Results 141 to 150 of about 32,769 (202)

T Cell‐Specific Deficiency of Src Homology 2‐Containing Protein Tyrosine Phosphatase 2 Ameliorates Psoriasis and Colitis by Promoting Treg Differentiation

open access: yesMedComm, Volume 6, Issue 8, August 2025.
• SHP2 deficiency in T cells could alleviate both psoriasis‐like skin lesion and adoptive transfer colitis. • SHP2 deficiency in T cells promotes the differentiation toward Treg, thus regulating the balance of Th17/Treg. • SHP2 may become a promising common therapeutic target in the treatment of autoimmune diseases.
Shuqiong Zhang   +7 more
wiley   +1 more source

Janus kinase inhibitors and tumour necrosis factor inhibitors show a favourable safety profile and similar persistence in rheumatoid arthritis, psoriatic arthritis and spondyloarthritis: real-world data from the BIOBADASER registry. [PDF]

open access: yesAnn Rheum Dis
Hernández-Cruz B   +13 more
europepmc   +1 more source

Real-world evidence of the impact of adalimumab on work productivity and sleep measures in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. [PDF]

open access: yesTher Adv Musculoskelet Dis, 2020
Tektonidou MG   +7 more
europepmc   +1 more source

Sulphonylureas as Adjunct Therapeutic Agents in the Treatment of Autoimmune Conditions: A Narrative Review

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
NLRP3 Inflammasome activation drives inflammatory responses through the production and activation of pro‐inflammatory cytokines. Repurposing sulphonylureas and their derivatives to target NLRP3 may act as adjunct therapeutics for autoimmune conditions. ABSTRACT A rapid and cost‐effective arm of the drug discovery and development process is finding new ...
Jasen Elford   +4 more
wiley   +1 more source

Perceived Stigma and Mental Health Disorders Among Adults With Alopecia Areata Living in Japan

open access: yesThe Journal of Dermatology, Volume 52, Issue 8, Page 1255-1262, August 2025.
ABSTRACT Alopecia areata (AA) is a common disorder that causes hair loss and can significantly impact quality of life, which may be partially due to AA‐related stigma. Examining the impact of AA on psychosocial health is important for understanding the burden experienced by patients with AA.
Norimitsu Saito   +8 more
wiley   +1 more source

Malignancy in the Upadacitinib Clinical Trials for Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, and Non-radiographic Axial Spondyloarthritis. [PDF]

open access: yesRheumatol Ther
Rubbert-Roth A   +9 more
europepmc   +1 more source

Identifying Common Patient‐Oriented Priorities for Child and Adolescent Health Research and Care: A Systematic Review of Priority Setting Partnerships

open access: yesHealth Expectations, Volume 28, Issue 4, August 2025.
ABSTRACT Context James Lind Alliance (JLA) Priority Setting Partnerships (PSPs) bring together patients, clinicians and carers (e.g., parents, guardians or family members) to identify the most important questions in specific areas of health research.
Jenna S. Jessa   +6 more
wiley   +1 more source

Frontal Sinus Patency After Sinus Surgery Using Triamcinolone‐Impregnated Plant‐Based Sinus Spacers

open access: yes
The Laryngoscope, Volume 135, Issue 8, Page 2691-2695, August 2025.
Emily Ajit‐Roger   +3 more
wiley   +1 more source

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