Results 21 to 30 of about 2,829,847 (276)

Macrophage Activation Syndrome in Autoimmune Disease [PDF]

International Archives of Allergy and Immunology, 2010
Macrophage activation syndrome (MAS) is a phenomenon characterized by cytopenia, organ dysfunction, and coagulopathy associated with an inappropriate activation of macrophages. Current diagnostic criteria are imprecise, but the syndrome is now recognized as a form of hemophagocytic lymphohistiocytosis that is characteristically associated with ...
S. Deane, C. Selmi, S. S. Teuber, M. E. Gershwin   +3 more
openaire   +3 more sources

Expression of the Inhibitory CD200 Receptor Is Associated with Alternative Macrophage Activation [PDF]

, 2010
Classical macrophage activation is inhibited by the CD200 receptor (CD200R). Here, we show that CD200R expression was specifically induced on human in vitro polarized macrophages of the alternatively activated M2a subtype, generated by incubation with IL-
Brouwer, Michael S. M., Huitinga, I., Voehringer, David, Raes, G., van Eijk, Marco, Hoek, Robert M., Hamann, J., Huitinga, Inge, Koning, N., Brouwer, M.S., Raes, Geert, Pouwels, W., Voehringer, D., Koning, Nathalie, Van Eijk, M., Hoek, R.M., Pouwels, Walter, Hamann, Jörg   +17 more
core   +1 more source

Human circulating eosinophils secrete macrophage migration inhibitory factor (MIF). Potential role in asthma [PDF]

, 1998
Macrophage migration inhibitory factor (MIF) is a potent proinflammatory mediator that has been shown to potentiate lethal endotoxemia and to play a potentially important regulatory role in human acute respiratory distress syndrome (ARDS).
N Hirani, S C Donnelly, Bucala, R, Donnelly, Seamas C, A P Greening, A G Rossi, Rossi, Adriano G, Hirani, N, C Haslett, I Rahman, R Bucala, Metz, C N, C N Metz, Rahman, I, Haslett, Christopher, Greening, A. P.   +15 more
core   +1 more source

Macrophage Activation Led Acute Heart Failure Managed Successfully with Immunosuppression

Journal of Blood Medicine, 2021
Karan Seegobin,1 Muhamad Alhaj Moustafa,1 Umair Majeed,1 Jordan C Ray,2 Marwan Shaikh,1 Liuyan Jiang,3 Han W Tun1 1Department of Hematology and Medical Oncology, Mayo Clinic, Jacksonville, FL, 32224, USA; 2Departmentof Cardio-Oncology, Mayo Clinic ...
Seegobin K, Alhaj Moustafa M, Majeed U, Ray JC, Shaikh M, Jiang L, Tun HW   +6 more
doaj  

1alpha,25-Dihydroxyvitamin D3 is a potent suppressor of interferon gamma-mediated macrophage activation. [PDF]

, 2005
peer reviewed1alpha,25-Dihydroxyvitamin D3 (1alpha,25(OH)2D3), the activated vitamin D3 hormone, is a key regulator of calcium homeostasis and thereby indispensable for bone metabolism.
Bose, Jens, BALLING, Rudi, Frahm, Thomas, Ehrchen, Jan, Lengeling, Andreas, Helming, Laura, Geffers, Robert, Probst-Kepper, Michael, Schiebe, Stefanie, L. Helming   +9 more
core   +1 more source

Update in Hyperferritinemic Syndromes: Recognition and Management - A Scoping Review

Brown Journal of Hospital Medicine, 2022
Elevated serum ferritin is a marker of macrophage activation and is associated with increased mortality. The hyperferritinemic syndromes which include hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS), catastrophic ...
Athanasios Vassilopoulos, Winston McCormick, Alisha Lakhani   +2 more
doaj   +1 more source

Adult-Onset Still’s Disease Presenting as Macrophage-Activation Syndrome With Critical Illness in the Third Trimester of Pregnancy: A Case Report

Critical Care Explorations, 2021
BACKGROUND:. We report a case of a young woman with adult-onset Still’s disease presenting as macrophage-activation syndrome complicated by shock and respiratory failure during the third trimester of pregnancy. CASE SUMMARY:. A previously healthy 26-year-
Andrew T. Peters, MD, Michelle H. Prickett, MD   +1 more
doaj   +1 more source

The Role of Macrophages in the Pathogenesis of SARS-CoV-2-Associated Acute Respiratory Distress Syndrome

Frontiers in Immunology, 2021
Macrophages are cells that mediate both innate and adaptive immunity reactions, playing a major role in both physiological and pathological processes.
Anna Kosyreva, Anna Kosyreva, Dzhuliia Dzhalilova, Anastasia Lokhonina, Anastasia Lokhonina, Polina Vishnyakova, Polina Vishnyakova, Timur Fatkhudinov, Timur Fatkhudinov   +8 more
doaj   +1 more source

Oral Etoposide for Dengue Induced Haemophagocytic Lymphohistiocytosis Presented as Acute Liver Failure [PDF]

Journal of Clinical and Diagnostic Research, 2022
Dengue fever is not an uncommon arboviral infection in lieu of tropical geography. The gravity of the disease ranges from an Outpatient Department (OPD) visits for febrile illness to haemorrhagic complications like shock. Hereby, authors report a case of
Bharat Patodiya, Souwmya Iyengar, Padaki Nagaraja Rao, Anuradha Sekaran, Duvvu Nageshwar Reddy Reddy   +4 more
doaj   +1 more source

A cardinal role for cathepsin D in co-ordinating the host-mediated apoptosis of macrophages and killing of pneumococci [PDF]

, 2011
The bactericidal function of macrophages against pneumococci is enhanced by their apoptotic demise, which is controlled by the anti-apoptotic protein Mcl-1.
Francis, S. E., Calogero Tulone, Read, R. C., Sheila E. Francis, Mitchell, T.J., Read Robert C., Benny Chain, Marriott, Helen M, Deretic, V., Dockrell, David H, Marriott, H.M., Francis, Sheila E, Dockrell, David H., Whyte, M.K.B., Martin A. Bewley, Mitchell Timothy J., Timothy J Mitchell, Whyte, Moira K B, Kroemer, G., Chain, B., Moira K. B. Whyte, Helen M Marriott, Sheila E Francis, Tulone Calogero, Robert C Read, Bewley, M.A., Dockrell, D.H., Whyte Moira K. B., Whyte, Moira K. B., Marriott Helen M., Read, Robert C., Marriott, H. M., Chain, Benny, Tulone, C., Read, R.C., Mitchell, Timothy J., Whyte, Moira K.B., David H. Dockrell, Mitchell, Timothy J, Francis Sheila E., David H Dockrell, Kroemer, Guido, Moira K B Whyte, Marriott, Helen M., Chain Benny, Mitchell, T. J., Timothy J. Mitchell, Bewley, Martin A, Dockrell, D. H., Read, Robert C, Tulone, Calogero, Francis, S.E., Robert C. Read, Dockrell David H., Bewley, Martin A., Martin A Bewley, Helen M. Marriott, Bewley, M. A., Dockrell, David, Bewley Martin A., Whyte, M. K. B., Guido Kroemer, Francis, Sheila E., Kroemer Guido   +63 more
core   +1 more source