Results 21 to 30 of about 19,665 (228)

CLINICAL CASE OF TOCILIZUMAB THERAPY IN A PATIENT WITH SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS

Педиатрическая фармакология, 2013
The article presents a case of successful application of a monoclonal antibodies drug to interleukin 6 receptors (tocilizumab) at severe systemic juvenile idiopathic arthritis with the development of secondary hemophagocytic syndrome.
E. I. Alexeeva, E. I. Alexeeva, R. V. Denisova, T. V. Sleptsova   +3 more
doaj   +2 more sources

Biological therapies for the treatment of juvenile idiopathic arthritis: Lessons from the adult and pediatric experiences

Biologics: Targets & Therapy, 2008
Matthew L Stoll, Alisa C GotteDepartment of Pediatrics, Division of Rheumatology, UT Southwestern Medical Center, Dallas, TX, USAAbstract: Biologics have advanced the therapy of adult and pediatric arthritis. They have been linked to rare serious adverse
Matthew L Stoll, Alisa C Gotte
doaj   +1 more source

Association of the IL-10 gene family locus on chromosome 1 with juvenile idiopathic arthritis (JIA) [PDF]

, 2012
The cytokine IL-10 and its family members have been implicated in autoimmune diseases and we have previously reported that genetic variants in IL-10 were associated with a rare group of diseases called juvenile idiopathic arthritis (JIA). The aim of this
Bryant, A., Ursu, S., Ursu Simona, Hinks, A, Forabosco, P, Omoyinmi, E, Ebun Omoyinmi, Hamaoui, Raja, Hinks, A., Woo, P., Ebun Omoyinmi (125984), Simona Ursu (125994), Forabosco, Paola, Wendy Thomson (68038), Lewis Cathryn M., Childhood Arthritis Response to Medication Study (CHARMS), Omoyinmi, Ebun, Lucy R. Wedderburn (125999), Thomson, W, Cathryn M Lewis, Lewis, Cathryn M; id_orcid, Forabosco Paola, Raja Hamaoui, Ursu, S, Wedderburn, L.R., Wedderburn, Lucy R., Ursu, Simona, Annette Bryant, Omoyinmi Ebun, Wedderburn, LR, ?, ?, Hamaoui Raja, Hamaoui, R., Hinks Anne, Patricia Woo, Annette Bryant (125990), Wedderburn, Lucy R, Bryant, Annette, Woo, P, Lewis, C.M., Lewis, CM, Woo, Patricia, Bryant, A, Forabosco, P., Patricia Woo (60657), Gardner-Medwin, J., Lewis, Cathryn M., Raja Hamaoui (125988), Wedderburn Lucy R., Hamaoui, R, Lucy R Wedderburn, Hinks, Anne, Cathryn M. Lewis (126002), Paola Forabosco, Anne Hinks, Omoyinmi, E., BSPAR study group, Thomson, W., Thomson Wendy, Paola Forabosco (125986), Wendy Thomson, Thomson, Wendy, Woo Patricia, Anne Hinks (23498), Bryant Annette, Simona Ursu, Childhood Arthritis Prospective Study (CAPS)   +66 more
core   +1 more source

Association of the CCR5 gene with juvenile idiopathic arthritis [PDF]

, 2010
The CC chemokine receptor 5 (CCR5) has been shown to be important in the recruitment of T-helper cells to the synovium, where they accumulate, drive the inflammatory process and the consequent synovitis and joint destruction.
Martin, P., BSPAR Study Group, Barton, A., UKRAG Consortium, Worthington, J., Gardner-Medwin, J. [CAPS and BSPAR Study Groups], Thomson, W., W Thomson, Flynn, E., A Hinks, E Flynn, J Packham, Packham, J., Hinks, A., S Eyre, J Worthington, Eyre, S.; id_orcid, Eyre, S., Barton, A.; id_orcid, P Martin, Childhood Arthritis Prospective Study (CAPS), Martin, P.; id_orcid, A Barton   +22 more
core   +1 more source

