Results 171 to 180 of about 492,235 (272)
Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang +10 more
wiley +1 more source
Shared Genetic Architecture Between Epigenetic Aging and Musculoskeletal Diseases. [PDF]
Xu W, Zhang X, Zhao B, Li X, Zhang R.
europepmc +1 more source
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Editorial: Genetics, microbiomes, and environmental factors in autoimmunity: from bench to bedside. [PDF]
Shaharir SS, Ali A, Adeeb F.
europepmc +1 more source
Juvenile rheumatoid arthritis (Juvenile chronic arthritis)
openaire +4 more sources
ABSTRACT Living with a chronic health condition (CHC) can involve sustained exposure to uncertainty, bodily threat and disruption to identity, relationships and anticipated life trajectories. Although a substantial evidence base exists for psychological interventions in long‐term illness, theoretical accounts remain fragmented across modalities and ...
Liza Morton
wiley +1 more source
Immune dysregulation in children with Down syndrome: clinical implications and emerging therapies. [PDF]
Bloom JL, Sriram I.
europepmc +1 more source
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
Franziska Roth‐Walter +20 more
wiley +1 more source
Tocilizumab, an IL‐6 inhibitor used in severe COVID‐19, may have cardiovascular effects. This study examined short‐term electrocardiographic (ECG) changes 24 h before versus 24 h after tocilizumab injection in PCR‐positive COVID‐19 patients. Retrospective study of 33 ICU‐admitted COVID‐19 patients (36.4% male, age 37–79 years). ECG parameters including
Mahdi Zahedi +2 more
wiley +1 more source
Temporo-mandibular joint alterations in juvenile idiopathic arthritis and young-onset inflammatory arthropathies: a magnetic resonance imaging study with ultrasound comparison. [PDF]
Lercara A +9 more
europepmc +1 more source

