Clinical Case Reports, 2023 Key Clinical Message Visceral leishmaniasis and hemophagocytic lymphohistiocytosis share many features in common and may coincide in the same patient. Timely diagnosis and management of visceral leishmaniasis could save patients from unnecessary toxic ...
Anwar I. Joudeh +6 more
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Dynamic early biomarkers predict outcomes in pediatric Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. [PDF]
Pediatr InvestigThis study elucidates the critical pathogenic mechanisms of pediatric Epstein–Barr virus‐associated hemophagocytic lymphohistiocytosis (EBV‐HLH), where EBV infection triggers a cytokine storm leading to immune cell hyperactivation and tissue damage. Dynamic plasma biomarkers (EBV‐DNA, ferritin, and interferon‐γ) effectively predict treatment response ...
Liu F +9 more
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Hemophagocytic syndrome masquerading as septic shock: An approach to such dilemma
SAGE Open Medical Case Reports, 2017 Introduction: Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis is a rare condition characterized by excessive inflammation that is thought to be caused by the absence of normal downregulation of activated macrophages and lymphocytes.
Zakaria Hindi +2 more
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Hemophagocytosis in the Acute Phase of Fatal Kawasaki Disease in a 4 Month-Old Girl
Balkan Medical Journal, 2016 Background: Kawasaki disease is a systemic vasculitis predominately affecting coronary arteries. Hemophagocytic lymphohistiocytosis can complicate the course of Kawasaki disease.
Vehbi Doğan +4 more
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Pediatric hemophagocytic lymphohistiocytosis [PDF]
Blood, 2020 Abstract Hemophagocytic lymphohistiocytosis (HLH) is a syndrome describing patients with severe systemic hyperinflammation. Characteristic features include unremitting fever, cytopenias, hepatosplenomegaly, and elevation of typical HLH biomarkers.
Scott W, Canna, Rebecca A, Marsh
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Neurological presentation of hemophagocytic lymphohistiocytosis [PDF]
, 2015 Hemophagocytic lymphohistiocytosis (HLH) is an inflammatory disorder arising from defects in critical regulatory pathways responsible for termination of inflammatory response.
Żur-Wyrozumska, Kamila +3 more
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Evaluation of children with haemophagocytic lymphohistiocytosis (HLH) at Red Cross War Memorial Children's Hospital 1991-2010 [PDF]
, 2011 Includes bibliographical references.Haemophagocytic Lymphohistiocytosis (HLH) is a rare haematological disorder in children. However, this is probably an underestimation due to the difficulty in diagnosing the disease.
Switala, Juli
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Malaria-Associated Secondary Hematophagocytic Lymphohistocytosis-A Case Report and Comprehensive Literature Review (sHLH). [PDF]
Clin Case RepABSTRACT Malaria‐associated secondary HLH, though rare, is often overlooked. Clinicians should maintain a high‐index of suspicion in travelers returning from malaria‐endemic regions who develop severe to rapidly worsening inflammatory illness, as early recognition is critical for survival.
Yadav I +4 more
europepmc +2 more sources
A Hematopathology Case Study of Familial Hemophagocytic Lymphohistiocytosis (HLH)
, 2022 Hemophagocytic lymphohistiocytosis is a rare hematologic disorder caused by dysregulated immune activation and carries a high rate of mortality. It is categorized broadly into Primary (Familial ) and secondary types.
Dr. Lila Rani Vijayaraghavan +2 more
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Journal of Medical Case Reports, 2023 Background Hemophagocytic lymphohistiocytosis is a life-threatening disease heralded by fever, cytopenia, hepatosplenomegaly, and multisystem organ failure.
Ali AlAhmari, Haitham Khogeer
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