Results 51 to 60 of about 85,976,067 (249)

Modelos ortogonais para a estimativa multivariada de VAR (Value-at-risk) para risco de mercado: um estudo de caso comparativo

open access: yesRevista de Economia Mackenzie, 2011
O presente trabalho tem como objetivo explorar diferentes modelos de estimativa da distribuição conjunta de fatores para risco de mercado, com ênfase nos modelos ortogonais. Foram explorados cinco modelos: 1.
João Luiz Chela   +2 more
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

ÖRGÜTLERDE SİBER ZORBALIK VE İLETİŞİM BECERİLERİ: AKADEMİ ÖRNEĞİ

open access: yesEtkileşim
Bu araştırmada akademisyenlerin siber zorbalık ve iletişim dinamiklerine yönelik görüşleri derinlemesine incelenmiştir. Bu doğrultuda 14 akademisyen ile derinlemesine görüşmeler gerçekleştirilmiştir.
Seda Gökçe TURAN
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Retraction: Metabolism Determination By Soft Computing Methods From Breath Molecules

open access: yesSakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2023
The article whose title is given above was retracted by the decision of the Editorial Board upon the request of the authors.
Ismail Bayraklı   +2 more
doaj  

Definitions and terminology regarding the Romanian article. A diachronic perspective [PDF]

open access: yesDiversitate si Identitate Culturala in Europa, 2022
Analysed from a diachronic perspective in the grammars we have addressed in our work, the Romanian article has determined controversial situations mainly due to the various meanings of the species identified over time and its definitions, and ...
Alina Marieta RUCĂREANU/Nun Alexandra
doaj  

Pediatric Mediastinal Gray Zone Lymphoma With Germline TET2 Heterozygous Variant

open access: yes
Pediatric Blood &Cancer, EarlyView.
Matthew R. Schuelke   +9 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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