Results 51 to 60 of about 80,150,569 (305)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

From the editor’s desk

open access: yesJournal of Transport and Supply Chain Management
No abstract available.
Stephen Kruger
doaj   +1 more source

AMULETS OF THE “EGYРTIAN” FAIENCE FROM THE TERRITORY OF ROSTOV REGION IN THE PUBLICATION OF LATE XIX - EARLY XXI C.C

open access: yesRUDN Journal of World History, 2017
The article is devoted to the historiographical review of publications dated by late XIX - early XXI centuries and containing information about amulets and talismans of the Egyptian faience, found in the settlements and burial grounds in Rostovskaya ...
S B Burkov, S M-A Gadalrab
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Selenium improves the content of vitamin C in the fruit of strawberry by regulating the enzymes responsible for vitamin C metabolism

open access: yesPlant, Soil and Environment, 2022
To investigate how sodium selenite (Na2SeO3) regulated the content of vitamin C (Vc) in strawberry fruit, we explored the effects of Na2SeO3 on the enzymes responsible for Vc metabolism. The findings showed that 10 mg/L Na2SeO3 improved the activities of
Ninghai Lu   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

St. Thomas Aquinas, Dramatist? [PDF]

open access: yesStudia Gilsoniana, 2016
The article begins with the statement that there is one aspect of St Thomas’s work that has not received due scrutiny as a literary form, one with solid dramatic qualities and structure: the Article.
Eric McLuhan
doaj  

How Can the TPNW Regime Be Sustained?

open access: yesJournal for Peace and Nuclear Disarmament, 2021
Experience in implementing both other WMD treaties and other humanitarian disarmament treaties suggests that the TPNW regime can be effective in building and sustaining a global norm against nuclear weapons, even if no nuclear-armed state joins the ...
Richard Lennane, Richard Moyes
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Home - About - Disclaimer - Privacy