Disease activity and disability in children with juvenile idiopathic arthritis one year following presentation to paediatric rheumatology. Results from the Childhood Arthritis Prospective Study [PDF]

, 2009
Objective. Inflammatory arthritis in childhood is variable in terms of both presentation and outcome. This analysis describes disease activity in children with juvenile idiopathic arthritis (JIA) during the first year following presentation to a ...
Hyrich, Kimme L., Foster, H.E., Hyrich, K.L., Gardner-Medwin, J., Hyrich, Kimme L, Thornton, J., Lal, Sham D., Lal, S.D., Adib, Navid, Baildam, Eileen, Chieng, Alice, Davidson, J., Foster, Helen E., Foster, Helen E, Wedderburn, L.R., Gardner-Medwin, Janet, Lal, Sham D, Davidson, Joyce, Thomson, W., Wedderburn, Lucy R., Thornton, Judith, Baildam, E., Chieng, A., Adib, N., Thomson, Wendy, Wedderburn, Lucy R   +25 more
core   +1 more source

Comparison of biomarkers for systemic juvenile idiopathic arthritis [PDF]

Pediatric Research, 2015
Differentiation of systemic juvenile idiopathic arthritis (SJIA) fever from other childhood fevers is often delayed due to the lack of reliable, specific biomarkers. We hypothesized that PD-L1 expression is dysregulated in SJIA monocytes and compared it to other candidate SJIA biomarkers.This pilot study enrolled children with fever without source and ...
Susan, Shenoi, Jing-Ni, Ou, Chester, Ni, Claudia, Macaubas, Vivian H, Gersuk, Carol A, Wallace, Elizabeth D, Mellins, Anne M, Stevens   +7 more
openaire   +2 more sources

Overlapping clinical features of systemic juvenile idiopathic arthritis and SARS-CoV-2-related multisystem inflammatory syndrome in children

, 2023
Introduction Differential diagnosis of the systemic juvenile idiopathic arthritis (sJIA) is often complicated, because of the variability in clinical presentation and the absence of specific signs.
Tetiana Kovalchuk, Oksana Boyarchuk
core   +1 more source

Clinical and Laboratory Profile of Patients with Newly Diagnosed Juvenile Idiopathic Arthritis: An Observational Study from a Tertiary Care Centre, Karnataka, India [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Juvenile Idiopathic Arthritis (JIA) is the most common rheumatic condition of childhood. It represents a heterogeneous group of childhood arthritis.
Sivaranjani Sethupandi, Daasara Gururaju, Anand Prahalad Rao, Nijaguna Nanjundappa   +3 more
doaj   +1 more source

Systemic Treatment for Temporomandibular Joint Arthritis in Juvenile Idiopathic Arthritis [PDF]

The Journal of Rheumatology, 2020
Within the last decade, intensified research has highlighted the orofacial consequences of juvenile idiopathic arthritis (JIA) involving the temporomandibular joint (TMJ). It has been documented that about 40% of subjects with JIA develop involvement of the TMJ1,2. Smaller studies have reported even higher frequencies of TMJ involvement3. TMJ arthritis
PETER STOUSTRUP, MARINKA TWILT, TROELS HERLIN   +2 more
openaire   +2 more sources

EFFICACY OF ETANERCEPT IN TREATMENT OF VARIOUS TYPES OF JUVENILE IDIOPATHIC ARTHRITIS

Вопросы современной педиатрии, 2013
Aim: to assess efficacy and safety of etanercept in treatment of various types of juvenile idiopathic arthritis in children under conditions of real clinical practice.
O. Yu. Konopel'ko, E. S. Zholobova, M. N. Nikolaeva, O. S. Rozvadovskaya, V. Ya. El'yashevich, E. Yu. Afonina   +5 more
doaj   +1 more source