Results 11 to 20 of about 21,033 (190)

Consensus recommendations for the diagnosis and management of hemophagocytic lymphohistiocytosis associated with malignancies [PDF]

Haematologica, 2015
The hyperinflammatory syndrome hemophagocytic lymphohistiocytosis can occur in the context of malignancies. Malignancy-triggered hemophagocytic lymphohistiocytosis should be regarded seperately from hemophagocytic lymphohistiocytosis during ...
Kai Lehmberg, Kim E. Nichols, Jan-Inge Henter, Michael Girschikofsky, Tatiana Greenwood, Michael Jordan, Ashish Kumar, Milen Minkov, Paul La Rosée, Sheila Weitzman   +9 more
doaj   +2 more sources

Hemophagocytic syndrome masquerading as septic shock: An approach to such dilemma

SAGE Open Medical Case Reports, 2017
Introduction: Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis is a rare condition characterized by excessive inflammation that is thought to be caused by the absence of normal downregulation of activated macrophages and lymphocytes.
Ashraf Abushahin, Zakaria Hindi, Abdallah A Khaled   +2 more
exaly   +2 more sources

Hemophagocytic lymphohistiocytosis: a case series of a Brazilian institution

Revista Brasileira de Hematologia e Hemoterapia, 2014
Objective:To describe the clinical and laboratory presentation of hemophagocytic lymphohistiocytosis in children treated at a referral institution.Methods:A retrospective descriptive study was carried out of seven children diagnosed with hemophagocytic ...
Daniela Guimarães Rocha Ferreira, Paulo do Val Rezende, Mitiko Murao, Marcos Borato Viana, Benigna Maria de Oliveira   +4 more
doaj   +2 more sources

Spinal cord involvement in a child with familial hemophagocytic lymphohistiocytosis

Journal of Pediatric Neurosciences, 2012
The involvement of the central nervous system (CNS) in familial hemophagocytic lymphohistiocytosis (FHL) has known to be limited to the brain, brain stem, and cerebellum.
Muge Gokce, Gunay Balta, Sule Unal, Kader Oguz, Mualla Cetin, Fatma Gumruk   +5 more
doaj   +2 more sources

Lymphoma-associated hemophagocytic lymphohistiocytosis

Hematology, Transfusion and Cell Therapy
Hemophagocytic lymphohistiocytosis is a severe, rare condition characterized by excessive immune activation, leading to significant morbidity and mortality.
Thomás de Souza Patto Marcondes, Carlos Sérgio Chiattone, Rafael Dezen Gaiolla   +2 more
doaj   +2 more sources

Severe dengue, aneurysmal sub-arachnoid hemorrhage, and hemophagocytic lymphohistiocytosis: a rare case combination [PDF]

Einstein (São Paulo)
Dengue, a vector-borne acute febrile illness caused by members of the Flavivirus genus, has dramatically increased its occurrence worldwide. Neurological complications of dengue range from 2.63 to 40%, and subarachnoid hemorrhage is a rare, but ...
Saboor Mateen, Ajay Mishra, Shivesh Singh, Firdaus Jabeen   +3 more
doaj   +3 more sources

Neurological symptoms of familial hemophagocytic lymphohistiocytosis type 2 [PDF]

Journal of Integrative Neuroscience, 2020
Hemophagocytic lymphohistiocytosis with central nervous system involvement is caused by inflammatory factor storms. The inflammatory factors invade the blood-brain barrier and further infiltrate brain tissue resulting in associated neurological and/or ...
Jingshi Wang, Houzhen Tuo, Lin Wu, Xinkai Wang, Zhao Wang
doaj   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care. [PDF]

Pediatr Investig
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Lilitwat W, Bhandari P.
europepmc   +2 more sources

Hemophagocytic lymphohistiocytosis during pregnancy: a review of the literature in epidemiology, pathogenesis, diagnosis and treatment

Orphanet Journal of Rare Diseases, 2021
Hemophagocytic lymphohistiocytosis during pregnancy is rare; it is often misdiagnosed, resulting in a high maternal and foetal mortality rate. Herein, based on limited case reports including antepartum and postpartum cases, we reviewed the current ...
Lidong Liu, Yutong Cui, Qiongjie Zhou, Huanqiang Zhao, Xiaotian Li   +4 more
doaj   +1 more source

Long-term clinical trajectory of microvillus inclusion disease associated with STXBP2-related familial hemophagocytic lymphohistiocytosis type 5: A case report. [PDF]

JPEN J Parenter Enteral Nutr
Abstract Familial hemophagocytic lymphohistiocytosis type 5 is caused by biallelic pathogenic variants in STXBP2, which encodes syntaxin‐binding protein, a key regulator of vesicle trafficking. In addition to immune dysregulation, patients with familial hemophagocytic lymphohistiocytosis type 5 may present with severe, persistent diarrhea associated ...
Tanaka H, Sekiguchi M, Kajiho Y, Ushiku T, Fujishiro J, Kato M.   +5 more
europepmc   +2 more sources