Results 1 to 10 of about 19,665 (228)
Tocilizumab in the treatment of systemic juvenile idiopathic arthritis
Miho Murakami,1 Minako Tomiita,2,3 Norihiro Nishimoto11Laboratory of Immune Regulation, Wakayama Medical University, Wakayama, 2Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, 3Department of Allergy and Rheumatology, Chiba
Murakami M, Tomiita M, Nishimoto N
doaj +6 more sources
Systemic-onset juvenile idiopathic arthritis
Systemic-onset juvenile idiopathic arthritis (SoJIA) is a systemic inflammatory disease which has up to now been classified as a category of juvenile idiopathic arthritis. However, in this context, systemic inflammation has been associated with dysregulation of the innate immune system, suggesting that it may rather be part of the spectrum of ...
Rolando Cimaz
exaly +6 more sources
Objective: To highlight the importance of the new classification criteria for the macrophage activation syndrome (MAS) in systemic juvenile idiopathic arthritis in order to reduce morbidity and mortality outcome related to this disease.
Marina de Sousa Vieira +5 more
doaj +3 more sources
Systemic juvenile idiopathic arthritis in the pediatric practice of Donetsk region
Juvenile idiopathic arthritis with systemic onset is a special, rare and the most severe variant of juvenile idiopathic arthritis. The article analyzes the clinical features of the onset and course of juvenile idiopathic arthritis with systemic onset in ...
A. A. Koniushevska +5 more
doaj +3 more sources
Extracellular vesicles in systemic juvenile idiopathic arthritis. [PDF]
Abstract Systemic juvenile idiopathic arthritis is a chronic pediatric inflammatory disease of unknown etiology, characterized by fever, rash, hepatosplenomegaly, serositis, and arthritis. We hypothesized that intercellular communication, mediated by extracellular vesicles, contributes to systemic juvenile idiopathic arthritis ...
Maller J +8 more
europepmc +3 more sources
JAK inhibitors in systemic juvenile idiopathic arthritis
ObjectiveSystemic juvenile idiopathic arthritis (SJIA) is characterized by excessive and inappropriate production of proinflammatory cytokines. Janus kinase inhibitors (JAKi) can block the downstream pathway of many cytokines.
Tingyan He, Yu Xia, Ying Luo, Jun Yang
doaj +3 more sources
Systemic juvenile idiopathic arthritis with chronic recurrent multifocal osteomyelitis in an adolescent: A case report [PDF]
Chronic recurrent multifocal osteomyelitis is a rare auto-inflammatory disease in children, with only a few reports of its association with other inflammatory diseases, such as systemic juvenile idiopathic arthritis. A 15-year-old boy was admitted due to
Mohsen Jari, Sogol Alesaeidi
doaj +2 more sources
Approach to Nail Pitting in Pediatric and Adolescent Patients: A Dermatology Perspective
This narrative review aims to discuss the etiologies of nail pitting in pediatric and adolescent patients, while providing a framework for further evaluation of possible underlying systemic conditions and their clinical findings from a dermatologic ...
Elizabeth Botto +3 more
doaj +2 more sources
Systemic juvenile idiopathic arthritis (sJIA) is characterized by arthritis, fever, rash, lymphadenopathy, hepatosplenomegaly, and serositis. Macrophage activation syndrome is the most feared complication of sJIA with a high risk of mortality.
Nicole Davidson +5 more
doaj +1 more source
Juvenile idiopathic arthritis (JIA) is the most common systemic disease causing uveitis in childhood and adolescence.
A. Martins +7 more
doaj +1 more source

