Results 51 to 60 of about 1,597,366 (264)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang +8 morewiley +1 more sourceA complicated case of renal artery stenosis [PDF]
, 2005 This article presents a boy with bilateral renal artery stenosis who presented with severe
hypertension and haemorrhagic stroke. The diagnostic workup along with a
complication of eventual surgical intervention are demonstrated.peer ...Chetcuti-Ganado, C., Samuel, Anthony, Grech, Victor E. +2 morecore Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia +15 morewiley +1 more sourceCarotid artery disease screening : assessment of criteria [PDF]
, 1996 The Department of Radiology at St. Luke’s Hospital has provided a screening service for stroke related disease since April 1991. This consisted of Duplex Ultrasound screening (DUS) for Extracranial Carotid Artery Disease (ECAD) followed by angiography or Galea Debono, Anthony, Zammit, Anthony, Gatt, Alexander +2 morecore UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši +2 morewiley +1 more sourceMetabolic syndrome increases the risk of significant coronary artery involvement in patients with peripheral artery disease
, 2006 Background Peripheral artery disease is a common condition, mainly associated with clinical cardiovascular risk factors. Patients with peripheral artery disease suffer from coronary artery disease-related complications.Biyikoglu, Senay Funda, YILMAZ, MEHMET BİRHAN, Guray, Yesim, Tandogan, Izzet, Korkmaz, Sule, Guray, Umit +5 morecore +1 more sourceCarotid artery stenting compared with endarterectomy in patients with symptomatic carotid stenosis (International Carotid Stenting Study): an interim analysis of a randomised controlled trial [PDF]
, 2010 Background Stents are an alternative treatment to carotid endarterectomy for symptomatic carotid stenosis, but previous trials have not established equivalent safety and efficacy.McFarland, R., Davies, S., Verhelst, R., Gimenez Gaibar, A., Saunder, A., McCabe, D. J. H., Grigg, M., Morgan, R., Barber, P.A., Porras, M, Naylor, R., Lo, T.H., Giroux, M.F., Paananen, T., Hamilton, G., van Sambeek, M. R. H. M., Rose, J., Yan, B., van Hasselt, B.A.A.M., de Kort, G. A. P., Treurniet, F., Obach, V., Ijas, P., Kaste, M., Macho, J., Hudion, M., Blankensteijn, J. D., Milosevic, Z., San Roman, L., Symth, J. V., van der Kallen, B.F.W., Featherstone, Roland L., Roos, Y. B. W. E. M., et al., Featherstone, R.F., Halloul, Z., Brown, Martin M., Milne, P., Walker, S., Lelek, M., van der Lugt, A., Dixit, S. A., de Leeuw, F.E., Kall, T.B., Kapelle, L. J., Brennan, A., Fell, G., Jayakrishnan, V., Soulez, G., Bladin, C., Kobayashi, A., de Borst, Gert J., Wetznel, S., Guta, R., Tindall, H., Bower, S., Moss, J., Beasley, A., Nieholt, G.J.L.A., Czepiel, W., Borst, G.J. de, Gett, S., Stary, D., Cloud, G., MacKay, A.J., Czlonkowska, A., Bruininckx, C.M.A., Berg, B., Railo, M., Bamford, J., Dobson, J., Caron, J. L., Ruchat, P., Brooks, M., Roy, D., Nasim, A., Gottsäter, Anders,, Malmstedt, A., Thornton, J., Nair, R., Gould, D. A., Seriki, D. M., de Bruijn, S. F., Smyth, J.V., Hendriks, J. M. H., Mccabe, D.J.H., Hirt, L., Thompson, A., McGuire, A.J., Radue, E-W, McCabe, D., Cheshire, N., van der Worp, H. Bart, Bourchier, R., Zeilstra, D. J., Ederle, Joerg, Van Schil, P., Dobson, Joanna, Brookes, J., Hammady, M., Vehmas, A., Scriven, J.M., O'Neill, P., Kirsch, E., Quinn, J., Ederle, J., Vanhooren, G., Macdonald, S., Pereira, A., Adiseshiah, M., Gottsäter, Anders, Moll, F., Koelemay, M.J.W., Lepantalo, M., Nederkoorn, Paul J, McGahan, T., Sztajzel, R., Björses, Katarina, Chataway, J., Koelemay, M. J. W., Reekers, J.A.A., Thornton, M., Dorman, P. J., Nassef, A., O'Neill, P., Mas, J. L., van Sambeek, L.R.H.M., Atkinson, N., Kool, L.J.S., van den Berg, J.S.P., Blair, J.F., Golkar, A., Skalej, M., van Otterloo, J.C.A.D., van der Kallen, B. F. W., Hill, A., Walker, M. G., Binaghi, S., Pattynama, P. M. T., Thomas, D., Thomson, G., Sandler, D., Malmstedt, J., Leeuw, F.E. de, Gannon, M., MacKay, A. J., Lebrun, L-H, Leggett, D., Prakash, K. G., Verbist, J., Edwards, R.D., Roberts, N., Bonati, LH, van den Berg, J. S. P., Konrad, P., Markus, H., Brennan, P., Verhagen, H., Nieholt, G. J. Lycklama A., Woodruff, P., Dixit, S.A., Verhargen, H.J.M., Enevoldson, T.P., Bonati, L. H., Engelter, S. T., Koudstaal, P. J., Chu, P., Dorman, Paul J., Lo, T. Hauw, Vliet, J.A. van der, Kirbis, J., Dorman, PJ, Halliday, A., Hendriks, Johanna M, Collins, R., Krohg-Sorensen, K., Soinne, L., Takolander, R., Ray, M., Jedrzejewska, J., Shinton, R.A., Serracino-Inglott, F., Gaines, P., van der Vliet, J.A., Venables, G., Ford, G., Rodgers, H., Verhagen, H. J. M., de Bruijn, S.F., Nederkoorn, P.J., McCollum, Charles, Lees, T., Ivancev, Krassi,, Ivancev, K., Brown, Martin M, Dunbabin, D., Hammer, F., van Dijk, L.C., Deloose, K., Bakke, S. J., Giroux, M-F, Crowe, P., Daneault, N., Algra, A., Platts, A., Brew, S., Puutala, J., Leahy, A., d'Archambeau, O., Daneault, M., Blasco, J., Schultz, D., New, G., Gillgren, P., Mitchell, P., Kitchen, N., Walker, M.G., Jenkins, M., Fluri, F., Mas, J.L., Than, P.G., Beiles, B., Hill, M., McWilliams, R. G., Ghekiere, J., Worp, H.B. van der, Wilmink, T., Bosiers, M., Porras, M., van Overhagen, H., Holden, A., Polanski, J., Michel, P., Caron, J.L., Gaibar, A.G., Bradbury, A., Bell, J., Oliva, V., Estela, J., Featherstone, R. L., Kirkpatrick, P. J., Nederkoorn, Paul J., van Urk, H., Scriven, J. M., Warlow, C., Hendriks, J. M., Gould, D.A., Brown, M.M., McCollum, C., Dowzenko, A., Astarci, P., Higgins, N., Jackson, R., Bishop, C., Roos, Y.B.W.E.M., Than, P. G., Clifton, A., Bonvin, C., Lyrer, P.A., Jaeger, R., Clifford, C., van Dijk, L., Kelly, C., Jones, L., DeJaegher, L., Sidhu, P., Wong, A., Kapelle, L.J., Stewart, J., Beard, J., Radue, E.W., Martin, P., Molynewc, A., Hendriks, Johanna M., Murith, N., Barber, P. A., Mätzsch, Thomas, Pattynama, P.M.T., Macdonald, S, Cras, P., Hu, W., Adam, D., Davis, N., Stanley, B., de Borst, G. J., Vasco, J., Lyrer, Philippe A., Mustanoja, S., Devos, V., Featherstone, R. F., Donnan, G., Boiten, J., Lebrun, L.H., Wetzel, S., Gilling-Smith, G., Field, P., Lo, TH, Nasser, H-C, Davis, M., Foreman, R., Nawaz, S., McGuire, A. J., Seriki, D.M., Ivancev, Krassi, Wahlgren, N., Maetzsch, T., Wong, J., Allard, B., Tennoe, B., Chamorro, A., Baker, D., Roberts, A., Mendelow, A. D., Dobson, J, Clark, D., Cleveland, T., d'Archambeau, O., Lund University., Engelter, S.T., van der Worp, H Bart, Bonati, Leo H., Mitchell, D., Bjorses, K., Reekers, J. A. A., Cambell, W., Tress, B., Lambert, D., Bland, M., Wasner, M., Knippenberg, B., de Borst, Gert J, de Vries, A. C., Featherstone, RL, Lo, T. H., Canovas, D., Peeters, A., Riambau, V., Nederkoorn, P. J., de