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The Impact of Caring for a Child With Juvenile Idiopathic Arthritis on Caregiver Quality of Life
ACR Open Rheumatology, Volume 8, Issue 10, October 2026.Objective
Juvenile idiopathic arthritis (JIA) impacts children and their families, often increasing caregiver burden and diminishing quality of life. This study assessed the care‐related quality of life of parent‐caregivers of children with JIA using the Care‐Related Quality of Life instrument (CarerQol), identified the most affected caregiving ...Deborah A. Marshall, Ana Claudia Fuhrmann, Rodrigo Dal Ben, Gillian R. Currie, Rae S. M. Yeung, Sebastiaan J. Vastert, Nico Wulffraat, Joost F. Swart, Susanne Benseler, on behalf of the UCAN CAN‐DU and UCAN CURE Consortia, Rae Yeung, Shirley Tse, Deborah Levy, Ronald Laxer, Brian Feldman, Jennifer Ji Young Lee, Alisa Rachlis, Susanne Benseler, Nicole Johnson, Muhammed Dhalla, Paivi Miettunen, Heinrike Schmeling, Marinka Twilt, Rebeka Stevenson, Deborah Marshall, Andrea Human, David Cabral, Jaime Guzman, Kim Morishita, Kristin Houghton, Lori Tucker, Tommy Gerschman, Herman Tam, Mercedes Chan, Ross Petty, Roman Jurencak, Nadia Luca, Ciarán Duffy, Tala El Tal, Roberta Berard, Jonathan Park, Erkan Demirkaya, Lily Lim, Adam Huber, Bianca Lang, Elizabeth Stringer, Chelsea DeCoste, Suzanne Ramsey, Dax G. Rumsey, Daniah Basodan, Lillian Lim, Hon Yan Ng, Jeanine McColl, Tara McGrath, Michelle Batthish, Tania Cellucci, Liane Heale, Claire LeBlanc, Gaëlle Chédeville, Rosie Scuccimarri, Sarah Campillo, Piya Lahiry, Paul Dancey, Nickolas Blanchette, Alan Rosenberg, Mehul Jariwala, Tristan Kerr, Kate Neufeld, Clare Hutchinson, Gordon Soon, Dieneke Schonenberg, Mariken Gruppen, Merlijn van den Berg, Giske Biesbroek, Philomine van Pelt, Marleen Verkaaik, Sylvia Kamphuis, Danielle Brinkman, Petra Hissink Muller, Ellen Schatorje, Esther Hoppenreijs, Annet van Royen‐Kerkhof, Sebastiaan Vastert, Berent Prakken, Erika Van Nieuwenhove, Joost Swart, Marc Jansen, Nico Wulffraat, Elizabeth Legger, Wineke Armbrust, Joseph Cafazzo, Maarten IJzerman, Alexander Mosoiu, Amy Xu, Arthur Cheng, Bruno Pereira, Trang Duong, Harper Cheng, Brenleigh Jebb, Gillian R. Currie, Rodrigo Dal Ben, Ravneet Sran, Elodie Boudes, Michelle Kip, Sytze de Rook, Regina de Geus +105 morewiley +1 more sourceWork Productivity Loss and Activity Impairment in Parents of Children With Juvenile Idiopathic Arthritis
ACR Open Rheumatology, Volume 8, Issue 10, October 2026.Objective
To determine the impact of juvenile idiopathic arthritis (JIA) on work productivity loss and daily activities of parents. Methods
The multicenter Canada‐Netherlands Understanding Childhood Arthritis Network (UCAN) CAN‐DU and CURE study captures consecutive clinical and patient‐reported data for patients and parents since 2019.Deborah A. Marshall, Rodrigo Dal Ben, Gillian R. Currie, Rae S. M. Yeung, Sebastiaan J. Vastert, Nico Wulffraat, Joost F. Swart, Susanne Benseler, on behalf of the UCAN CAN‐DU and UCAN CURE Consortia, Rae Yeung, Shirley Tse, Deborah Levy, Ronald Laxer, Brian Feldman, Elizaveta Limenis, Ruud Verstegen, Lynn Spiegel, Rayfel Schneider, Evelyn Rozenblyum, Jennifer Ji Young Lee, Alisa