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Macrophage Activation Syndrome [PDF]

open access: yesHematology/Oncology Clinics of North America, 2015
Macrophage activation syndrome (MAS) is a potentially life-threatening complication of rheumatic diseases such as systemic juvenile idiopathic arthritis (sJIA) and systemic lupus erythematosus.
Angelo Ravelli   +2 more
exaly   +10 more sources

Macrophage Activation Syndrome in Viral Sepsis [PDF]

open access: yesViruses
Macrophage activation syndrome (MAS) is a life-threatening systemic hyperinflammatory syndrome triggered by various infections, particularly viral infections, autoimmune disorders, and malignancy. The condition is characterized by an increased production
Despoina Papageorgiou   +2 more
doaj   +4 more sources

The Immunology of Macrophage Activation Syndrome [PDF]

open access: yesFrontiers in Immunology, 2019
Synonymous with secondary hemophagocytic lymphohistiocytosis, macrophage activation syndrome (MAS) is a term used by rheumatologists to describe a potentially life-threatening complication of systemic inflammatory disorders, most commonly systemic ...
Courtney B. Crayne   +3 more
doaj   +3 more sources

Macrophage activation syndrome in a child with varicella: a case report [PDF]

open access: yesJournal of Medical Case Reports
Background Macrophage activation syndrome is a severe, potentially fatal condition that belongs to the group of hemophagocytic lymphohistiocytosis.
H. Mateiko   +4 more
doaj   +2 more sources

Neutralization of IFN-γ reverts clinical and laboratory features in a mouse model of macrophage activation syndrome [PDF]

open access: yesJournal of Allergy and Clinical Immunology, 2018
BACKGROUND: The pathogenesis of macrophage activation syndrome (MAS) is not clearly understood: a large body of evidence supports the involvement of mechanisms similar to those implicated in the setting of primary hemophagocytic lymphohistiocytosis ...
Giusi Prencipe   +2 more
exaly   +3 more sources

Macrophage activation syndrome and COVID-19 [PDF]

open access: yesInflammation and Regeneration, 2020
An emerging, rapidly spreading coronavirus SARS-CoV-2 is causing a devastating pandemic. As we have not developed curative medicine and effective vaccine, the end of this life-threatening infectious disease is still unclear.
Ryo Otsuka, Ken-ichiro Seino
doaj   +3 more sources

Macrophage activation syndrome

open access: yesIndian Journal of Rheumatology, 2012
Abstract Macrophage activation syndrome (MAS) is a serious, potentially life-threatening complication of rheumatic disorders, which is seen most commonly in systemic juvenile idiopathic arthritis (sJIA). It is characterised clinically by unremitting high fever, pancytopaenia, hepatosplenomegaly, hepatic dysfunction, encephalopathy, coagulation ...
Bianca Lattanzi   +7 more
doaj   +2 more sources

Macrophage activation syndrome: I/II

open access: yesIndian Journal of Rheumatology, 2009
Abstract Macrophage activation syndrome (MAS) is a potentially fatal systemic disorder which results from uncontrolled activation and proliferation of T cells and excessive activation of macrophages. It is a distinct clinicopathologic entity that occurs in different haemophagocytic syndromes (HSs).
J Kotwal, K Shanmuganandan
doaj   +2 more sources

A Review on Macrophage Activation Syndrome

open access: yesJournal of Pure and Applied Microbiology, 2019
MAS, which is currently grouped under secondary or acquired haemophagocytic lymphohistiocytosis (sHLH), is a rare and fatal disorder that results from excess activation of T-cells and macrophages.
Preeti Sharma   +4 more
doaj   +3 more sources

Macrophage activation syndrome in systemic juvenile idiopathic arthritis

open access: yesImmunological Medicine, 2021
Macrophage activation syndrome (MAS) is a severe, potentially life-threatening complication of systemic juvenile idiopathic arthritis (s-JIA). An immunological feature is the excessive activation and proliferation of T lymphocytes and macrophages ...
Masaki Shimizu
doaj   +2 more sources

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