-knee (n = 38), below-knee (n = 5), or through-knee (n = 1) amputation for pedal sepsis/gangrene.
Paul D, Bishop, Lindsay E, Feiten, Kenneth, Ouriel, Sean P, Nassoiy, Mircea L, Pavkov, Daniel G, Clair, Vikram S, Kashyap   +6 more
openaire   +2 more sources

Coronary artery grafting in infants [PDF]

, 2009
Coronary artery bypass grafting (CABG) with cardiac vale repair is an uncommon surgery in infants. CABG is technically demanding in infants due to the small size not only of the coronary arteries but also the potential graft arteries.
Menon, Rajgopal, Zacharias, S., Maskari, Salim, Valliathu, J.   +3 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Cardiovascular Risk Factors: A Study on the Prevalence of MS among 11-18 Years Old School Children in East of Iran, 2012

Nutrition and Food Sciences Research, 2015
Background and Objectives: Metabolic syndrome (MS) is associated with increased risk of cardiovascular disorders. MS is increasing among adolescents. This study was conducted to determine the prevalence of MS in 11-18 years old Birjandi school children ...
Fatemeh Taheri, Kokab Namakin, Mahmoud Zardast, Tayeb Chakandi, Tooba Kazemi, Bita Bijari   +5 more
doaj  

Impact of obstructive sleep apnea on prognosis of patients with cardiometabolic multimorbidity

Diabetology & Metabolic Syndrome
Background Cardiometabolic multimorbidity (CMM) is a growing global health problem, and obstructive sleep apnea (OSA) is recognized as an important risk factor for cardiovascular disease.
Xiaogang Liu, Siyi Li, Xiao Wang, Jingyao Fan, Wei Gong, Yan Yan, Hui Ai, Bin Que, Wen Zheng, Shaoping Nie   +9 more
doaj   +1 more source