Results 121 to 130 of about 50,209 (254)

The paradox of cancer genes in non-malignant conditions: implications for precision medicine. [PDF]

open access: yes, 2020
Next-generation sequencing has enabled patient selection for targeted drugs, some of which have shown remarkable efficacy in cancers that have the cognate molecular signatures.
Adashek, Jacob J   +3 more
core  

A Teenage Guitarist's Swollen Fingers

open access: yes
JEADV Clinical Practice, EarlyView.
Maho Matsuo, Hiroaki Iwata
wiley   +1 more source

Autoimmunity and Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga   +2 more
wiley   +1 more source

Localized Periodontitis in Young Individuals: Aggregatibacter JP2 Clone, Immunological Dysfunctions and Other Stories

open access: yesJournal of Periodontal Research, EarlyView.
This review describes the features of grade C molar‐incisor pattern periodontitis and discusses the role of A. actinomycetemcomitans in its pathogenesis and why molars and incisors are preferably affected. Possible future studies on this aggressive disease in primary and permanent dentition and emerging omics techniques for diagnosis and management are
Luigi Nibali   +3 more
wiley   +1 more source

Biologic treatments in rheumatoid arthritis and juvenile idiopathic arthritis [PDF]

open access: yes, 2006
A number of biological approaches to the management of inflammtory arthropathies have been explored. These include the development of IL-1 receptor antagonists and TNF antagonists. Four biological agents are currently marketed in Europe.
Borg, Andrew A.
core  

Anti‐Proliferative Effects of Resveratrol on Gingival Fibroblasts Derived From Amlodipine‐Induced Gingival Overgrowth

open access: yesJournal of Periodontal Research, EarlyView.
Resveratrol in repeated doses has been shown to suppress excessive cell proliferation without cytotoxic effects in amlodipine‐induced gingival hyperplasia, while not having a negative effect on mediators involved in tissue homeostasis in healthy cells, and at the same time, it reduces the expression of biomarkers involved in fibrosis processes ...
Bilkan Kara   +6 more
wiley   +1 more source

RENAL AMYLOIDOSIS IN RHEUMATIC DISEASES

open access: yesTurkish Journal of Nephrology, 2019
In this study, cases with secondary amyloidosis due to rheumatic diseases were investigated retrospectively. Sixteen female, 14 male (mean age, 34±15 years) total 30 cases were included into the study. The number of cases with renal amyloidosis secondary
Yüksel KARAKOÇ   +6 more
doaj  

Efficacy and Safety of Intra‐Articular Therapies for Temporomandibular Disorders: A Systematic Review and Meta‐Analysis

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to evaluate the most effective minimally invasive intra‐articular procedure for reducing pain and improving maximum mouth opening (MMO) in individuals diagnosed with painful articular TMD, specifically TMJ osteoarthritis and/or internal derangement.
Mateus Gaya dos Santos   +5 more
wiley   +1 more source

Juvenile Rheumatoid Arthritis [PDF]

open access: yes, 1982
Juvenile rheumatoid arthritis (JRA) (JA) has been the diagnostic label applied to any child whose arthritis is of unknown origin, begins under age 16, and persists for a minimum of 6 weeks.1,2 Arthritis is defined as swelling or both pain and limitation of motion in at least one joint.
openaire   +1 more source

Myocellular adaptations to short‐term weighted wheel‐running exercise are largely conserved during C26‐tumour induction in male and female mice

open access: yesExperimental Physiology, EarlyView.
Abstract This study investigated whether performing a translatable murine model of concurrent training after tumour induction affects adaptations in juvenile male and female tumour‐bearing mice. Male and female Balb/c mice were injected bilaterally with colon‐26 adenocarcinoma (C26) cells or PBS at 8 weeks of age.
Stavroula Tsitkanou   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy