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Juvenile rheumatoid arthritis

Postgraduate Medicine, 1977
Juvenile rheumatoid arthritis is the condition of chronic synovitis in children. This Condition was first well described in the English literature by George Frederick Still,1 an English pediatrician and pathologist, who in 1897 described 22 children with chronic arthritis who had come to his attention while he was still in training at the Hospital for ...
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Juvenile Rheumatoid Arthritis

Pediatric Clinics of North America, 1974
Still’s disease, a clinical syndrome akin to rheumatoid arthritis as seen in adults, is distinguished by its special characteristics. Since the inciting agent is not known, and there are as yet no measurable specific or nonspecific antibodies that can help with diagnosing, monitoring the course of the disease, and directing its management, the ...
J E, Boone, J, Baldwin, C, Levine
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Juvenile rheumatoid arthritis

Arthritis & Rheumatism, 1966
The early diagnosis of JRA rests on the recognition of three distinct modes of onset that are important in preventing deformity, blindness, and even death. Systemic onset is characterized by typical systemic manifestations, particularly high spiking fever and the rheumatoid rash, polyarticular onset is noted by arthritis of more than four joints, and ...
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Juvenile Rheumatoid Arthritis

New England Journal of Medicine, 1967
Early Diagnosis In our experience, early diagnosis is greatly facilitated if the 3 distinct modes of onset of the disease previously delineated are kept in mind19: In acute disease, recurrent hecti...
J J, Calabro, J M, Marchesano
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Juvenile Rheumatoid Arthritis

Hand Clinics, 1989
Juvenile rheumatoid arthritis affects approximately 60,000 to 250,000 children in the United States and is the most common connective tissue disease occurring during childhood. This article discusses the signs, symptoms, and general management of the disease, including surgical techniques.
B P, Simmons, J T, Nutting
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Juvenile rheumatoid arthritis

Current Opinion in Rheumatology, 1999
The heterogeneous nature of juvenile rheumatoid arthritis is further defined in publications from the past year. Decreased IL-10 production, an anti-inflammatory cytokine, and soluble IL-6 receptor are associated with systemic juvenile rheumatoid arthritis (JRA).
K T, Gallagher, B, Bernstein
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Juvenile rheumatoid arthritis

Postgraduate Medicine, 1972
Juvenile rheumatoid arthritis differs in many respects from the adult disease. Diagnosis may remain obscure unless full advantage is taken of all clinical and laboratory clues. The physical, emotional and psychologic development of the child poses unique problems in physical and surgical management and special problems in drug management.
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Monarticular juvenile rheumatoid arthritis

The Journal of Pediatrics, 1967
A child with recent onset of arthritis in a single joint often presents a diagnostic problem of considerable magnitude. The diagnosis of rheumatoid arthritis may be made with certainty only after specific diseases such as tuberculosis have been clinically eliminated; even then, correct therapeutic management of this form of arthritis is complex.
J T, Cassidy, G L, Brody, W, Martel
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Juvenile rheumatoid arthritis—assessment

The Indian Journal of Pediatrics, 1996
The assessment of overall health status of a child with juvenile rheumatoid arthritis (JRA) is complex and multi-dimensional. The general physical examination is complemented by a rheumatological evaluation that includes determination of articular indices of inflammation and duration of inactivity stiffness.
T B, Graham, E H, Giannini
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Juvenile rheumatoid arthritis

Current Opinion in Rheumatology, 1993
The etiology and pathogenesis of juvenile rheumatoid arthritis remains unknown; however, research using new techniques is revealing information on the roles of immunogenetics, cellular immunity, and humoral immunity in these disorders. Interest continues in infection as a potential trigger of juvenile rheumatoid arthritis, as reactivity to infectious ...
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