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Macrophage Activation Syndrome [PDF]

Hematology/Oncology Clinics of North America, 2015
Macrophage activation syndrome (MAS) is a potentially life-threatening complication of rheumatic disorders that occurs most commonly in systemic juvenile idiopathic arthritis. In recent years, there have been several advances in the understanding of the pathophysiology of MAS. Furthermore, new classification criteria have been developed.
Alberto Martini, Angelo Ravelli, Francesca Minoia   +2 more
exaly   +7 more sources

The Immunology of Macrophage Activation Syndrome [PDF]

Frontiers in Immunology, 2019
Synonymous with secondary hemophagocytic lymphohistiocytosis, macrophage activation syndrome (MAS) is a term used by rheumatologists to describe a potentially life-threatening complication of systemic inflammatory disorders, most commonly systemic ...
Courtney B. Crayne, Sabrin Albeituni, Kim E. Nichols, Randy Q. Cron   +3 more
doaj   +3 more sources

Macrophage activation syndrome and COVID-19 [PDF]

Inflammation and Regeneration, 2020
An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating pandemic. As we have not developed curative medicine and effective vaccine, the end of this life-threatening infectious disease is still unclear.
Ryo Otsuka, Ken-ichiro Seino
doaj   +3 more sources

Macrophage activation syndrome

Indian Journal of Rheumatology, 2012
Abstract Macrophage activation syndrome (MAS) is a serious, potentially life-threatening complication of rheumatic disorders, which is seen most commonly in systemic juvenile idiopathic arthritis (sJIA). It is characterised clinically by unremitting high fever, pancytopaenia, hepatosplenomegaly, hepatic dysfunction, encephalopathy, coagulation ...
Bianca Lattanzi, Sergio Davi, Silvia Rosina, Nicoletta Solari, Stefano Lanni, Giulia Bracciolini, Alberto Martini, Angelo Ravelli   +7 more
doaj   +2 more sources

Macrophage activation syndrome: I/II

Indian Journal of Rheumatology, 2009
Abstract Macrophage activation syndrome (MAS) is a potentially fatal systemic disorder which results from uncontrolled activation and proliferation of T cells and excessive activation of macrophages. It is a distinct clinicopathologic entity that occurs in different haemophagocytic syndromes (HSs).
J Kotwal, K Shanmuganandan
doaj   +2 more sources

A Review on Macrophage Activation Syndrome

Journal of Pure and Applied Microbiology, 2019
MAS, which is currently grouped under secondary or acquired haemophagocytic lymphohistiocytosis (sHLH), is a rare and fatal disorder that results from excess activation of T-cells and macrophages.
Preeti Sharma, Shailza Shreshtha, Pradeep Kumar, Rachna Sharma, T.K. Mahapatra   +4 more
doaj   +3 more sources

Macrophage Activation Syndrome in Viral Sepsis

Viruses
Macrophage activation syndrome (MAS) is a life-threatening systemic hyperinflammatory syndrome triggered by various infections, particularly viral infections, autoimmune disorders, and malignancy. The condition is characterized by an increased production
Despoina Papageorgiou, Charalambos Gogos, Karolina Akinosoglou   +2 more
doaj   +3 more sources

Macrophage activation syndrome complicating early course of adult-onset Still’s disease [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2021
Introduction. Adult-onset Still’s disease is a rare inflammatory disorder of unknown etiology. It can be complicated by macrophage activation syndrome, a potentially life-threatening condition. While macrophage activation syndrome and adult-onset Still’s
Božić Ksenija, Elez Marija, Glišić Branislava   +2 more
doaj   +1 more source

Macrophage Activation Syndrome

International Journal of Surgical Pathology, 2013
Macrophage activation syndrome (MAS) is an infrequent but potentially life-threatening complication of various autoimmune diseases. It is characterized by excessive activation of macrophages induced by a dysfunction of the immune system, although the underlying abnormalities remain to be delineated.
Nidhi, Aggarwal, Rohit, Aggarwal
  +8 more sources

Macrophage Activation Syndrome in Children: Diagnosis and Management [PDF]

Indian Pediatrics, 2021
Macrophage activation syndrome is a severe yet under-recognized complication encountered in pediatric rheumatology. It manifests as secondary hemophagocytic lymphohistiocytosis leading to a hyper-inflammatory state resulting from an underlying cytokine storm. If unchecked, it may lead to multiorgan failure and mortality.
Bagri, Narendra Kumar, Gupta, Latika, Sen, Ethan S, Ramanan, A V   +3 more
openaire   +3 more sources