Results 71 to 80 of about 32,769 (202)

Exploring the Cutaneous Associations of Crohn's Disease: A Retrospective Study of 108 Patients

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background The integumentary system provides a window into the overall health of individuals and may display cutaneous manifestations of systemic disease. Crohn's Disease (CD) is a relapsing inflammatory bowel disease that exhibits a significant symptomatic burden on a global scale.
Max E. Oscherwitz   +4 more
wiley   +1 more source

Case Report of a Patient With Psoriasis Vulgaris, Psoriatic Arthritis and Alopecia Universalis Successfully Treated With Tofacitinib and Methotrexate

open access: yesJEADV Clinical Practice, EarlyView.
We present a case of a 31‐year‐old female with alopecia universalis, psoriasis vulgaris, and psoriatic arthritis, who showed poor response to prior treatments. Following the initiation of a combination therapy with tofacitinib and methotrexate, significant improvements in joint pain and hair regrowth were observed.
Jan Nicolai Wagner   +4 more
wiley   +1 more source

Efficacy and Tolerability of Brodalumab in 42 Adult Patients With Moderate to Severe Psoriasis: First French Real‐Life Case Series on Hard‐to‐Treat Areas

open access: yesJEADV Clinical Practice, EarlyView.
In our real‐life study, brodalumab demonstrates clinical efficacy on psoriasis lesions over a median duration of treatment of 4 months, associated with mean reductions of 94.3% for BSA, 93.1% for PASI and 88.0% for PGA. 23 patients no longer had a single lesion at the follow‐up visit.
Marc Perrussel, Bruno Sassolas
wiley   +1 more source

The Impact of Methotrexate on Cardiovascular Outcomes in Psoriasis: A Systematic Review and Meta‐Analysis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Psoriasis is a chronic immune‐mediated inflammatory disease with a global prevalence of 2%–3% and 1.3% in Brazil. It is associated with comorbidities such as obesity, hypertension, and diabetes, all of which contribute to increased cardiovascular risk due to systemic inflammation and endothelial dysfunction.
Tiago A. S. Costa   +2 more
wiley   +1 more source

The Role of the Gut-Joint Axis in the Care of Psoriatic Arthritis: A Two-Sample Bidirectional Mendelian Randomization Study

open access: yesDermatology and Therapy
Introduction Observational studies and clinical trials have supported the association between gut microbiota and psoriatic arthritis. However, the causal link between gut microbiota and psoriatic arthritis is still unclear.
Yihong Gan   +9 more
doaj   +1 more source

IMMUNOPATHOGENESIS OF PSORIASIS AND PSORIATIC ARTHRITIS AND PHARMACOLOGICAL PERSPECTIVES

open access: yesReumatismo, 2011
Psoriasis and psoriatic arthritis are chronic inflammatory disorders resulting from a combination of genetic and environmental factors, though the precise causal agents have not yet been identified. The immune system has a major role in their development
A. Genovese   +4 more
doaj   +1 more source

MACE and VTE across upadacitinib clinical trial programmes in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis. [PDF]

open access: yesRMD Open, 2023
Charles-Schoeman C   +11 more
europepmc   +1 more source

Successful Treatment of Spesolimab in a Haemodialysis Patient With Acutely Flaring Generalised Pustular Psoriasis

open access: yesJEADV Clinical Practice, EarlyView.
Capsule Summary Generalised pustular psoriasis is one of the severe dermatological disorders. The use of biologics in psoriatic patients with end‐stage renal disease is rare, and the safety information on biologics treatment in such patients is limited.
Yasuyuki Fujita   +4 more
wiley   +1 more source

Mortality trends in a Cohort of Canadian Psoriatic Arthritis Patients

open access: yesMcGill Journal of Medicine, 2020
Methods: We reviewed retrospectively the charts of psoriatic arthritis patients who died from 1995-2010.We included 13 deceased patients with a psoriatic arthritis di-agnosis and compared them with 140 patients living with psoriatic arthritis that at ...
Boluwaji Ogunyemi
doaj  

IMAGING OF PSORIATIC ARTHRITIS

open access: yesReumatismo, 2011
Imaging of psoriatic arthritis (PsA) is important for two reasons: the differential diagnosis from other arthritides and the assessment of structural damage that can be inhibited by the new drugs such as the anti-TNFalpha agents. Plain film radiographic findings of peripheral arthritis have been important in elaborating the concept of PsA as a separate
Salvatore D'Angelo   +3 more
openaire   +5 more sources

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