Disease activity and disability in children with juvenile idiopathic arthritis one year following presentation to paediatric rheumatology. Results from the Childhood Arthritis Prospective Study [PDF]
Objective. Inflammatory arthritis in childhood is variable in terms of both presentation and outcome. This analysis describes disease activity in children with juvenile idiopathic arthritis (JIA) during the first year following presentation to a ...
Hyrich, Kimme L. +25 more
core +1 more source
Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis [PDF]
Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic ...
Martin, P. +12 more
core +1 more source
Background: In the UK, juvenile idiopathic arthritis is the most common inflammatory disorder in childhood, affecting 10 : 100,000 children and young people aged
Ashley P Jones +15 more
doaj +1 more source
Novel IL10 gene family associations with systemic juvenile idiopathic arthritis [PDF]
Juvenile idiopathic arthritis (JIA) is the most common cause of chronic childhood disability and encompasses a number of disease subgroups. In this study we have focused on systemic JIA (sJIA), which accounts for approximately 11% of UK JIA cases.
Woo, P +32 more
core +1 more source
Renal involvement in pediatric rheumatologic diseases [PDF]
Pediatric rheumatologic diseases are rare systemic diseases that can involve various organs, including the kidneys. Each rheumatologic disease can exhibit characteristic renal involvement, which requires proper treatment and diagnosis. In this review, we
Seong Heon Kim
doaj +1 more source
Recently, the Food and Drug Administration placed a "black box" label on etanercept, and other tumor necrosis factor inhibitors used to treat childhood arthritis, warning of the risk of malignancies.
Cron Randy Q, Beukelman Timothy
doaj +1 more source
Leflunomide or methotrexate for juvenile rheumatoid arthritis. [PDF]
BACKGROUND: We compared the safety and efficacy of leflunomide with that of methotrexate in the treatment of polyarticular juvenile rheumatoid arthritis in a multinational, randomized, controlled trial.
Lahdenne, P. +11 more
core +1 more source
A national registry for juvenile dermatomyositis and other paediatric idiopathic inflammatory myopathies: 10 years' experience; the Juvenile Dermatomyositis National (UK and Ireland) Cohort Biomarker Study and Repository for Idiopathic Inflammatory Myopathies [PDF]
Objectives: The paediatric idiopathic inflammatory myopathies (IIMs) are a group of rare chronic inflammatory disorders of childhood, affecting muscle, skin and other organs.
Juvenile Dermatomyositis Research Group +15 more
core +1 more source
Młodzieńcze idiopatyczne zapalenie stawów (JIA) jest najczęstszą przewlekłą zapalną chorobą reumatyczną wieku dziecięcego. Jest to niejednorodna grupa chorób charakteryzująca się zapaleniem stawów, cechami pozastawowymi, w tym zapaleniem błony naczyniowej oka oraz, w niektórych przypadkach, markerami laboratoryjnymi.
Aleksandra Strońska +2 more
openaire +3 more sources
Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease. [PDF]
OBJECTIVES: To study muscle biopsy tissue from patients with juvenile dermatomyositis (JDM) in order to test the reliability of a score tool designed to quantify the severity of histological abnormalities when applied to biceps humeri in addition to ...
Pilkington, Clarissa A +22 more
core +1 more source

