Results 11 to 20 of about 1,405,405 (194)

Macrophage activation syndrome in a patient with systemic onset of the juvenile idiopathic arthritis

open access: yesRheumatology, 2016
Systemic onset juvenile idiopathic arthritis (sJIA) is defined as arthritis affecting one or more joint usually in the juvenile age group (< 16 years of age) with or preceded by fever of at least 2 weeks duration that is documented to be daily ...
Deepak Jain   +4 more
doaj   +2 more sources

Tocilizumab in the treatment of systemic juvenile idiopathic arthritis

open access: yesOpen Access Rheumatology: Research and Reviews, 2012
Miho Murakami,1 Minako Tomiita,2,3 Norihiro Nishimoto11Laboratory of Immune Regulation, Wakayama Medical University, Wakayama, 2Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, 3Department of Allergy and Rheumatology, Chiba
Murakami M, Tomiita M, Nishimoto N
doaj   +1 more source

Initial manifestations and clinical course of systemic onset juvenile idiopathic arthritis: A ten-year retrospective study

open access: yesJournal of the Formosan Medical Association, 2012
The diagnosis of systemic onset juvenile idiopathic arthritis (SoJIA) on disease onset is challenging and made mainly by exclusion. This study aimed to investigate the initial clinical and laboratory features of children with SoJIA in Taiwan.
Hu-Yuan Tsai   +5 more
doaj   +2 more sources

Treatment of systemic-onset juvenile arthritis with canakinumab

open access: yesOpen Access Rheumatology: Research and Reviews, 2015
Joachim Peitz, Gerd Horneff Pediatric Rheumatology Centre, Department of General Pediatrics and Neonatology, Asklepios Clinic, Sankt Augustin, Germany Abstract: Treatment of systemic-onset juvenile idiopathic arthritis is challenging, but the ...
Peitz J, Horneff G
doaj   +1 more source

ADALIMUMAB IN TREATMENT OF SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS

open access: yesВопросы современной педиатрии, 2013
A history case of systemic juvenile idiopathic arthritis with early onset and severe clinical case, resistant to treatment with standard immunosuppressive agents is represented in the article.
R. V. Denisova   +10 more
doaj   +2 more sources

Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis [PDF]

open access: yes, 2010
Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic ...
Martin, P.   +12 more
core   +2 more sources

Novel IL10 gene family associations with systemic juvenile idiopathic arthritis [PDF]

open access: yes, 2006
Juvenile idiopathic arthritis (JIA) is the most common cause of chronic childhood disability and encompasses a number of disease subgroups. In this study we have focused on systemic JIA (sJIA), which accounts for approximately 11% of UK JIA cases.
Woo, P   +32 more
core   +1 more source

Association of the IL-10 gene family locus on chromosome 1 with juvenile idiopathic arthritis (JIA) [PDF]

open access: yes, 2012
The cytokine IL-10 and its family members have been implicated in autoimmune diseases and we have previously reported that genetic variants in IL-10 were associated with a rare group of diseases called juvenile idiopathic arthritis (JIA). The aim of this
Bryant, A.   +66 more
core   +1 more source

Association of the CCR5 gene with juvenile idiopathic arthritis [PDF]

open access: yes, 2010
The CC chemokine receptor 5 (CCR5) has been shown to be important in the recruitment of T-helper cells to the synovium, where they accumulate, drive the inflammatory process and the consequent synovitis and joint destruction.
Martin, P.   +22 more
core   +1 more source

Disease activity and disability in children with juvenile idiopathic arthritis one year following presentation to paediatric rheumatology. Results from the Childhood Arthritis Prospective Study [PDF]

open access: yes, 2009
Objective. Inflammatory arthritis in childhood is variable in terms of both presentation and outcome. This analysis describes disease activity in children with juvenile idiopathic arthritis (JIA) during the first year following presentation to a ...
Hyrich, Kimme L.   +25 more
core   +1 more source

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