Results 21 to 30 of about 44,348 (178)

Review of International Registers of Patients with Systemic Juvenile Idiopathic Arthritis

Вопросы современной педиатрии, 2017
The article describes the international experience in monitoring of patients with juvenile idiopathic arthritis. The main goal of most existing international registers of children with juvenile idiopathic arthritis is to evaluate various aspects of the ...
Ekaterina I. Alekseeva, Olga L. Lomakina, Saniya I. Valieva, Tatiana M. Bzarova   +3 more
doaj   +1 more source

Validation of Patient‐Reported Outcomes Measurement Information System (PROMIS) Pediatric Measures for Children With Chronic Nonbacterial Osteomyelitis

Arthritis Care &Research, EarlyView.
Objective To assess the validity of the Patient‐Reported Outcomes Measurement Information System (PROMIS) Pediatric measures in patients with chronic nonbacterial osteomyelitis (CNO). Methods Within the longitudinal patient registry of CNO, English‐speaking patients aged 8 years and older self‐reported PROMIS Pediatric measures of fatigue, pain ...
Mary M. Eckert, Eveline Y. Wu, Melissa Oliver, Joshua Scheck, Sivia Lapidus, Ummusen Kaya Akca, Shima Yasin, Aleksander Lenert, Sara Stern, Antonella Insalaco, Manuela Pardeo, Gabriele Simonini, Edoardo Marrani, Xing Wang, Bin Huang, Leonard K. Kovalick, Natalie Rosenwasser, Erin Balay‐Destrude, Gabriel Casselman, Adriel Liau, Ava Klein, Yurong Shao, Claire Yang, Molly Briggs, Ethan Mueller, Emily Deng, Paige Rhiannon Trunnell, Iris Hamilton, Elise Machrone, Doaa Mosad Mosa, Lori Tucker, Hermann Girschick, Ronald M. Laxer, Georgina Tiller, Jonathan Akikusa, Christian M. Hedrich, Karen Onel, Fatma Dedeoglu, Marinka Twilt, Seza Ozen, Polly J. Ferguson, Laura Schanberg, Bryce B. Reeve, Yongdong Zhao   +43 more
wiley   +1 more source

Characteristics of the Onset and Evolution of Juvenile Rheumatoid Arthritis Symptoms during the First Year of its Development

Zdorovʹe Rebenka, 2015
The article presents the data about early symptoms of juvenile rheumatoid arthritis in comparison with the reactive arthritis. Description of the articular syndrome is provided, the incidence of isolated joints affection and radiologic abnormalities in ...
I.S. Lebets, N.O. Panko, O.V. Matviienko, Ye.M. Zaitseva, N.S. Shevchenko   +4 more
doaj   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Sleep Quality Assessment in Children with Juvenile Arthritis in the Komi Republic: A Comparative Cross-Sectional Study with a Control Group

Медицина и биотехнологии
Introduction. Sleep disturbances in children with juvenile idiopathic arthritis remain an insufficiently studied issue. The Child and Adolescent Sleep Checklist (CASC) is a tool used to assess sleep in children; however, evidence regarding its use in ...
Maria P. Kazakova, Ekaterina D. Kosheleva, Arina V. Rush, Natalya N. Korableva   +3 more
doaj   +1 more source

PRECORDIAL PAIN, LEUKOCYTOSIS AND BICYTOPENIA IN A TEENAGER WITH SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS UNDER IMMUNOSUPPRESSIVE THERAPY

Revista Paulista de Pediatria, 2019
Objective: To highlight the importance of the new classification criteria for the macrophage activation syndrome (MAS) in systemic juvenile idiopathic arthritis in order to reduce morbidity and mortality outcome related to this disease.
Marina de Sousa Vieira, Flávia Regina de Andrade, Letícia Maria Kolachinski Raposo Brandão, Virgínia Tafas da Nóbrega, Vanessa Ramos Guissa, José Roberto Provenza   +5 more
doaj   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

JUVENILE CHRONIC ARTHRITIS WITH EYE LESION

Научно-практическая ревматология, 2002
A bstract. Objective, to describe a series of pts with JRA/JCA and uveitis. Material and methods. The study included 81 pts with JRA and uveitis. There were 68 girls-84%, 13 boys-16%.
S O Salugina, N N Kuzmina, A L Speransky, I A Guseva, S. M. Ivanova   +4 more
doaj   +1 more source

Thioredoxin‐2 Alleviates Osteoporosis by Restraining FOXO3a Nuclear Translocation

Advanced Science, EarlyView.
Endothelial TRX2 preserves bone homeostasis by retaining FOXO3a at mitochondria and limiting TRAIL production. Loss of TRX2 or oxidative stress releases FOXO3a for nuclear translocation, increasing endothelial TRAIL secretion and driving osteoclast formation and bone loss.
Chi Zhan, Zhaocai Zhou, Yue Ding, Rong Lian, Xinyu Li, Xintong Zhang, Jie Cao, Zhonghui Tang, Zhengmei Lin, Zhi Song, Feng He   +10 more
wiley   +1 more source

OPTIMIZATION OF HEALTHCARE FOR CHILDREN WITH RHEUMATIC DISEASES IN EPOCH OF TREATMENT WITH GENETICALLY ENGINEERED BIOLOGICAL AGENTS (BY THE EXAMPLE OF THE REPUBLIC OF BASHKORTOSTAN)

Вопросы современной педиатрии, 2013
Juvenile arthritis — is the most common chronic rheumatic disorder among children, which causes rapid development of disability, decrease of the quality of life, social and psychological dysadaptation.
G. A. Shebaev, R. M. Shakirova, V. A. Malievskii, R. Z. Akhmetshin   +3 more
doaj   +1 more source