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Fatigue of Articular Cartilage
Nature, 1973IT has been suggested1 that fibrillation, the earliest change in osteoarthritic cartilage visible to the naked eye, may be the result of fatigue failure. Abnormally high stresses in the superficial layer of cartilage could be produced by unusually high applied loads, incongruity of the joint surface, or softening of the cartilage by mucopolysaccharide ...
S. A. V. Swanson +2 more
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Articular cartilage transplantation
Human Pathology, 1977This report describes the biopsy findings in four of 30 patients treated with cadaver osteochondral shell allografts for osteoarthritis in the knee. This study demonstrates that graft cartilage cells can survive in excess of 25 months, and that host bone can completely replace graft bone by creeping substitution.
Joseph B. Houpt +4 more
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Orthopedics, 2008
The morphologic changes of articular cartilage with bone grafting to fill subchondral bone defects were studied in 23-month-old New Zealand rabbits with bilateral tibial subchondral bone defects. The defects were made approximately 5 mm below the articular surface and were covered with surrounding tissues. The right side was filled with calcium sulfate
Sang Weilin, Ma Jinzhong
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The morphologic changes of articular cartilage with bone grafting to fill subchondral bone defects were studied in 23-month-old New Zealand rabbits with bilateral tibial subchondral bone defects. The defects were made approximately 5 mm below the articular surface and were covered with surrounding tissues. The right side was filled with calcium sulfate
Sang Weilin, Ma Jinzhong
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Nanoscale, 2017
The regeneration of articular cartilage, which scarcely shows innate self-healing ability, is a great challenge in clinical treatment. Stem cell-derived exosomes (SC-Exos), an important type of extracellular nanovesicle, exhibit great potential for ...
Xiaolin Liu +9 more
semanticscholar +1 more source
The regeneration of articular cartilage, which scarcely shows innate self-healing ability, is a great challenge in clinical treatment. Stem cell-derived exosomes (SC-Exos), an important type of extracellular nanovesicle, exhibit great potential for ...
Xiaolin Liu +9 more
semanticscholar +1 more source
Microfracture of Articular Cartilage
JBJS Reviews, 2016➢ Microfracture is a treatment option for symptomatic, full-thickness cartilage defects.➢ Microfracture is most likely to be successful when performed in nonobese patients under the age of thirty years for small (<2 to 4-cm2) femoral condylar defects that have been symptomatic for a short time (less than twelve to twenty ...
Timothy E. Hewett +4 more
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Articular cartilage: from formation to tissue engineering.
Biomaterials Science, 2016Hyaline cartilage is the nonlinear, inhomogeneous, anisotropic, poro-viscoelastic connective tissue that serves as friction-reducing and load-bearing cushion in synovial joints and is vital for mammalian skeletal movements.
S. Camarero‐Espinosa +3 more
semanticscholar +1 more source
Clinical Orthopaedics and Related Research, 2002
The acute and repetitive impact and torsional joint loading that occurs during participation in sports can damage articular surfaces causing pain, joint dysfunction, and effusions. In some instances, this articular surface damage leads to progressive joint degeneration. Three classes of chondral and osteochondral injuries can be identified based on the
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The acute and repetitive impact and torsional joint loading that occurs during participation in sports can damage articular surfaces causing pain, joint dysfunction, and effusions. In some instances, this articular surface damage leads to progressive joint degeneration. Three classes of chondral and osteochondral injuries can be identified based on the
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Permeability of Articular Cartilage
Nature, 1968IN 1962, McCutcheon1 first drew attention to a decrease in the permeability of articular cartilage with increasing depth from the surface. This observation has been confirmed2 and the permeability shown to be inversely related to the fixed charge density of the cartilage matrix.
Alice Maroudas, Peter Bullough
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The collagens of articular cartilage
Seminars in Arthritis and Rheumatism, 1991Articular cartilage contains at least five genetically distinct types of collagen. Types II, IX, and XI are cartilage-specific and are cross-linked together in a copolymeric network that forms the extracellular framework of the tissue. Fibrils of type II collagen provide the basic architecture.
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Journal of the American Academy of Orthopaedic Surgeons, 2003
Articular cartilage is a complex tissue maintained by chondrocytes, which undergo metabolic changes as a result of aging, disease, and injury. These changes may hinder tissue maintenance and repair, resulting in accelerated loss of articular surface and leading to end-stage arthritis.
Regis J. O'Keefe +4 more
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Articular cartilage is a complex tissue maintained by chondrocytes, which undergo metabolic changes as a result of aging, disease, and injury. These changes may hinder tissue maintenance and repair, resulting in accelerated loss of articular surface and leading to end-stage arthritis.
Regis J. O'Keefe +4 more
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