Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira +9 more
wiley +1 more source
Long term efficacy and safety of etanercept in the treatment of psoriasis and psoriatic arthritis
Dario Kivelevitch, Bobbak Mansouri, Alan Menter Department of Dermatology, Baylor University Medical Center, Dallas, TX, USA Abstract: Psoriasis is a chronic, immune-mediated inflammatory disease affecting both the skin and joints.
Kivelevitch D, Mansouri B, Menter A
doaj
Long-term golimumab persistence: Five-year treatment retention data pooled from pivotal Phase III clinical trials in patients with rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. [PDF]
Weinstein CLJ +4 more
europepmc +1 more source
Abstract Background The objective of this systematic review is to evaluate whether periodontitis is associated with impaired oral health–related quality of life (OHRQoL) in adults with systemic conditions. Methods Five databases were searched to identify observational studies that tested the association between periodontitis (diagnosed by clinical ...
Rafael Vargas Bortolaso +5 more
wiley +1 more source
Vasculitis associated with psoriatic arthritis: a case report
Background Psoriatic arthritis is a chronic inflammatory condition associated with psoriasis, which affects joints. The coexistence of vasculitis, an inflammation of blood vessels, with psoriatic arthritis is rare, highlighting a complex interplay ...
Mehdi Jafarpour +3 more
doaj +1 more source
Safety profile of upadacitinib over 15 000 patient-years across rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and atopic dermatitis. [PDF]
Burmester GR +13 more
europepmc +1 more source
Successful treatment of eosinophilic esophagitis with upadacitinib prescribed for atopic dermatitis
Abstract We describe a pediatric patient treated with upadacitinib for atopic dermatitis (AD) who subsequently achieved sustained clinical and histologic remission of eosinophilic esophagitis (EoE). Upadacitinib is an oral small molecule selective Janus kinase 1 inhibitor that inhibits janus kinase‐signal transduction and activation of transcription ...
Nathalie Nguyen, Maureen Bauer
wiley +1 more source
Connecting the use of innovative treatments and glucocorticoids with the multidisciplinary evaluation through rule-based natural-language processing: a real-world study on patients with rheumatoid arthritis, psoriatic arthritis, and psoriasis. [PDF]
Motta F +9 more
europepmc +1 more source

