Results 21 to 30 of about 6,178,785 (249)

Education mediating the associations between early life factors and frailty: a cross-sectional study of the UK Biobank

open access: yesBMJ Open, 2023
Objectives Exposures in utero and during infancy may impact the development of diseases later in life. They may be linked with development of frailty, although the mechanism is unclear.
Terence W O'Neill   +5 more
doaj   +1 more source

Visualization and phenotyping of proinflammatory antigen-specific T cells during collagen-induced arthritis in a mouse with a fixed collagen type II-specific transgenic T-cell receptor beta-chain [PDF]

open access: yes, 2010
Introduction: The Vbeta12-transgenic mouse was previously generated to investigate the role of antigen-specific T cells in collagen-induced arthritis (CIA), an animal model for rheumatoid arthritis. This mouse expresses a transgenic collagen type II (CII)
Burkhardt, H   +23 more
core   +1 more source

Results of treatment methods in the long term of experimental septic arthritis

open access: yesActa Orthopaedica et Traumatologica Turcica, 2021
The effects of synovectomy on joint cartilage destruction were investigated by late term experimental septic arthritis in 30 New Zeland rabbits. Antibiotic treatment was begun on the sixth day after staphylococcus aureus inoculation in to the knee joint ...
Murat Gurun   +3 more
doaj  

The selective inhibition of the Syk tyrosine kinase ameliorates experimental autoimmune arthritis

open access: yesFrontiers in Immunology, 2023
Autoimmune arthritis – such as rheumatoid arthritis – affect a significant proportion of the population, which can cause everyday joint pain, decreased mobility and reduced quality of life.
Eszter Káposztás   +11 more
doaj   +1 more source

The role of eicosanoids in experimental Lyme arthritis

open access: yesFrontiers in Cellular and Infection Microbiology, 2014
Experimental Lyme arthritis is an inflammatory arthritis caused by infection of mice with the spirochete, Borrelia burgdorferi. It recapitulates many of the disease parameters seen in human patients with Lyme arthritis, and thus serves as a model system ...
Charles Robert Brown   +1 more
doaj   +1 more source

Exacerbation of symptomatic arthritis by cigarette smoke in experimental arthritis.

open access: yesPLoS ONE, 2020
IntroductionEpidemiologically, cigarette smoking is a well-known risk factor for the pathogenesis of rheumatoid arthritis (RA). However, there has been few plausible explanations why cigarette smoking aggravated RA.
Jaewoo Kang   +6 more
doaj   +1 more source

Liposomal targeting of prednisolone phosphate to synovial lining macrophages during experimental arthritis inhibits M1 activation but does not favor M2 differentiation. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: To determine the effects of liposomal targeting of prednisolone phosphate (Lip-PLP) to synovial lining macrophages on M1 and M2 polarization in vitro and during experimental arthritis. MATERIAL AND METHODS: Experimental arthritis (antigen and
Wouter Hofkens   +4 more
doaj   +1 more source

EVALUATION OF THE THERAPEUTIC EFFECT OF THE COMBINED USE OF CRYOPRESERVED PLACENTA EXTRACT AND DICLOFENAC SODIUM IN EXPERIMENTAL RHEUMATOID ARTHRITIS BY HEMATOLOGICAL PARAMETERS

open access: yesМедична наука України, 2021
Relevance. Cryopreserved placenta extract (CPE) increase the resistance of the mucous membrane of the gastrointestinal tract to the damaging effects of nonsteroidal anti-inflammatory drugs.
F. V. Hladkykh
doaj   +1 more source

24-hour activity and sleep profiles in arthritis

open access: yes, 2020
Objectives: Identify 24-hour activity-sleep profiles in adults with arthritis and explore factors associated with profile membership. Methods: Cross-sectional cohort, using baseline data from two randomized trials studying activity counselling for ...
Feehan, Lynne M.   +7 more
core   +1 more source

Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study. [PDF]

open access: yes, 2015
INTRODUCTION: Neovascularization contributes to the development of sustained synovial inflammation in the early stages of Rheumatoid Arthritis. Ultrasound (US) provides an indirect method of assessing synovial blood flow and has been shown to correlate ...
Kelly, S   +23 more
core   +1 more source

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