Results 1 to 10 of about 13,338 (182)

Secondary hemophagocytic lymphohistiocytosis following blood transfusion in the absence of an identifiable trigger [PDF]

SAGE Open Medical Case Reports
Hemophagocytic lymphohistiocytosis is a life-threatening inflammatory syndrome resulting from uncontrolled immune activation. Secondary hemophagocytic lymphohistiocytosis is typically triggered by infection, malignancy, or autoimmune disease, though ...
Ashley M. Tuin, Kyle Gilkeson, Joseph Thirumalareddy   +2 more
doaj   +2 more sources

Hemophagocytic syndrome masquerading as septic shock: An approach to such dilemma

SAGE Open Medical Case Reports, 2017
Introduction: Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis is a rare condition characterized by excessive inflammation that is thought to be caused by the absence of normal downregulation of activated macrophages and lymphocytes.
Zakaria Hindi, Ashraf Abushahin
exaly   +2 more sources

Neurological symptoms of familial hemophagocytic lymphohistiocytosis type 2 [PDF]

Journal of Integrative Neuroscience, 2020
Hemophagocytic lymphohistiocytosis with central nervous system involvement is caused by inflammatory factor storms. The inflammatory factors invade the blood-brain barrier and further infiltrate brain tissue resulting in associated neurological and/or ...
Jingshi Wang, Houzhen Tuo, Lin Wu, Xinkai Wang, Zhao Wang
doaj   +1 more source

Hemophagocytic lymphohistiocytosis during pregnancy: a review of the literature in epidemiology, pathogenesis, diagnosis and treatment

Orphanet Journal of Rare Diseases, 2021
Hemophagocytic lymphohistiocytosis during pregnancy is rare; it is often misdiagnosed, resulting in a high maternal and foetal mortality rate. Herein, based on limited case reports including antepartum and postpartum cases, we reviewed the current ...
Lidong Liu, Yutong Cui, Qiongjie Zhou, Huanqiang Zhao, Xiaotian Li   +4 more
doaj   +1 more source

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Hemophagocytic Lymphohistiocytosis in the Medical ICU: A Single-Institution Cohort Study on Acute Liver Failure and Mortality

Critical Care Explorations, 2021
Objectives:. Hemophagocytic lymphohistiocytosis is a life-threatening hyperinflammatory disorder that is associated with high morbidity and mortality in the ICU. It has also been associated with acute liver failure. Design:.
Nawar Al Nasrallah, MD, Ahmad Al-Hader, MD, Niharika Samala, MBBS, Catherine R. Sears, MD, ATSF   +3 more
doaj   +1 more source

Consensus recommendations for the diagnosis and management of hemophagocytic lymphohistiocytosis associated with malignancies

Haematologica, 2015
The hyperinflammatory syndrome hemophagocytic lymphohistiocytosis can occur in the context of malignancies. Malignancy-triggered hemophagocytic lymphohistiocytosis should be regarded seperately from hemophagocytic lymphohistiocytosis during ...
Kai Lehmberg, Kim E. Nichols, Jan-Inge Henter, Michael Girschikofsky, Tatiana Greenwood, Michael Jordan, Ashish Kumar, Milen Minkov, Paul La Rosée, Sheila Weitzman   +9 more
doaj   +1 more source

Two cases of lung cancer with hemophagocytic lymphohistiocytosis caused by immune checkpoint inhibitors

Thoracic Cancer, 2021
We report the cases of two patients with secondary hemophagocytic lymphohistiocytosis caused by immune checkpoint inhibitors, who were diagnosed using the recently developed HScore.
Atsumasa Kurozumi, Hidenori Takahashi, Takayasu Watanabe, Yoshinobu Iwasaki   +3 more
doaj   +1 more source

Hemophagocytic syndrome in patients with acute myeloid leukemia undergoing intensive chemotherapy

Haematologica, 2014
Hemophagocytic lymphohistiocytosis is a condition of immune dysregulation characterized by severe organ damage induced by a hyperinflammatory response and uncontrolled T-cell and macrophage activation.
Karen Delavigne, Emilie Bérard, Sarah Bertoli, Jill Corre, Eliane Duchayne, Cécile Demur, Véronique Mansat-De Mas, Cécile Borel, Muriel Picard, Muriel Alvarez, Audrey Sarry, Françoise Huguet, Christian Récher   +12 more
doaj   +1 more source

Screening of hemophagocytic lymphohistiocytosis in children with severe sepsis in pediatric intensive care

Science Progress, 2021
Background: We sought to screen for clinical and laboratory features of hemophagocytic lymphohistiocytosis among pediatric patients with severe sepsis.
Zeinab A El-Sayed, Rasha H El-Owaidy, Mohammed A Khamis, Ahmed R Rezk   +3 more
doaj   +1 more source