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Macrophage Activation Syndrome.

The Journal of the Association of Physicians of India, 2018
Macrophage Activation Syndrome (MAS) occurs as a severe life-threatening complication of several chronic rheumatic diseases. It is more frequent with systemic onset juvenile arthritis and adult onset Still's disease.1 It can be primary, infection related, malignancy associated or autoimmune3.
P Babu, Raj, B L, Harikrishnan, Roshan, Mampilly, R, Anand   +3 more
  +5 more sources

Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung [PDF]

, 2014
Phagocytes not only coordinate acute inflammation and host defense at mucosal sites, but also contribute to tissue damage. Respiratory infection causes a globally significant disease burden and frequently progresses to acute respiratory distress syndrome,
Tait, M A, Robb, C T, Haslett, C, Duffin, R, Fox, S, Rossi, A G, Dorward, D A, Lucas, C D; id_orcid, Allen, K C, Hirani, N, Marwick, J A   +10 more
core   +1 more source

Innate immunity and monocyte-macrophage activation in atherosclerosis [PDF]

, 2011
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Davies Alun H, Joseph Shalhoub, Mika A Falck-Hansen, Falck-Hansen Mika A, Davies, AH, Shalhoub Joseph, Monaco Claudia, Claudia Monaco, Falck-Hansen, MA, Monaco, Claudia, Shalhoub, J, Alun H Davies, Monaco, C   +12 more
core   +1 more source

Macrophage Activation Syndrome secondary to Systemic Juvenile Idiopathic Arthritis: A Case Report

Journal of Nepal Medical Association, 2021
Macrophage activation syndrome is a rare but a life threatening condition commonly associated with Systemic Juvenile Idiopathic Arthritis. Its clinical presentation includes fever, hepatosplenomegaly, hypertriglyceridemia, hypofibrinogenemia ...
Rishikesh Kafle, Anwesh Bhatta, Sumit Gami, Abhin Sapkota, Dipesh Sharma, Arabindra Yadav, Vijaya Kumar Chikanbanjar   +6 more
doaj   +1 more source

Tissue Microenvironments Define and Get Reinforced by Macrophage Phenotypes in Homeostasis or during Inflammation, Repair and Fibrosis [PDF]

, 2012
Current macrophage phenotype classifications are based on distinct in vitro culture conditions that do not adequately mirror complex tissue environments.
Anders, Hans-Joachim, Weidenbusch, Marc
core   +1 more source

Macrophage activation syndrome in systemic lupus erythematosus - a case report

Journal of Education, Health and Sport, 2023
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition that results from the immune system hyperactivation. The primary form of HLH appears mainly in children and is caused by a genetically determined failure of NK and T cells ...
Maciej Rogala, Karol Lorenc, Klaudia Jabłońska, Michał Kuc, Olga Bielawska, Tomasz Łoś, Kamila Giżewska, Marta Gulbicka   +7 more
doaj   +1 more source

Gastrointestinal system involvement characteristics in Covid -19 patients

Journal of the Pakistan Medical Association
Objective: To evaluate the involvement of gastrointestinal tract features in patients of coronavirus disease-2019, and to analyse the effects of these features on the development of critical illness, macrophage activation syndrome and mortalit Method:
Halil Atasoy, Vehbi Urcar
doaj   +1 more source

Síndrome de ativação macrofágica associada com artrite idiopática juvenil sistêmica Macrophage activation syndrome associated with systemic juvenile idiopathic arthritis

Jornal de Pediatria, 2004
OBJETIVO: Descrever as características da síndrome de ativação macrofágica associada a artrite idiopática juvenil. DESCRIÇÃO DOS CASOS: Foram analisados retrospectivamente os prontuários de 462 pacientes com artrite idiopática juvenil. Destes, sete (1,5%)
Clovis Artur A. Silva, Carlos Henrique M. Silva, Tereza Cristina M. V. Robazzi, Ana Paola N. Lotito, Alfredo Mendroni Junior, Cristina M. A. Jacob, Maria Helena B. Kiss   +6 more
doaj   +1 more source

Neuropathology in COVID-19 autopsies is defined by microglial activation and lesions of the white matter with emphasis in cerebellar and brain stem areas

Frontiers in Neurology, 2023
IntroductionThis study aimed to investigate microglial and macrophage activation in 17 patients who died in the context of a COVID-19 infection in 2020 and 2021.MethodsThrough immunohistochemical analysis, the lysosomal marker CD68 was used to detect ...
Julian A. Stein, Manuel Kaes, Sigrun Smola, Sigrun Smola, Walter J. Schulz-Schaeffer   +4 more
doaj   +1 more source

Macrophage activation syndrome in a patient with systemic onset of the juvenile idiopathic arthritis

, 2016
Systemic onset juvenile idiopathic arthritis (sJIA) is defined as arthritis affecting one or more joint usually in the juvenile age group (< 16 years of age) with or preceded by fever of at least 2 weeks duration that is documented to be daily ...
Promil Jain, Anshul Mittal, Deepak Jain, Hari K. Aggarwal, Avinash Rao   +4 more
core   +1 more source