Results 31 to 40 of about 11,137,668 (302)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A Systematic Review of the Characteristics of Articles Published in the Politics Quarterly, Journal of University of Tehran [PDF]

open access: yesمجله علم‌سنجی کاسپین, 2021
Background and aim: One of the main indicators of the development of a science discipline is the scientific outputs and articles. The aim of this study was to investigate the characteristics of articles published in the Politics Quarterly, Journal of ...
Yahya Kamali   +1 more
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Text analysis and reader interaction [PDF]

open access: yes, 1992
EFL teachers from the Brazilian public sector have often experienced difficulties in efficiently accessing the relevant information from articles published in 'English Teaching Forum'. This study attempts to investigate these difficulties from both 'text-
TEFL methods articles,
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Scientometric highlights on Science and Technology review articles affiliated to India [PDF]

open access: yes, 2009
Garfield stated that review articles often serve as surrogates for earlier literature, thus avoiding extensive bibliographies. The present study has focused on the review articles written by researchers in India and included in Science Citation Index ...
Kumar, Vijai   +3 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Research Impact of Open Access Journal Articles [PDF]

open access: yes, 2007
The availability of scientific and intellectual works freely through scientists’ personal web sites, digital university archives or through the electronic print (eprint) archives of major scientific institutions has radically changed the process of ...
Ü. Yurdagül   +5 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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