Results 31 to 40 of about 22,112 (212)

Hemophagocytic syndrome masquerading as septic shock: An approach to such dilemma

SAGE Open Medical Case Reports, 2017
Introduction: Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis is a rare condition characterized by excessive inflammation that is thought to be caused by the absence of normal downregulation of activated macrophages and lymphocytes.
Zakaria Hindi, Abdallah A Khaled, Ashraf Abushahin   +2 more
doaj   +1 more source

Hemophagocytosis in the Acute Phase of Fatal Kawasaki Disease in a 4 Month-Old Girl

Balkan Medical Journal, 2016
Background: Kawasaki disease is a systemic vasculitis predominately affecting coronary arteries. Hemophagocytic lymphohistiocytosis can complicate the course of Kawasaki disease.
Vehbi Doğan, Erhan Karaaslan, Samet Özer, Rüveyda Gümüşer, Resul Yılmaz   +4 more
doaj   +1 more source

Mycobacterium iranicum bacteremia and hemophagocytic lymphohistiocytosis: a case report

BMC Research Notes, 2017
Background Mycobacterium iranicum has recently been recognised as an opportunistic human pathogen. Although infectious conditions represent frequent triggers for hemophagocytic lymphohistiocytosis, non-tuberculous mycobacterial infections are rarely ...
Simon Grandjean Lapierre, Alexandre Toro, Michel Drancourt   +2 more
doaj   +1 more source

Visceral leishmaniasis complicated by hemophagocytic lymphohistiocytosis: A case report from a nonendemic area

Clinical Case Reports, 2023
Key Clinical Message Visceral leishmaniasis and hemophagocytic lymphohistiocytosis share many features in common and may coincide in the same patient. Timely diagnosis and management of visceral leishmaniasis could save patients from unnecessary toxic ...
Anwar I. Joudeh, Hussein A. Elsiddig Awadelkarim, Mohammadshah Isam Gul, Mahmoud Salm Elayana, Dina Sameh Soliman, Aliaa Amer, Musaed Alsamawi   +6 more
doaj   +1 more source

Targeted high-throughput sequencing for genetic diagnostics of hemophagocytic lymphohistiocytosis [PDF]

, 2015
Background: Hemophagocytic lymphohistiocytosis (HLH) is a rapid-onset, potentially fatal hyperinflammatory syndrome. A prompt molecular diagnosis is crucial for appropriate clinical management.
Abboud, Miguel, Akar, Himmet Haluk, Belen, Burcu, Ben Bdira, Eya, Bryceson, Yenan T., Chiang, Samuel C. C., Devecioglu, Omer, Erichsen, Hans Christian, Fadoo, Zehra, Henter, Jan-Inge, Hästbacka, Johanna, Kaya, Zuhre, Lagerstedt-Robinson, Kristina, Meeths, Marie, Mottonen, Merja, Nordenskjold, Magnus, Nunes, Susana, Patiroglu, Turkan, Sabel, Magnus, Saribeyoglu, Ebru Tugrul, Tesi, Bianca, Tvedt, Tor Henrik, Unal, Ekrem, Unal, Sule, Unuvar, Aysegul, Yeoh, Allen E. J.   +25 more
core   +3 more sources

Babesia microti infection and hemophagocytic lymphohistiocytosis in an immunocompetent patient

International Journal of Infectious Diseases, 2017
Babesiosis is a rare and potentially severe tick-borne illness endemic to the Northeastern and upper Midwestern regions of the USA. Hemophagocytic lymphohistiocytosis is an uncommon condition resulting from over-activation of the immune system. The first
Shanette A. Go, Vania H. Phuoc, Sarah E. Eichenberg, Zelalem Temesgen, Thomas J. Beckman   +4 more
doaj   +1 more source

Successful use of emapalumab in refractory hemophagocytic lymphohistiocytosis in a child with Chédiak–Higashi syndrome: a case report

Journal of Medical Case Reports, 2023
Background Hemophagocytic lymphohistiocytosis is a life-threatening disease heralded by fever, cytopenia, hepatosplenomegaly, and multisystem organ failure.
Ali AlAhmari, Haitham Khogeer
doaj   +1 more source

Prolonged hemophagocytic lymphohistiocytosis syndrome as an initial presentation of Hodgkin lymphoma: a case report

Journal of Medical Case Reports, 2008
Introduction Hemophagocytic lymphohistiocytosis is an immune-mediated syndrome that typically has a rapidly progressive course that can result in pancytopenia, coagulopathy, multi-system organ failure and death.
Chan Kathryn, Behling Eric, Strayer David S, Kocher William S, Dessain Scott K   +4 more
doaj   +1 more source

Mutations affecting mRNA splicing are the most common molecular defect in patients with familial hemophagocytic lymphohistiocytosis type 3

Haematologica, 2008
Mutations of UNC13D have been described in patients affected by familial hemophagocytic lymphohistiocytosis (FHL3). The Munc13-4 protein contributes to the priming of the secretory granules.
Alessandra Santoro, Sonia Cannella, Antonino Trizzino, Giuseppa Bruno, Carmen De Fusco, Luigi D. Notarangelo, Daniela Pende, Gillian M. Griffiths, Maurizio Aricò   +8 more
doaj   +1 more source

Hemophagocytic lymphohistiocytosis

Hematology/Oncology and Stem Cell Therapy, 2009
Hematol Oncol Stem Cell Ther 2(2) Second Quarter 2009 hemoncstem.edmgr.com 367 Hemophagocytic lymphohistiocytosis (HLH) is an unusual and rare syndrome characterized by fever, splenomegaly, pancytopenia, and the pathologic finding of hemophagocytosis (phagocytosis by macrophages of erythrocytes, leukocytes, platelets, and their precursors) in bone ...
Mitra, Bhaskar, Shrivastav, Ankit, Mukherjee, Krishnendu, Ghosh, Asit   +3 more
openaire   +3 more sources