Results 21 to 30 of about 13,338 (182)

Visceral leishmaniasis complicated by hemophagocytic lymphohistiocytosis: A case report from a nonendemic area

Clinical Case Reports, 2023
Key Clinical Message Visceral leishmaniasis and hemophagocytic lymphohistiocytosis share many features in common and may coincide in the same patient. Timely diagnosis and management of visceral leishmaniasis could save patients from unnecessary toxic ...
Anwar I. Joudeh, Hussein A. Elsiddig Awadelkarim, Mohammadshah Isam Gul, Mahmoud Salm Elayana, Dina Sameh Soliman, Aliaa Amer, Musaed Alsamawi   +6 more
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Babesia microti infection and hemophagocytic lymphohistiocytosis in an immunocompetent patient

International Journal of Infectious Diseases, 2017
Babesiosis is a rare and potentially severe tick-borne illness endemic to the Northeastern and upper Midwestern regions of the USA. Hemophagocytic lymphohistiocytosis is an uncommon condition resulting from over-activation of the immune system. The first
Shanette A. Go, Vania H. Phuoc, Sarah E. Eichenberg, Zelalem Temesgen, Thomas J. Beckman   +4 more
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Mycobacterium iranicum bacteremia and hemophagocytic lymphohistiocytosis: a case report

BMC Research Notes, 2017
Background Mycobacterium iranicum has recently been recognised as an opportunistic human pathogen. Although infectious conditions represent frequent triggers for hemophagocytic lymphohistiocytosis, non-tuberculous mycobacterial infections are rarely ...
Simon Grandjean Lapierre, Alexandre Toro, Michel Drancourt   +2 more
doaj   +1 more source

Successful use of emapalumab in refractory hemophagocytic lymphohistiocytosis in a child with Chédiak–Higashi syndrome: a case report

Journal of Medical Case Reports, 2023
Background Hemophagocytic lymphohistiocytosis is a life-threatening disease heralded by fever, cytopenia, hepatosplenomegaly, and multisystem organ failure.
Ali AlAhmari, Haitham Khogeer
doaj   +1 more source

Familial hemophagocytic lymphohistiocytosis [PDF]

Indian Journal of Hematology and Blood Transfusion, 2009
A 45-day-old infant presented with hepatosplenomegaly and fever since 15 days. Hemogram revealed bicytopenia and bone marrow aspirate showed hemophagocytosis. With the history of death of two siblings, the baby was diagnosed with hemophagocytic lymphohistiocytosis (HLH), likely to be of familial origin.
S, Raka, P, Nayar, R, Godbole, R, Manchanda   +3 more
openaire   +2 more sources

Prolonged hemophagocytic lymphohistiocytosis syndrome as an initial presentation of Hodgkin lymphoma: a case report

Journal of Medical Case Reports, 2008
Introduction Hemophagocytic lymphohistiocytosis is an immune-mediated syndrome that typically has a rapidly progressive course that can result in pancytopenia, coagulopathy, multi-system organ failure and death.
Chan Kathryn, Behling Eric, Strayer David S, Kocher William S, Dessain Scott K   +4 more
doaj   +1 more source

Hemophagocytic lymphohistiocytosis

Hematology/Oncology and Stem Cell Therapy, 2009
Hematol Oncol Stem Cell Ther 2(2) Second Quarter 2009 hemoncstem.edmgr.com 367 Hemophagocytic lymphohistiocytosis (HLH) is an unusual and rare syndrome characterized by fever, splenomegaly, pancytopenia, and the pathologic finding of hemophagocytosis (phagocytosis by macrophages of erythrocytes, leukocytes, platelets, and their precursors) in bone ...
Mitra, Bhaskar, Shrivastav, Ankit, Mukherjee, Krishnendu, Ghosh, Asit   +3 more
openaire   +2 more sources

The syndrome of hemophagocytic lymphohistiocytosis in primary immunodeficiencies: implications for differential diagnosis and pathogenesis

Haematologica, 2015
Hemophagocytic lymphohistiocytosis is a hyperinflammatory syndrome defined by clinical and laboratory criteria. Current criteria were created to identify patients with familial hemophagocytic lmyphohistiocytosis in immediate need of immunosuppressive ...
Sebastian FN Bode, Sandra Ammann, Waleed Al-Herz, Mihaela Bataneant, Christopher C Dvorak, Stephan Gehring, Andrew Gennery, Kimberly C Gilmour, Luis I Gonzalez-Granado, Ute Groß-Wieltsch, Marianne Ifversen, Jenny Lingman-Framme, Susanne Matthes-Martin, Rolf Mesters, Isabelle Meyts, Joris M van Montfrans, Jana Pachlopnik Schmid, Sung-Yun Pai, Pere Soler-Palacin, Uta Schuermann, Volker Schuster, Markus G. Seidel, Carsten Speckmann, Polina Stepensky, Karl-Walter Sykora, Bianca Tesi, Thomas Vraetz, Catherine Waruiru, Yenan T. Bryceson, Despina Moshous, Kai Lehmberg, Michael B Jordan, Stephan Ehl   +32 more
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Misdiagnosis of adult primary hemophagocytic lymphohistiocytosis as NK/T‐cell lymphoma: A case report

eJHaem, 2022
We reported a case of a 19‐year‐old male patient with central nervous system symptoms as the main clinical manifestations, and multiple intracranial and abdominal occupying lesions visualized by imaging examinations, who was initially misdiagnosed as NK ...
Qi Kong, Jingshi Wang, Yanlin Zhang, Junxia Hu, Mingzhu Yu, Lin Wu, Zhao Wang   +6 more
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Mutations affecting mRNA splicing are the most common molecular defect in patients with familial hemophagocytic lymphohistiocytosis type 3

Haematologica, 2008
Mutations of UNC13D have been described in patients affected by familial hemophagocytic lymphohistiocytosis (FHL3). The Munc13-4 protein contributes to the priming of the secretory granules.
Alessandra Santoro, Sonia Cannella, Antonino Trizzino, Giuseppa Bruno, Carmen De Fusco, Luigi D. Notarangelo, Daniela Pende, Gillian M. Griffiths, Maurizio Aricò   +8 more
doaj   +1 more source