Results 21 to 30 of about 21,033 (190)

Consensus-Based Guidelines for the Recognition, Diagnosis, and Management of Hemophagocytic Lymphohistiocytosis in Critically Ill Children and Adults [PDF]

, 2022
OBJECTIVE: Hemophagocytic lymphohistiocytosis is a hyperinflammatory syndrome that often requires critical care support and remains difficult to diagnose.
Janka, G., Lachmann, G., Paul La Rosée, Lehmberg, K., Shakoory, B., AnnaCarin Horne, Gritta Janka, Machowicz, R., La Rosée, P., Hines, M. R., Kai Lehmberg, Päivi Miettunen, Bita Shakoory, Jan-Inge Henter, Michael B. Jordan, Miettunen, P., Horne, A., Melissa R. Hines, Van Laar, J. A. M., Henter, J. I., Beutel, K., Jordan, M. B., Karin Beutel, Beutel, G., J. Allyson Hays, Tatiana von Bahr Greenwood, Jan A. M. van Laar, Hays, J. A., Gunnar Lachmann, Rafal Machowicz, Zinter, M. S., Matt S. Zinter, Gernot Beutel, Von Bahr Greenwood, T., Horne, AnnaCarin, Miettunen, Päivi, von Bahr Greenwood, Tatiana, Jordan, MB, Beutel, Gernot, Hays, J Allyson, Zinter, Matt S, Jordan, Michael B, Lehmberg, Kai, Shakoory, Bita, Beutel, K, van, Laar JAM, Beutel, G, van Laar, Jan A M, Hines, MR, Hines, Melissa R, Janka, G, Beutel, Karin, Janka, Gritta, Machowicz, Rafal, Horne, A,, Hays, JA, La Rosée, Paul, von, Bahr Greenwood T,, Lachmann, Gunnar, Lachmann, G, Henter, Jan-Inge   +60 more
core   +1 more source

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Hemophagocytic Lymphohistiocytosis in the Medical ICU: A Single-Institution Cohort Study on Acute Liver Failure and Mortality

Critical Care Explorations, 2021
Objectives:. Hemophagocytic lymphohistiocytosis is a life-threatening hyperinflammatory disorder that is associated with high morbidity and mortality in the ICU. It has also been associated with acute liver failure. Design:.
Nawar Al Nasrallah, MD, Ahmad Al-Hader, MD, Niharika Samala, MBBS, Catherine R. Sears, MD, ATSF   +3 more
doaj   +1 more source

Two cases of lung cancer with hemophagocytic lymphohistiocytosis caused by immune checkpoint inhibitors

Thoracic Cancer, 2021
We report the cases of two patients with secondary hemophagocytic lymphohistiocytosis caused by immune checkpoint inhibitors, who were diagnosed using the recently developed HScore.
Atsumasa Kurozumi, Hidenori Takahashi, Takayasu Watanabe, Yoshinobu Iwasaki   +3 more
doaj   +1 more source

Hemophagocytic syndrome in patients with acute myeloid leukemia undergoing intensive chemotherapy

Haematologica, 2014
Hemophagocytic lymphohistiocytosis is a condition of immune dysregulation characterized by severe organ damage induced by a hyperinflammatory response and uncontrolled T-cell and macrophage activation.
Karen Delavigne, Emilie Bérard, Sarah Bertoli, Jill Corre, Eliane Duchayne, Cécile Demur, Véronique Mansat-De Mas, Cécile Borel, Muriel Picard, Muriel Alvarez, Audrey Sarry, Françoise Huguet, Christian Récher   +12 more
doaj   +1 more source

Screening of hemophagocytic lymphohistiocytosis in children with severe sepsis in pediatric intensive care

Science Progress, 2021
Background: We sought to screen for clinical and laboratory features of hemophagocytic lymphohistiocytosis among pediatric patients with severe sepsis.
Zeinab A El-Sayed, Rasha H El-Owaidy, Mohammed A Khamis, Ahmed R Rezk   +3 more
doaj   +1 more source

Severe <i>Plasmodium vivax</i> Malaria Complicated by Secondary Hemophagocytic Lymphohistiocytosis, Disseminated Intravascular Coagulation, and Acute Pancreatitis: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Plasmodium vivax (P. vivax) malaria, once regarded as a comparatively benign infection, is increasingly recognized as a cause of severe, potentially life‐threatening multisystem disease. Concurrent secondary hemophagocytic lymphohistiocytosis (HLH), disseminated intravascular coagulation (DIC), and acute pancreatitis complicating P.
Nafian T, Azad MAK, Murshed KM, Aftab KA, Shahriar R, Faisal AA.   +5 more
europepmc   +2 more sources

Hemophagocytic Lymphohistiocytosis: an Under-recognized and Life-threatening Condition

, 2023
Diagnosis of hemophagocytic lymphohistiocytosis is a challenge in Nepal because of limited resources and the high prevalence of tropical febrile illness mimicking hemophagocytic lymphohistiocytosis.
Poudyal, Bishesh Sharma, Bishesh Sharma Poudyal, Sampurna Tuladhar, Swarup Sharma Rijal, Gentle Sunder Shrestha, Shrestha, Gentle Sunder, Poudel, Bishal, Bishal Poudel, Joshi, Utsav, Tuladhar, Sampurna, Utsav Joshi, rijal, swarup sharma   +11 more
core   +1 more source

Lamotrigine-induced hemophagocytic lymphohistiocytosis with Takotsubo cardiomyopathy: a case report

Journal of Medical Case Reports, 2019
Background Hemophagocytic lymphohistiocytosis is a rare hematological syndrome characterized by excessive and uncontrolled activation of the immune system.
Jenny Y. Zhou, Jordan A. Martinez, John Paul Shen   +2 more
doaj   +1 more source

A 9month-old-boy with atypical hemophagocytic lymphohistiocytosis

Mediterranean Journal of Hematology and Infectious Diseases, 2017
Hemophagocytic lymphohistiocytosis is a life-threatening hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and histiocytes. Often, Hemophagocytic lymphohistiocytosis is an acquired syndrome. We report a case of a 9 month-old-
Monia Ouederni, MONIA BEN KHALED, Samia Rekaya, Ilhem Ben Fraj, Fethi Mellouli, Mohamed Bejaoui   +5 more
doaj   +1 more source