Kort, G.A.P., Harno, H., de Beer, F.C., Skjelland, M., Ruefenacht, D., Munro, E., Blankensteijn, J.D., Putaala, J., Lees, K.R., Nyman, N., International Carotid Stenting Study investigators, Keunen, R., Jager, R., Belli, A., De Letter, J., Sairanen, T., Lyrer, P. A., Goertler, M., Soderman, M., de Vries, A.C., Mosch, A., Kirkpatrick, P.J., Schultze Kool, L.J., Hoare, M., Ashleigh, R., Baldwin, N., Punekar, S., Dyker, A., Bradbury, A. W., Koudstaal, P.J., Dodd, D., Harris, P. L., Guerke, L., Moroney, J., Kalangos, A., Gibbs, R., Dorman, Paul J, Gaines, Peter, Bruininckx, C. M. A., Stierli, P., Henderson, M.J., Wahlgren, C., Estela, Jordi, Zvan, B., Clarke, M., Bonati, Leo H, Lyrer, Philippe A, Edwards, R. D., Björses, Katarina,, Mätzsch, Thomas,, Shinton, R. A., van Dijk, L. C., Wyatt, M., Lacroix, V., Ederle, Jörg, Branera, J., Holt, M., Tibballs, J., Gaines, P, van der Worp, H. B., Lanthier, S., Enevoldson, T. P., Biejat, Z., Hacke, W., Bradbury, A.W., van Otterloo, J. C. A. de Mol, Featherstone, Roland L, Peters, A., Gottsater, A., Scroop, R., White, R., Wever, J., Sonesson, B., Ferro, J. M., Alback, A., Lovblad, K., Lo, T Hauw, Ederle, J, Wolfe, J., Jacob, A.L., Baker, T., Bell, R., Molan, M., Kool, L. J. Schultze, Raymond, J., Ferro, J.M., Kall, T-B, Sonesson, Björn,, Weill, A., Perendreu, J., Coward, L., Bonati, L.H., Henderson, M. J., Brown, M. M., Morrish, W., Louw, S., Mali, W.P.T.M., Lees, K. R., Rogers, P., Nasser, H.C., Sutherland, G., Harris, P.L., van Hasselt, B. A. A. M., van der Vliet, J. A., Zeilstra, D.J., Blair, J-F, Formgren, J., de Borst, G.J., Vikatmaa, P., Wallis, A., Hendriks, J.M., Chambers, B., Delle, M., Bakke, S.J., Bialek, P., Stansby, G., Prakash, K.G., Butterfield, S., D'Souza, S., van der Worp, H.B., Mendelow, A.D., McWilliams, R.G., Dewey, H., D'Souza, S., Mali, W. P. Th M., Andersson, T., Dolman, P., Lonsdale, R., de Beer, F. C., Egun, A., Chong, W., Guilbert, F., Gamble, G. E., Jacob, A. L., Dorman, P.J., Chan, A., van Buggenhout, E., Subramanian, G., Featherstone, R.L., De Leeuw, F. E., Macdonald, Sumaira, Gamble, G.E., Malik, I., Sonesson, Björn, de, Borst GJ, van, der Worp HB +483 morecore +1 more sourcePrognostic implications of obstructive sleep apnea in patients with unstable angina stratified by remnant cholesterol and triglyceride: a prospective cohort study
BMC Cardiovascular DisordersBackground The prognostic significance of obstructive sleep apnea (OSA) in patients with unstable angina (UA) based on remnant cholesterol (RC) or triglyceride (TG) levels remains unclear.Yun Zhou, Wei Gong, Yan Yan, Xiao Wang, Wen Zheng, Bin Que, Siyi Li, Zekun Zhang, Xiuhuan Chen, Jingyao Fan, Wenlong Zhao, Qingjie Xin, Hui Ai, Shaoping Nie +13 moredoaj +1 more sourceBasement membrane collagen IV deficiency promotes abdominal aortic aneurysm formation
Scientific Reports, 2021 Abdominal aortic aneurysm (AAA) is a complex disease which is incompletely accounted for. Basement membrane (BM) Collagen IV (COL4A1/A2) is abundant in the artery wall, and several lines of evidence indicate a protective role of baseline COL4A1/A2 in AAA L. B. Steffensen, J. Stubbe, J. S. Lindholt, H. C. Beck, M. Overgaard, M. Bloksgaard, F. Genovese, S. Holm Nielsen, M. L. T. Tha, S. K. Bang-Moeller, M. K. T. Hong Lin, J. H. Larsen, D. R. Hansen, G. T. Jones, M. J. Bown, M. A. Karsdal, L. M. Rasmussen +16 moredoaj +1 more source
