Results 71 to 80 of about 97,243 (208)
THE ROLE OF APOPTOSIS VIOLATIONS IN THE JUVENILE IDIOPATHIC ARTHRITIS FORMATION
Педиатрическая фармакология, 2012 We investigated the polymorphism of the gene p53 exon 4 Arg72Pro and intron 3 ins/del 16 b. p. in children with juvenile idiopathic arthritis in order to identify the influence of gene polymorphisms on the course and outcome of the disease.
A. N. Kozhevnikov +4 more
doaj +1 more source
Meeting the challenge for foot health in rheumatic diseases [PDF]
, 2004 Background: National guidelines recommend that patients with rheumatic diseases should have access to podiatry services and evidence is emerging that podiatry interventions are effective in the management of foot problems in this patient group.
Bowden, AP, Williams, AE
core +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Hypoparathyroidism, sensorineural deafness, and renal dysplasia (HDR) syndrome is caused by pathogenic variants in the GATA3 gene located on chromosome 10p14. Here we present a 10‐year‐old girl with HDR syndrome who also has oligoarticular juvenile idiopathic arthritis (JIA).
Lauren N. Meiss +8 more
wiley +1 more source
Burden of childhood-onset arthritis
Pediatric Rheumatology Online Journal, 2010 Juvenile arthritis comprises a variety of chronic inflammatory diseases causing erosive arthritis in children, often progressing to disability. These children experience functional impairment due to joint and back pain, heel pain, swelling of joints and ...
Hassett Afton L +3 more
doaj +1 more source
Efficacy of adalimumab in young children with juvenile idiopathic arthritis and chronic uveitis: A case series [PDF]
, 2014 Background: Juvenile idiopathic arthritis is a relatively common chronic disease of childhood, and is associated with persistent morbidity and extra-articular complications, one of the most common being uveitis.
Cattalini, Marco +5 more
core +2 more sources
Animal Models and Experimental Medicine, EarlyView.Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai +8 more
wiley +1 more source
Modern concepts of vitamin D role in juvenile idiopathic arthritis in children (review)
Zdorovʹe Rebenka, 2019 Arthritis is one of the most common chronic rheumatic diseases in children. Juvenile idiopathic arthritis (JIA) is the current nomenclature that is used to refer to a group of diseases that include chronic arthritis, childhood-onset arthritis of unknown ...
Y.V. Khadzhynova
doaj +1 more source
Seronegative spondyloarthropathies : a review : part I: classification and differential diagnosis [PDF]
, 1993 The seronegative spondyloarthropathies comprise a group of non-rheumatoid disorders with similar clinical, laboratory and genetic features. Recognition of new clinical features has supported the notion that they all form part of a clinical spectrum ...
Borg, Andrew A. +2 more
core
An in vivo assay for osteoclast activity using mouse calvaria
Animal Models and Experimental Medicine, EarlyView.This study describes a novel method for measuring osteoclast‐mediated bone resorption in vivo using a mouse model. Localized injection of RANKL in a basement membrane matrix above the cranium induced osteoclast‐mediated bone resorption. Utilizing micro‐computed tomography and a semiautomated three‐dimensional analysis program, osteoclast resorption pit
Christopher Grieg +2 more
wiley +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source