Results 71 to 80 of about 3,253,670 (325)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Identification of multidisciplinary research based upon dissimilarity analysis of journals included in reference lists of Wageningen University & Research articles [PDF]

open access: yesarXiv, 2018
This paper discusses the identification of journal articles that probably report on multidisciplinary research. Identification of these articles may be important for strategic purposes for the institution where the research is performed or for the evaluation of researchers or groups.
arxiv  

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Earlier Web Usage Statistics as Predictors of Later Citation Impact [PDF]

open access: yesarXiv, 2005
The use of citation counts to assess the impact of research articles is well established. However, the citation impact of an article can only be measured several years after it has been published. As research articles are increasingly accessed through the Web, the number of times an article is downloaded can be instantly recorded and counted. One would
arxiv  

Why articles are retracted: a retrospective cross-sectional study of retraction notices at BioMed Central

open access: yesBMJ Open, 2016
Objectives To assess why articles are retracted from BioMed Central journals, whether retraction notices adhered to the Committee on Publication Ethics (COPE) guidelines, and are becoming more frequent as a proportion of published articles.
E. Moylan, Maria K Kowalczuk
semanticscholar   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

A Social Network Analysis of Articles on Social Network Analysis [PDF]

open access: yesarXiv, 2018
A collection of articles on the statistical modelling and inference of social networks is analysed in a network fashion. The references of these articles are used to construct a citation network data set, which is almost a directed acyclic graph because only existing articles can be cited.
arxiv  

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy