Results 11 to 20 of about 44,348 (178)

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis. [PDF]

Arthritis Care Res (Hoboken)
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Weiss PF, Smith JA, Colbert RA, Treemarcki E, Weisman MH, Maksymowych WP, Brunner HI, Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council.   +9 more
europepmc   +2 more sources

Different corticosteroid induction regimens in children and young people with juvenile idiopathic arthritis: the SIRJIA mixed-methods feasibility study

Health Technology Assessment, 2020
Background: In the UK, juvenile idiopathic arthritis is the most common inflammatory disorder in childhood, affecting 10 : 100,000 children and young people aged
Ashley P Jones, Dannii Clayton, Gloria Nkhoma, Frances C Sherratt, Matthew Peak, Simon R Stones, Louise Roper, Bridget Young, Flora McErlane, Tracy Moitt, Athimalaipet V Ramanan, Helen E Foster, Paula R Williamson, Samundeeswari Deepak, Michael W Beresford, Eileen M Baildam   +15 more
doaj   +1 more source

Guilt by association - what is the true risk of malignancy in children treated with etanercept for JIA?

Pediatric Rheumatology Online Journal, 2010
Recently, the Food and Drug Administration placed a "black box" label on etanercept, and other tumor necrosis factor inhibitors used to treat childhood arthritis, warning of the risk of malignancies.
Cron Randy Q, Beukelman Timothy
doaj   +1 more source

Renal involvement in pediatric rheumatologic diseases [PDF]

Childhood Kidney Diseases, 2022
Pediatric rheumatologic diseases are rare systemic diseases that can involve various organs, including the kidneys. Each rheumatologic disease can exhibit characteristic renal involvement, which requires proper treatment and diagnosis. In this review, we
Seong Heon Kim
doaj   +1 more source

Juvenile Idiopathic Arthritis

Balkan Medical Journal, 2017
Juvenile idiopathic arthritis is the most common chronic rheumatic disease of unknown aetiology in childhood and predominantly presents with peripheral arthritis.
Kenan Barut, Amra Adrovic, Sezgin Şahin, Özgür Kasapçopur   +3 more
doaj   +1 more source

Relationships among gut microbiota, plasma metabolites, and juvenile idiopathic arthritis: a mediation Mendelian randomization study

Frontiers in Microbiology
ObjectiveThe objective of this study is to investigate the causal relationship between gut microbiota and juvenile idiopathic arthritis, and to identify and quantify the potential role of plasma metabolites as mediators.MethodsUsing summary-level data ...
Bingjun Gao, Zhe Wang, Kunyao Wang, Yinghan Lei, Yan Zhuang, Zhonghua Zhou, Junfei Chen   +6 more
doaj   +1 more source

PAUCIARTICULAR JUVENILE ARTHRITIS WITH ANF-ASSOCIATED UVEITIS: CLINICAL OBSERVATION OF A FAMILY CASE (MOTHER AND DAUGHTER) WITH ANKYLOSING SPONDYLITIS IN OUTCOME IN THE MOTHER

Педиатрическая фармакология, 2014
Pauciarticular juvenile arthritis associated with antinuclear factor and uveitis with onset at an early age has a special place in the structure of juvenile arthrites. This variant of arthritis is characterized by unpredictability of nosological outcomes
I. P. Nikishina, S. V. Arsenyeva, D. L. Alexeyev, A. V. Smirnov   +3 more
doaj   +1 more source

Cytokine status and hemostasis disorders in children with juvenile idiopathic arthritis

Acta Biomedica Scientifica
Juvenile idiopathic arthritis is a chronic inflammatory joint disease in children under 16 years of age associated with pathological immune response to various antigens. Probable factors are infectious and immunogenetic.
M. V. Gomellya, A. V. Mironova, T. S. Krupskaya, A. V. Tatarinova   +3 more
doaj   +1 more source

Risk of flare in juvenile idiopathic arthritis: Is it related to the methotrexate treatment strategy or patient characteristics?

The Turkish Journal of Gastroenterology, 2023
Objectives: The study aimed to determine the factors that increase the risk of disease flare in patients with juvenile idiopathic arthritis who stopped methotrexate (MTX) monotherapy following inactive disease (ID).
Rana İşgüder, Zehra Kızıldağ, Rüya Torun, Tuncay Aydın, Balahan Makay, Erbil Ünsal   +5 more
doaj  

Imaging of juvenile spondyloarthritis. Part I: Classifications and radiographs

Journal of Ultrasonography, 2017
Juvenile spondyloarthropathies are manifested mainly by symptoms of peripheral arthritis and enthesitis. By contrast with adults, children rarely present with sacroiliitis and spondylitis.
Iwona Sudoł-Szopińska, Piotr Gietka, Michał Znajdek, Genowefa Matuszewska, Magdalena Bogucevska, Ljubinka Damjanovska-Krstikj, Slavcho Ivanoski   +6 more
doaj   +1 more source