Rachlis, Susanne Benseler, Nicole Johnson, Muhammed Dhalla, Paivi Miettunen, Heinrike Schmeling, Marinka Twilt, Rebeka Stevenson, Deborah Marshall, Andrea Human, David Cabral, Jaime Guzman, Kim Morishita, Kristin Houghton, Lori Tucker, Tommy Gerschman, Herman Tam, Mercedes Chan, Ross Petty, Roman Jurencak, Nadia Luca, Ciarán Duffy, Tala El Tal, Roberta Berard, Jonathan Park, Erkan Demirkaya, Lily Lim, Adam Huber, Bianca Lang, Elizabeth Stringer, Chelsea DeCoste, Suzanne Ramsey, Dax G. Rumsey, Daniah Basodan, Lillian Lim, Hon Yan Ng, Jeanine McColl, Tara McGrath, Michelle Batthish, Tania Cellucci, Liane Heale, Claire LeBlanc, Gaëlle Chédeville, Rosie Scuccimarri, Sarah Campillo, Piya Lahiry, Paul Dancey, Nickolas Blanchette, Alan Rosenberg, Mehul Jariwala, Tristan Kerr, Kate Neufeld, Clare Hutchinson, Gordon Soon, Dieneke Schonenberg, Mariken Gruppen, Merlijn van den Berg, Giske Biesbroek, Philomine van Pelt, Marleen Verkaaik, Sylvia Kamphuis, Danielle Brinkman, Petra Hissink Muller, Ellen Schatorje, Esther Hoppenreijs, Annet van Royen‐Kerkhof, Sebastiaan Vastert, Berent Prakken, Erika Van Nieuwenhove, Joost Swart, Marc Jansen, Nico Wulffraat, Elizabeth Legger, Wineke Armbrust, Joseph Cafazzo, Maarten IJzerman, Alexander Mosoiu, Amy Xu, Arthur Cheng, Bruno Pereira, Trang Duong, Harper Cheng, Brenleigh Jebb, Gillian R. Currie, Rodrigo Dal Ben, Ravneet Sran, Elodie Boudes, Michelle Kip, Sytze de Rook, Regina de Geus +109 morewiley +1 more sourceMucosal‐Associated Invariant T Cells in Health and Disease
MedComm, Volume 7, Issue 10, October 2026.The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang +5 morewiley +1 more sourceDrug‐Induced Liver Injury During Treatment With Tocilizumab: A Case Report of an Atypical Pattern Lesion
Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.ABSTRACT
Tocilizumab is an interleukin‐6 (IL‐6) receptor antagonist indicated for various rheumatologic conditions. While hepatotoxicity is a recognized adverse effect, it predominantly manifests as hepatocellular injury. We report a rare case of drug‐induced liver injury (DILI) presenting with a cholestatic pattern and cholangitis features in a 75 ...Louis‐Edmond Barbaro, Nouha Ben Othman, Delphine Viard, Fanny Rocher, Elliot Ewig, Raja Mroue, Claire Amigues, Alexandre O. Gérard +7 morewiley +1 more sourceRheumatologic Manifestations of Patients With Type B Insulin Resistance
Arthritis Care &Research, Volume 78, Issue 9, Page 1195-1200, September 2026.Objective
The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown +4 morewiley +1 more sourcePatient Perspectives and Expectations on the Use of Artificial Intelligence to Guide Treatment Decision‐Making in Juvenile Idiopathic Arthritis: A Qualitative Study
ACR Open Rheumatology, Volume 8, Issue 9, September 2026.Objective
Artificial intelligence (AI) is rapidly transforming clinical decision‐making. However, patient perspectives on these technologies remain understudied in pediatric care. We investigated patient and parent perspectives on AI use in juvenile idiopathic arthritis (JIA) care among a highly engaged cohort.Mei‐Sing Ong, Laura E. Schanberg, Melanie Kohlheim, Jenny Leal, Ashley Luo, Marc D. Natter, Yukiko Kimura +6 morewiley +1 more source