Results 41 to 50 of about 25,644 (268)

Powerful proteins from polyp possessing predators [PDF]

open access: yes, 2021
Cnidarians are soft bodied animals possessing complex venom systems which have evolved to allow for the capture of arthropod and vertebrate prey, as well as to defend themselves against such predators.
Robinson P.J., Trim, S.A., Trim, C.M.
core  

Mosquito Salivary Proteins and Arbovirus Infection: From Viral Enhancers to Potential Targets for Vaccines

open access: yesPathogens, 2023
Arthropod-borne viruses present important public health challenges worldwide. Viruses such as DENV, ZIKV, and WNV are of current concern due to an increasing incidence and an expanding geographic range, generating explosive outbreaks even in non-endemic ...
Alejandro Marín-López   +5 more
doaj   +1 more source

Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission [PDF]

open access: yes, 2016
BACKGROUND: Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa.
Scoles, Glen A.   +17 more
core   +1 more source

Discovery of a Reversible Sub‐Picomolar Thrombin Inhibitor Using DCC

open access: yesAngewandte Chemie, EarlyView.
An ultrapotent yet fully reversible trivalent thrombin inhibitor discovered through screening a large dynamic combinatorial library (DCL) of 125 000 members of self‐assembled fragments. The innovative approach leverages size‐exclusion‐based affinity selection, coupled with MALDI‐TOF mass spectrometry readout, enabling the full workflow to be completed ...
Millicent Dockerill   +2 more
wiley   +2 more sources

Spider-Venom Peptides as Bioinsecticides

open access: yesToxins, 2012
Over 10,000 arthropod species are currently considered to be pest organisms. They are estimated to contribute to the destruction of ~14% of the world’s annual crop production and transmit many pathogens.
Glenn F. King   +5 more
doaj   +1 more source

Rapid protein profiling for arthropod vector identification [PDF]

open access: yesParasites & Vectors, 2014
Identification of insect vectors is primarily carried out using morphological features, which can be a time-consuming and difficult task. PCR-based approaches have been developed for the identification of a number of vector species. We have recently established matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS),
Mathis, A   +3 more
openaire   +3 more sources

The Unfolded-Protein Response Triggers the Arthropod Immune Deficiency Pathway

open access: yesmBio, 2022
The ability of an arthropod to harbor and transmit pathogens is termed “vector competency.” Many factors influence vector competency, including how arthropod immune processes respond to the microbe. Divergences in innate immunity between arthropods are increasingly being reported.
Lindsay C. Sidak-Loftis   +9 more
openaire   +3 more sources

Managing iron supply during the infection cycle of a flea borne pathogen, Bartonella henselae.

open access: yesFrontiers in Cellular and Infection Microbiology, 2013
Bartonella are hemotropic bacteria responsible for emerging zoonoses. Most Bartonella species appear to share a natural cycle that involves an arthropod transmission, followed by exploitation of a mammalian host in which they cause long-lasting intra ...
Francis eBiville, Ma Feng eLiu
doaj   +1 more source

Immunity against Ixodes scapularis salivary proteins expressed within 24 hours of attachment thwarts tick feeding and impairs Borrelia transmission. [PDF]

open access: yesPLoS ONE, 2007
In North America, the black-legged tick, Ixodes scapularis, an obligate haematophagus arthropod, is a vector of several human pathogens including Borrelia burgdorferi, the Lyme disease agent.
Sukanya Narasimhan   +10 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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