Results 31 to 40 of about 21,033 (190)

Central Nervous System Involvement of Hemophagocytic Lymphohistiocytosis

, 2021
International audienceAbstract Hemophagocytic lymphohistiocytosis is rare life-threatening syndrome, hereditary or acquired, mainly affecting children. Hemophagocytic lymphohistiocytosis is an immune deficiency characterized by severe inflammation caused
Le Lez-Soquet, Servane, Querellou, Solène, Allard, Bastien, Sacaze, Elise, Delcroix, Olivier   +4 more
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Emapalumab in children with primary hemophagocytic lymphohistiocytosis [PDF]

, 2020
Primary hemophagocytic lymphohistiocytosis is a rare syndrome characterized by immune dysregulation and hyperinflammation.
Grom, Alexei, Locatelli, Franco, Lapeyre, Genevieve, de Min, Cristina, Rao, Anupama, De Benedetti, Fabrizio, Fagioli, Franca, Ahlmann, Martina, Jordan, Michael B, Rizzari, Carmelo, Garrington, Timothy P, Sevilla, Julian, Henry, Michael, Jacqmin, Philippe, Fagioli, F., Putti, Maria-Caterina, Ballabio, Maria, Degar, Barbara, Cesaro, Simone, Allen, Carl, Dapena Diaz, Jose-Luis, Locatelli F.   +21 more
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Evaluation of children with haemophagocytic lymphohistiocytosis (HLH) at Red Cross War Memorial Children's Hospital 1991-2010 [PDF]

, 2011
Includes bibliographical references.Haemophagocytic Lymphohistiocytosis (HLH) is a rare haematological disorder in children. However, this is probably an underestimation due to the difficulty in diagnosing the disease.
Switala, Juli
core   +1 more source

Neurological presentation of hemophagocytic lymphohistiocytosis [PDF]

, 2015
Hemophagocytic lymphohistiocytosis (HLH) is an inflammatory disorder arising from defects in critical regulatory pathways responsible for termination of inflammatory response.
Żur-Wyrozumska, Kamila, Róg, Teresa, Mensah-Glanowska, Patrycja, Szczudlik, Andrzej   +3 more
core   +1 more source

A Hematopathology Case Study of Familial Hemophagocytic Lymphohistiocytosis (HLH)

, 2022
Hemophagocytic lymphohistiocytosis is a rare hematologic disorder caused by dysregulated immune activation and carries a high rate of mortality. It is categorized broadly into Primary (Familial ) and secondary types.
Dr. Lila Rani Vijayaraghavan, Dr. Siyad, Dr. Anjaly S S   +2 more
core   +1 more source

Wolman disease presenting with hemophagocytic lymphohistiocytosis syndrome and a novel LIPA gene variant: a case report and review of the literature 

Journal of Medical Case Reports, 2023
Background Wolman disease is a rare disease caused by the absence of functional liposomal acid lipase due to mutations in LIPA gene. It presents with organomegaly, malabsorption, and adrenal calcifications.
Kosar Asna Ashari, Aileen Azari-Yam, Mohammad Shahrooei, Vahid Ziaee   +3 more
doaj   +1 more source

Hemophagocytic Lymphohistiocytosis Secondary to Disseminated Histoplasmosis A Report of 3 Cases and Review of the Literature

, 2022
Hemophagocytic lymphohistiocytosis is a syndrome of immune dysregulation that can lead to an overwhelming inflammatory state. In this case series, we describe 3 cases in which disseminated Histoplasma capsulatum infection caused hemophagocytic ...
Maki, Gina, Herc, Erica, Linder, Kathleen A, Wasylyshyn, Anastasia   +3 more
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Senescence-accelerated mice (SAMP1/TA-1) treated repeatedly with lipopolysaccharide develop a condition that resembles hemophagocytic lymphohistiocytosis

Haematologica, 2019
Hemophagocytic lymphohistiocytosis is a life-threatening systemic hyperinflammatory disorder with primary and secondary forms. Primary hemophagocytic lymphohistiocytosis is associated with inherited defects in various genes that affect the immunological ...
Isao Tsuboi, Tomonori Harada, Yoko Hirabayashi, Shin Aizawa   +3 more
doaj   +1 more source

Repeated pulmonary nodules as the primary symptom of familial hemophagocytic lymphohistiocytosis in adults: a case report and review

Journal of International Medical Research, 2023
Pulmonary nodules are usually considered to be associated with malignant tumors and benign lesions, such as granuloma, pulmonary lymph nodes, fibrosis, and inflammatory lesions.
Lulu Zhang, Chuanchuan Dong, Qiannan Wu, Yupeng Li, Liting Feng, Yanqing Xing, Yangdou Dong, Le Liu, Xiaohui Li, Rujie Huo, Yanting Dong, Erjing Cheng, Xiaoyan Ge, Tian Xinrui   +13 more
doaj   +1 more source

Development and validation of a predictive model for diagnosing EBER-positive lymphoma-associated hemophagocytic lymphohistiocytosis

BMC Cancer
Purpose This study aims to identify distinguishing factors between EBER-positive lymphoma-associated hemophagocytic lymphohistiocytosis and non-neoplastic EBV-associated hemophagocytic lymphohistiocytosis.
Yuhong Yin, Wenzhi Zhang, Lizhen Zhao, Ying Li, Minchun Huang, Yu Han, Xiaoyan Wu   +6 more
doaj   +1 more source