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Macrophage Activation Syndrome in Viral Sepsis
Macrophage activation syndrome (MAS) is a life-threatening systemic hyperinflammatory syndrome triggered by various infections, particularly viral infections, autoimmune disorders, and malignancy. The condition is characterized by an increased production
Despoina Papageorgiou +2 more
doaj +3 more sources
Macrophage activation syndrome
Abstract Macrophage activation syndrome (MAS) is a serious, potentially life-threatening complication of rheumatic disorders, which is seen most commonly in systemic juvenile idiopathic arthritis (sJIA). It is characterised clinically by unremitting high fever, pancytopaenia, hepatosplenomegaly, hepatic dysfunction, encephalopathy, coagulation ...
Bianca Lattanzi +7 more
doaj +2 more sources
Macrophage activation syndrome: A cause of unresponsive malaria
Macrophage activation syndrome (MAS) results from inappropriate proliferation and activation of cells of the macrophage-histiocytic lineage. Severe infections, autoimmune diseases and malignancies are known to trigger MAS in otherwise healthy individuals.
Manish Bhagat +5 more
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Macrophage activation syndrome complicating early course of adult-onset Still’s disease [PDF]
Introduction. Adult-onset Still’s disease is a rare inflammatory disorder of unknown etiology. It can be complicated by macrophage activation syndrome, a potentially life-threatening condition. While macrophage activation syndrome and adult-onset Still’s
Božić Ksenija +2 more
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Macrophage activation syndrome: I/II
Abstract Macrophage activation syndrome (MAS) is a potentially fatal systemic disorder which results from uncontrolled activation and proliferation of T cells and excessive activation of macrophages. It is a distinct clinicopathologic entity that occurs in different haemophagocytic syndromes (HSs).
J Kotwal, K Shanmuganandan
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Macrophage Activation Syndrome
Macrophage activation syndrome (MAS) is an infrequent but potentially life-threatening complication of various autoimmune diseases. It is characterized by excessive activation of macrophages induced by a dysfunction of the immune system, although the underlying abnormalities remain to be delineated.
Nidhi, Aggarwal, Rohit, Aggarwal
+8 more sources
mTORC1 links pathology in experimental models of Still’s disease and macrophage activation syndrome
Still’s disease is an inflammatory syndrome linked to the development of further immune dysregulation and hypercytokinaemia termed macrophage activation syndrome.
Zhengping Huang +30 more
doaj +1 more source
Macrophage activation syndrome in COVID-19
The novel coronavirus epidemic is characterized by high rates of morbidity and relatively high mortality. Laboratory test results in patients include leukopenia, an increase in liver function tests and ferritin levels reaching hundreds, and sometimes ...
K. N. Grigorieva +11 more
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Background Macrophage activation syndrome is classified as a secondary form of hemophagocytic lymphohistiocytosis. It is a hyperinflammatory complication observed to be comorbid with a variety of autoimmune diseases, including adult-onset Still’s disease
Wesam Gouda +5 more
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Adult-onset Still’s disease with secondary macrophage activation syndrome: a case report
We describe a case of adult-onset Still’s disease (AOSD) with secondary macrophage activation syndrome. AOSD is a rare disease with unknown origin. Rarely it’s complicated by secondary macrophage activation syndrome, which is a life-threatening disorder.
Giuseppe Nicoletti +7 more
doaj +1 more source

