Results 71 to 80 of about 57,433,167 (306)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

1972 Oregon Vineyards Directory Article [PDF]

open access: yes, 2015
The \u2772 Oregon Vineyards Directory (as printed in the Roseburg News-Review) features 25 vineyards larger than one acre throughout Oregon. By 1971, 138.2 acres were planted with wine grapes in Oregon, and vineyards projected significant growth for 1972
The News-Review
core   +1 more source

Unusual appearance of a pendulated gastric tumor : always think of GIST [PDF]

open access: yes, 2012
Objective. To investigate the clinicopathological characteristics of gastrointestinal stromal tumor (GIST) with significant cystic changes and to assess the molecular genetic characteristics. Methods.
Anne Hoorens   +5 more
core   +4 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Identifying (In)Definiteness in Vietnamese Noun Phrase

open access: yesJournal of the Southeast Asian Linguistics Society, 2022
This paper aims to settle the issue of whether những, các, một are articles in Vietnamese as argued by Nguyen T. C. (1975), Nguyen H. T. (2004), a.o.
Phan, Trang, Chierchia, Gennaro
doaj  

Bjelland Awaits Anniversary Article [PDF]

open access: yes, 1975
This captioned photo collage from the Roseburg News-Review marks the upcoming fifth anniversary for Bjelland Vineyards on October 12, 1975.
The News-Review
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Reference Citation and writing Bibliography using Mendeley Reference Manager [PDF]

open access: yesPerspectives In Medical Research, 2016
While writing and editing research papers or dissertations, we face difficulties with ● Searching and organising the references in one place, ● Citing and remembering the sequence of references as they appear in our research article, and the final ...
Momin Kashif
doaj  

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