Results 71 to 80 of about 784,373 (290)

ProNGF-p75NTR axis plays a proinflammatory role in inflamed joints. A novel pathogenic mechanism in chronic arthritis [PDF]

, 2017
To identify the role of mature nerve growth factor (mNGF), its immature form proNGF and their receptors in arthritis ...
Benedetti, Fabrizio De, Bracci-laudiero, Luisa, Caiello, Ivan, Magni-manzoni, Silvia, Manni, Luigi, Manzo, Antonio, Marafon, Denise Pires, Minnone, Gaetana, Prencipe, Giusi, Soligo, Marzia   +9 more
core   +1 more source

Deficiency of DEK proto‐oncogene alleviates allergic rhinitis by inhibiting RhoA/Ezrin‐mediated mitochondrial fission

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai, Yongde Jin, Jingmei Chai, Jianing Yang, Jiangang Wang, Mu Chen, Liangchang Li, Chongyang Wang, Guanghai Yan   +8 more
wiley   +1 more source

INFLUENCE OF IMMUNOSUPPRESSIVE AND GENETICALLY ENGINEERED THERAPY WITH TNF –alpha INHIBITOR INFLIXIMAB ON MINERAL DENSITY OF BONE TISSUE IN PATIENTS WITH JUVENILE ARTHRITIS

Вопросы современной педиатрии, 2010
The article presents results of a study of mineral density of bone tissue in patients with juvenile arthritis treated with immunosuppressive agents and blocker of tumor necrotizing factor (TNF) alpha infliximab.
A.O. Lisitsyn, E.I. Alexeeva, S.I. Valieva, T.M. Bzarova, R.V. Denisova, A.M. Chomakhidze, K.B. Isaeva   +6 more
doaj   +2 more sources

PSYCHONEUROLOGICAL ASPECTS OF JUVENILE RHEUMATOID ARTHRITIS

Вопросы современной педиатрии, 2009
This review describes basic aspects of neurological pathology in children with juvenile rheumatoid arthritis. Results of reviewed trials show that neurological and cognitive disorders, presenting in patients with juvenile rheumatoid arthritis, worsen ...
T.V. Podkletnova, L.M. Kuzenkova, E.I. Alexeeva   +2 more
doaj   +2 more sources

Impact of Interleukin‐1 Blockade on the Development of Macrophage Activation Syndrome in Still Disease: Incidence and Diagnostic Validity of the EULAR/ACR/PRINTO 2016 MAS Classification Criteria

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the applicability of the 2016 European Alliance of Associations for Rheumatology (EULAR)/American College of Rheumatology (ACR)/Paediatric Rheumatology International Trials Organisation (PRINTO) macrophage activation syndrome (MAS) classification criteria in patients with Still disease and systemic juvenile idiopathic arthritis ...
Remco G. A. Erkens, Greta Rogani, Laura Huber, Anouk Verwoerd, Dieneke Schonenberg‐Meinema, J. Merlijn van den Berg, Wineke Armbrust, G. Elizabeth Legger, Sylvia Kamphuis, Ellen J. H. Schatorjé, Esther P. A. H. Hoppenreijs, Joost F. Swart, Marc H. A. Jansen, Jorg van Loosdregt, Sebastiaan J. Vastert   +14 more
wiley   +1 more source

Cytokine status and hemostasis disorders in children with juvenile idiopathic arthritis

Acta Biomedica Scientifica
Juvenile idiopathic arthritis is a chronic inflammatory joint disease in children under 16 years of age associated with pathological immune response to various antigens. Probable factors are infectious and immunogenetic.
M. V. Gomellya, A. V. Mironova, T. S. Krupskaya, A. V. Tatarinova   +3 more
doaj   +1 more source

Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease: Characterization and Risk Factors

Arthritis & Rheumatology, 2019
Systemic juvenile idiopathic arthritis (JIA) is associated with a recently recognized, albeit poorly defined and characterized, lung disease (LD). The objective of this study was to describe the clinical characteristics, risk factors, and histopathologic
G. Schulert, S. Yasin, B. Carey, C. Chalk, T. Do, A. Schapiro, Ammar Husami, A. Watts, H. Brunner, J. Huggins, E. Mellins, E. Morgan, T. Ting, B. Trapnell, K. Wikenheiser-Brokamp, C. Towe, A. Grom   +16 more
semanticscholar   +1 more source

Vitamin D supplementation in the pediatric rheumatology clinic. [PDF]

, 2011
Vitamin D is capturing the attention of healthy and chronically ill populations for its potential skeletal and nonskeletal benefits. New information suggesting a role in immune modulation has led to a surge of interest among rheumatologists. Although the
Burnham, Jon M, von Scheven, Emily
core   +3 more sources

Linking Skin and Joint Inflammation in Psoriatic Arthritis through Shared CD8+ T Cell Clones

Arthritis &Rheumatology, EarlyView.
Objective Psoriatic arthritis (PsA) is an HLA class I–associated inflammatory arthritis that develops in up to 30% of people with psoriasis. We tested the hypothesis that skin and joint inflammation in PsA is linked in terms of CD8+ T cell phenotype and clonality.
Lucy E. Durham, Frances Humby, Nora Ng, Roman Laddach, Elizabeth H. Gray, Sarah E. Ryan, Kathryn J. A. Steel, Rosie Ross, Giovanni A. M. Povoleri, Rosamond Nuamah, Kathy Fung, Athul Menon Kallayil, Pawan Dhami, Bruce W. Kirkham, Leonie S. Taams   +14 more
wiley   +1 more source

Imaging of juvenile spondyloarthritis. Part I: Classifications and radiographs

Journal of Ultrasonography, 2017
Juvenile spondyloarthropathies are manifested mainly by symptoms of peripheral arthritis and enthesitis. By contrast with adults, children rarely present with sacroiliitis and spondylitis.
Iwona Sudoł-Szopińska, Piotr Gietka, Michał Znajdek, Genowefa Matuszewska, Magdalena Bogucevska, Ljubinka Damjanovska-Krstikj, Slavcho Ivanoski   +6 more
doaj   +1 more source