Results 51 to 60 of about 3,186,282 (234)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Литьë и металлургия, 2007 The way of electro-slag casting of the articles ''Heart hornlike'*, used for production of pipe taps under GOST 17375-83 is considered. The expediency of the electro-slag remelt application is shown, the technological parameters and regimes of casting ...
S. N. Zherebtsov
doaj
Evaluative Resources in Medical Research Articles Written by Medical Writers
مجلة الآداب, 2019 Many studies have been presented about the topic of medical researches and articles ,but it has been noticed that the previously mentioned studies haven’t dealt with language usage in terms of attitude and emotional status .
Muna Abdul Hussien Swayer +1 more
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Литьë и металлургия, 2007 The experimental and literature data on characteristics and functions of fluxing agents and slags, applied for running of stable melting processes in different electroslag technologies, are generalized.
S. N. Zherebtsov, M. V. Romanovskij
doaj
Twenty articles in didactics of mathematics by Pranas Mašiotas
Lietuvos Matematikos Rinkinys, 2008 For many years, Pranas Mašiotas (1863–1940) was engaged as a teacher of mathematics, a director of gymnasium and a vice-minister of education. He compiled a number of mathematical manuals for Lithuanian primary and secondary schools.
Algirdas Ažubalis
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Investigations into children's acquisition of the partitive structure
Nordlyd: Tromsø University Working Papers on Language & Linguistics, 2008 Recent literature suggests that children’s acquisition of DP is a process of gradual feature acquisition (Roeper 2006). This study looks at the acquisition of DP’s barrier feature from the perspective of the acquisition of the syntax of the English ...
Helen Stickney
doaj +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source