Results 21 to 30 of about 20,160 (224)

Delayed Recognition of Hemophagocytic Lymphohistiocytosis in a Child With Refractory Fever: A Case From Pakistan. [PDF]

Clin Case Rep
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening, exceedingly rare hyperinflammatory syndrome that typically presents with nonspecific symptoms such as fever and cytopenia. An early diagnosis of HLH is a significant clinical challenge, especially in children with presentations mimicking common infectious diseases.
Siddiqui MT, Fatima N, Qazi K, Lal KC, Ahmed MF.   +4 more
europepmc   +2 more sources

Two cases of lung cancer with hemophagocytic lymphohistiocytosis caused by immune checkpoint inhibitors

Thoracic Cancer, 2021
We report the cases of two patients with secondary hemophagocytic lymphohistiocytosis caused by immune checkpoint inhibitors, who were diagnosed using the recently developed HScore.
Atsumasa Kurozumi, Hidenori Takahashi, Takayasu Watanabe, Yoshinobu Iwasaki   +3 more
doaj   +1 more source

Central Nervous System Involvement of Hemophagocytic Lymphohistiocytosis

, 2021
International audienceAbstract Hemophagocytic lymphohistiocytosis is rare life-threatening syndrome, hereditary or acquired, mainly affecting children. Hemophagocytic lymphohistiocytosis is an immune deficiency characterized by severe inflammation caused
Le Lez-Soquet, Servane, Querellou, Solène, Allard, Bastien, Sacaze, Elise, Delcroix, Olivier   +4 more
core   +1 more source

Hemophagocytic syndrome in patients with acute myeloid leukemia undergoing intensive chemotherapy

Haematologica, 2014
Hemophagocytic lymphohistiocytosis is a condition of immune dysregulation characterized by severe organ damage induced by a hyperinflammatory response and uncontrolled T-cell and macrophage activation.
Karen Delavigne, Emilie Bérard, Sarah Bertoli, Jill Corre, Eliane Duchayne, Cécile Demur, Véronique Mansat-De Mas, Cécile Borel, Muriel Picard, Muriel Alvarez, Audrey Sarry, Françoise Huguet, Christian Récher   +12 more
doaj   +1 more source

Screening of hemophagocytic lymphohistiocytosis in children with severe sepsis in pediatric intensive care

Science Progress, 2021
Background: We sought to screen for clinical and laboratory features of hemophagocytic lymphohistiocytosis among pediatric patients with severe sepsis.
Zeinab A El-Sayed, Rasha H El-Owaidy, Mohammed A Khamis, Ahmed R Rezk   +3 more
doaj   +1 more source

Failure of interferon gamma to induce the anti-inflammatory interleukin 18 binding protein in familial hemophagocytosis [PDF]

, 2010
Background: Familial hemophagocytosis (FHL) is a rare disease associated with defects in proteins involved in CD8+ T-cell cytotoxicity. Hyperactivation of immune cells results in a perilous, Th1-driven cytokine storm. We set out to explore the regulation
Nold Marcel F., Claudia A Nold-Petry, Jarisch Andrea, Muhl Heiko, Jarisch, Andrea, Lehrnbecher Thomas, Nold-Petry, Claudia A., Nold, Marcel Friedrich, Andrea Jarisch, Lehrnbecher, Thomas, Pfeilschifter, Josef (Prof. Dr.), Nold, Claudia, Heiko Muhl, Nold, Marcel, Dirk Schwabe, Josef M Pfeilschifter, Pfeilschifter Josef M., Thomas Lehrnbecher, Schwabe Dirk, Pfeilschifter, Josef, Nold-Petry Claudia A., Mühl, Heiko, Schwabe, Dirk, Marcel F Nold   +23 more
core   +2 more sources

Hemophagocytic Lymphohistiocytosis: an Under-recognized and Life-threatening Condition

, 2023
Diagnosis of hemophagocytic lymphohistiocytosis is a challenge in Nepal because of limited resources and the high prevalence of tropical febrile illness mimicking hemophagocytic lymphohistiocytosis.
Poudyal, Bishesh Sharma, Bishesh Sharma Poudyal, Sampurna Tuladhar, Swarup Sharma Rijal, Gentle Sunder Shrestha, Rijal, Swarup Sharma, Shrestha, Gentle Sunder, Poudel, Bishal, Bishal Poudel, Joshi, Utsav, Tuladhar, Sampurna, Utsav Joshi   +11 more
core   +1 more source

Lamotrigine-induced hemophagocytic lymphohistiocytosis with Takotsubo cardiomyopathy: a case report

Journal of Medical Case Reports, 2019
Background Hemophagocytic lymphohistiocytosis is a rare hematological syndrome characterized by excessive and uncontrolled activation of the immune system.
Jenny Y. Zhou, Jordan A. Martinez, John Paul Shen   +2 more
doaj   +1 more source

Familial hemophagocytic lymphohistiocytosis [PDF]

Indian Journal of Hematology and Blood Transfusion, 2009
A 45-day-old infant presented with hepatosplenomegaly and fever since 15 days. Hemogram revealed bicytopenia and bone marrow aspirate showed hemophagocytosis. With the history of death of two siblings, the baby was diagnosed with hemophagocytic lymphohistiocytosis (HLH), likely to be of familial origin.
S, Raka, P, Nayar, R, Godbole, R, Manchanda   +3 more
openaire   +2 more sources

A 9month-old-boy with atypical hemophagocytic lymphohistiocytosis

Mediterranean Journal of Hematology and Infectious Diseases, 2017
Hemophagocytic lymphohistiocytosis is a life-threatening hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and histiocytes. Often, Hemophagocytic lymphohistiocytosis is an acquired syndrome. We report a case of a 9 month-old-
Monia Ouederni, MONIA BEN KHALED, Samia Rekaya, Ilhem Ben Fraj, Fethi Mellouli, Mohamed Bejaoui   +5 more
doaj   +1 more source