Objectives Exposures in utero and during infancy may impact the development of diseases later in life. They may be linked with development of frailty, although the mechanism is unclear.
Terence W O'Neill +5 more
doaj +1 more source
Visualization and phenotyping of proinflammatory antigen-specific T cells during collagen-induced arthritis in a mouse with a fixed collagen type II-specific transgenic T-cell receptor beta-chain [PDF]
Introduction: The Vbeta12-transgenic mouse was previously generated to investigate the role of antigen-specific T cells in collagen-induced arthritis (CIA), an animal model for rheumatoid arthritis. This mouse expresses a transgenic collagen type II (CII)
Burkhardt, H +23 more
core +1 more source
Results of treatment methods in the long term of experimental septic arthritis
The effects of synovectomy on joint cartilage destruction were investigated by late term experimental septic arthritis in 30 New Zeland rabbits. Antibiotic treatment was begun on the sixth day after staphylococcus aureus inoculation in to the knee joint ...
Murat Gurun +3 more
doaj
The selective inhibition of the Syk tyrosine kinase ameliorates experimental autoimmune arthritis
Autoimmune arthritis – such as rheumatoid arthritis – affect a significant proportion of the population, which can cause everyday joint pain, decreased mobility and reduced quality of life.
Eszter Káposztás +11 more
doaj +1 more source
The role of eicosanoids in experimental Lyme arthritis
Experimental Lyme arthritis is an inflammatory arthritis caused by infection of mice with the spirochete, Borrelia burgdorferi. It recapitulates many of the disease parameters seen in human patients with Lyme arthritis, and thus serves as a model system ...
Charles Robert Brown +1 more
doaj +1 more source
Exacerbation of symptomatic arthritis by cigarette smoke in experimental arthritis.
IntroductionEpidemiologically, cigarette smoking is a well-known risk factor for the pathogenesis of rheumatoid arthritis (RA). However, there has been few plausible explanations why cigarette smoking aggravated RA.
Jaewoo Kang +6 more
doaj +1 more source
Liposomal targeting of prednisolone phosphate to synovial lining macrophages during experimental arthritis inhibits M1 activation but does not favor M2 differentiation. [PDF]
BACKGROUND: To determine the effects of liposomal targeting of prednisolone phosphate (Lip-PLP) to synovial lining macrophages on M1 and M2 polarization in vitro and during experimental arthritis. MATERIAL AND METHODS: Experimental arthritis (antigen and
Wouter Hofkens +4 more
doaj +1 more source
Relevance. Cryopreserved placenta extract (CPE) increase the resistance of the mucous membrane of the gastrointestinal tract to the damaging effects of nonsteroidal anti-inflammatory drugs.
F. V. Hladkykh
doaj +1 more source
24-hour activity and sleep profiles in arthritis
Objectives: Identify 24-hour activity-sleep profiles in adults with arthritis and explore factors associated with profile membership. Methods: Cross-sectional cohort, using baseline data from two randomized trials studying activity counselling for ...
Feehan, Lynne M. +7 more
core +1 more source
Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study. [PDF]
INTRODUCTION: Neovascularization contributes to the development of sustained synovial inflammation in the early stages of Rheumatoid Arthritis. Ultrasound (US) provides an indirect method of assessing synovial blood flow and has been shown to correlate ...
Kelly, S +23 more
core +1 more source

