Results 41 to 50 of about 228,975 (261)

Risk of Superficial Fungal Infections in WHIM Syndrome

open access: yesDermatology and Therapy
Introduction WHIM syndrome is a rare autosomal dominant inborn error of immunity caused by gain-of-function mutations in the chemokine receptor CXCR4. Patients with WHIM syndrome frequently suffer from an increased risk for bacterial and viral infections,
Jennifer Strong   +13 more
doaj   +1 more source

Reactivation of hepatitis B virus with immune-escape mutations after ocrelizumab treatment for multiple sclerosis [PDF]

open access: yes, 2019
Ocrelizumab is an anti-CD20 monoclonal antibody for the treatment of multiple sclerosis (MS) that is closely related to rituximab. We describe a case of hepatitis B virus (HBV) reactivation in an MS patient with resolved HBV infection receiving ...
Altieri, Marta   +11 more
core   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar   +3 more
wiley   +1 more source

Intracranial fusarium fungal abscess in an immunocompetent patient: case report and review of the literature. [PDF]

open access: yes, 2014
Introduction Fusarium spp is an omnipresent fungal species that may lead to fatal infections in immunocompromised populations. Spontaneous intracranial infection by Fusarium spp in immunocompetent individuals is exceedingly rare.
Cadden, Joseph   +6 more
core   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti   +19 more
wiley   +1 more source

Incidence and Prevalence of Septic Arthritis in Thailand: A Database from the Ministry of Public Health

open access: yesOpen Access Rheumatology: Research and Reviews, 2023
Thanit Foocharoen,1 Tippawan Onchan,2 Patnarin Pongkulkiat,2 Ajanee Mahakkanukrauh,2 Siraphop Suwannaroj,2 Chingching Foocharoen2 1Department of Orthopedics, Khon Kaen Hospital, Khon Kaen, 40000, Thailand; 2Department of Medicine, Faculty of Medicine ...
Foocharoen T   +5 more
doaj  

The Infectious Basis of ACPA-Positive Rheumatoid Arthritis

open access: yesFrontiers in Microbiology, 2017
Rheumatoid arthritis (RA) is associated with HLA-DRB1 shared epitope (HLA-DRB1SE) and anti-citrullinated protein autoantibodies (ACPAs). ACPAs precedes the onset of clinical and subclinical RA.
Lazaros I. Sakkas   +3 more
doaj   +1 more source

Outcomes of Shoulder Arthroplasty Performed for Postinfectious Arthritis. [PDF]

open access: yes, 2018
Background: The purpose of this study was to evaluate the functional outcomes, infection rate, and complications associated with shoulder arthroplasty for sequelae of prior septic arthritis.
Lazarus, Mark D.   +6 more
core   +1 more source

Antibiotics with Interleukin-15 inhibition reduces joint inflammation and bone erosions but not cartilage destruction in Staphylococcus aureus-induced arthritis [PDF]

open access: yes, 2018
Background: Staphylococcus aureus-induced arthritis causes rapid joint destruction, often leading to disabling joint damage despite antibiotics. We have previously shown that IL-15 inhibition without antibiotics is beneficial in S.
Bergmann, Berglind   +7 more
core   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

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