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Arthritis Care &Research, EarlyView.As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox +3 more
wiley +1 more source
BMC Rheumatology, 2022 Background Gout may be associated with an increased incidence of mental health disorders, however, published findings have been limited and inconsistent. Therefore, our objective was to conduct a population-based cohort study to evaluate the incidence of
Alyssa Howren +6 more
doaj +1 more source
Mitochondria as Key Players in the Pathogenesis and Treatment of Rheumatoid Arthritis
Frontiers in Immunology, 2021 Mitochondria are major energy-producing organelles that have central roles in cellular metabolism. They also act as important signalling hubs, and their dynamic regulation in response to stress signals helps to dictate the stress response of the cell ...
Sally A. Clayton +7 more
doaj +1 more source
DAS28: a useful instrument to monitor infliximab treatment in patients with rheumatoid arthritis [PDF]
, 2005 The Disease Activity Score using 28 joint counts (DAS28) has been developed in a cohort of patients with rheumatoid arthritis in which only conventional anti-rheumatic treatments were used. It has extensively been validated to monitor disease activity in
Fransen, Jaap, van Riel, Piet LCM
core +2 more sources
Arthritis Care &Research, EarlyView.Objective Imaging evidence of active sacroiliitis is important for diagnosis, classification, and monitoring of axial spondyloarthritis (axSpA). However, there is no consistent guidance on whether patients should temporarily stop nonsteroidal anti‐inflammatory drugs (NSAIDs) before magnetic resonance imaging (MRI).
Gareth T. Jones +10 more
wiley +1 more source
Distinct fibroblast subsets drive inflammation and damage in arthritis
Nature, 2019 The identification of lymphocyte subsets with non-overlapping effector functions has been pivotal to the development of targeted therapies in immune-mediated inflammatory diseases (IMIDs)1,2. However, it remains unclear whether fibroblast subclasses with
A. Croft +23 more
semanticscholar +1 more source
International Journal of STD & AIDS, 1994 Reactive arthritis (ReA) develops after an infection elsewhere in the body, generally in the genitourinary or intestinal tract. Chlamydia trachomatis, Yersinia enterocolitica, salmonella, shigella, and campylobacter are frequent triggering agents. Between 60% and 90% of patients are positive for HLA-B27.
openaire +3 more sources
Regulation of peripheral inflammation by spinal p38 MAP kinase in rats. [PDF]
, 2006 BackgroundSomatic afferent input to the spinal cord from a peripheral inflammatory site can modulate the peripheral response. However, the intracellular signaling mechanisms in the spinal cord that regulate this linkage have not been defined.
Albani, Salvatore +7 more
core +3 more sources
Time Trends and Predictors of Gout Remission Over 6 Years
Arthritis Care &Research, EarlyView.Objective This study aims to describe the trends in remission rates over 6 years of follow‐up among people with gout taking urate‐lowering therapy (ULT) and to identify variables that predict remission. Methods A post hoc analysis was conducted using data from the Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout (CARES) trial ...
Adwoa Dansoa Tabi‐Amponsah +5 more
wiley +1 more source
Vitamin D and early rheumatoid arthritis
BMC Rheumatology, 2020 Background Previous studies have linked rheumatoid arthritis (RA) risk and disease activity with vitamin D-deficiency (low serum 25-hydroxyvitamin D (25OHD)), but a causal role for vitamin D in RA is still unclear, with conflicting results from many ...
Stephanie R. Harrison +6 more
doaj +1 more source