Results 51 to 60 of about 11,378,651 (289)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Sbottoms of Natural NMSSM at the LHC
, 2016 Search for the bottom squarks (sbottoms) at the Large Hadron Collider (LHC) has recently assumed a heightened focus in the hunt for Supersymmetry (SUSY).
Beuria, Jyotiranjan +2 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Concave univalent functions and Dirichlet finite integral
, 2016 The article deals with the class ${\mathcal F}_{\alpha }$ consisting of non-vanishing functions $f$ that are analytic and univalent in $\ID$ such that the complement $\IC\backslash f(\ID) $ is a convex set, $f(1)=\infty ,$ $f(0)=1$ and the angle at ...
Muhanna, Y. Abu, Ponnusamy, S.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Surjectivity of maps induced on matrices by polynomials and entire functions
, 2016 We determine a necessary and sufficient condition for a polynomial over an algebraically closed field $k$ to induce a surjective map on matrix algebras $M_n(k)$ for $n \ge 2$.
Mondal, Shubhodip
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Imbalanced Ensemble Classifier for learning from imbalanced business school data set
, 2018 Private business schools in India face a common problem of selecting quality students for their MBA programs to achieve the desired placement percentage. Generally, such data sets are biased towards one class, i.e., imbalanced in nature.
Chakraborty, Tanujit
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source