Results 61 to 70 of about 97,830 (260)

Disease Remission: A Scoping Review With Thematic Analysis of the Scientific Literature With Implications for Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Remission, a term used to describe a goal of treatment for some chronic diseases, has recently been proposed for chronic rhinosinusitis (CRS). However, it is unclear what remission means for CRS and why it should serve as a goal in the present‐day treatment of CRS.
Nikhil Parail, Lynn Warner, Stacey T. Gray, Claire Hopkins, Peter H. Hwang, Sarah K. Wise, Katie M. Phillips, Ahmad R. Sedaghat   +7 more
wiley   +1 more source

Current Validated Clinical and Patient Reported Disease Outcome Measures in Juvenile Idiopathic Arthritis

Open Access Rheumatology: Research and Reviews, 2023
Erin Balay-Dustrude,1,2 Susan Shenoi1,2 1Department of Pediatrics, Division of Rheumatology, University of Washington, Seattle, WA, USA; 2Department of Pediatric Rheumatology, Seattle Children’s Hospital and Research Center, Seattle, WA ...
Balay-Dustrude E, Shenoi S
doaj  

Systemic juvenile idiopathic arthritis in the pediatric practice of Donetsk region

Regulatory Mechanisms in Biosystems, 2023
Juvenile idiopathic arthritis with systemic onset is a special, rare and the most severe variant of juvenile idiopathic arthritis. The article analyzes the clinical features of the onset and course of juvenile idiopathic arthritis with systemic onset in ...
A. A. Koniushevska, N. V. Vaiser, M. V. Kuzevanova, V. V. Gerasymenko, O. V. Tymoshyna, T. R. Polesova   +5 more
doaj   +1 more source

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Juvenile arthritis caused by a novel FAMIN (LACC1) mutation in two children with systemic and extended oligoarticular course [PDF]

, 2016
Background The pathophysiological origin of juvenile idiopathic arthritis (JIA) is largely unknown. However, individuals with presumably pathogenic mutations in FAMIN have been reported, associating this gene with a rare subtype of this disorder.
Hundsdoerfer, Patrick, Kallinich, Tilmann, Krawitz, Peter, Luksch, Hella, Minden, Kirsten, Roesen-Wolff, Angela, Thorwarth, Anne, von Stuckrad, Sae-Lim   +7 more
core   +1 more source

EFFICACY OF ETANERCEPT IN TREATMENT OF VARIOUS TYPES OF JUVENILE IDIOPATHIC ARTHRITIS

Вопросы современной педиатрии, 2013
Aim: to assess efficacy and safety of etanercept in treatment of various types of juvenile idiopathic arthritis in children under conditions of real clinical practice.
O. Yu. Konopel'ko, E. S. Zholobova, M. N. Nikolaeva, O. S. Rozvadovskaya, V. Ya. El'yashevich, E. Yu. Afonina   +5 more
doaj   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

Impaired neutrophil directional chemotactic accuracy in chronic periodontitis patients [PDF]

, 2015
Aim: To investigate the chemotactic accuracy of peripheral blood neutrophils from patients with chronic periodontitis compared with matched healthy controls, before and after non-surgical periodontal therapy.
Agarwal, Andrew, Bagorda, Berridge, Biemond, Bostan, Brock, Cedergren, Champagne, Chapple, Chapple, Chapple, Choi, Clark, Cooper, Cotter, Daniel, Dias, Dias, Dias, Dickinson, Dietrich, Dyke, Dyke, Dyke, Dyke, Dyke, Fu, Fujita, Gamonal, Graves, Grossi, Haastert, Harvath, Henry, Herlihy, Herlihy, Kantarci, Kaul, Kolaczkowska, Kuiper, Kumar, Kurihara, Lakshman, Lambeth, Lavine, Matthews, Matthews, Miesel, Mizuno, Muinonen-Martin, Nibali, Niethammer, Nishizuka, Offenbacher, Pablo, Page, Partida-Sanchez, Phillips, Rahman, Sackmann, Samanta, Sapey, Toker, Tsai, Tyagi, Van Dyke, Wells, Worthen, Wright, Yagi, Yoshikawa, Zigmond   +72 more
core   +2 more sources

Treatment of systemic-onset juvenile arthritis with canakinumab

Open Access Rheumatology: Research and Reviews, 2015
Joachim Peitz, Gerd Horneff Pediatric Rheumatology Centre, Department of General Pediatrics and Neonatology, Asklepios Clinic, Sankt Augustin, Germany Abstract: Treatment of systemic-onset juvenile idiopathic arthritis is challenging, but the ...
Peitz J, Horneff G
doaj  

Single‐Cell RNA Sequencing Informs Precision Targeting of Monogenic Lupus Associated With IKZF1 Haploinsufficiency

Arthritis &Rheumatology, EarlyView.
Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng, Yejun Tan, Zhaoling Wang, Yanjie Qian, Qian Ma, Danping Shen, Meiping Lu   +6 more
wiley   +1 more source