Results 61 to 70 of about 1,244,975 (267)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Findings: The Potential Future Risks of AI [PDF]
, 2023 Report explaining some of the potential risks associated with the future of artificial intelligence (AI) advancements to advise the U.S. President and the White House National AI Initiative Office (NAIIO)
National Artificial Intelligence Advisory Committee
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Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
الأُسُسُ الفلسفيةُ والمنطقيةُ للذكاءِ الاصطناعيِّ (دراسة تطبيقية) [PDF]
Mağallaẗ Kulliyyaẗ al-dirāsāt al-islāmiyyaẗ wa al-ʿarabiyyaẗ lil banat bi ğāmiʿaẗ Al-Ahzhar farʿ kafr Al-Sheikhتهدف هذه الدراسة إلى بيان أن كلًا من الفلسفة والمنطق ما زالا هما المحركان لكافة أشكال التفكير لا سيما في هذا العصر، وأن التصنيف الفلسفي للأفكار يساعد على استيضاح المآلات والتعامل معها.
محمد السيد عبد الحميد والي
doaj +1 more source
Artificial Intelligence Approaches to Medical Diagnosis [PDF]
, 1974 Work reported herein was conducted at the Artificial Intelligence Laboratory, a Massachusetts Institute of Technology research program supported in part by the Advanced Research Projects Agency of the Department of Defense and monitored by the Office of ...
Rubin, Andee
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FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
The Limits of Information Science: Limits of Aims, Processes and Results
Artefactos, 2020 The problem of information science can be analyzed following several steps. First, there is the issue of the angle of analysis, which can be oriented in two directions: a) to consider information science from the viewpoint of its boundaries as scientific
Antonio BEREIJO
doaj +1 more source
Levins and the lure of artificial worlds
, 2014 What is it about simulation models that has led some practitioners to treat them as potential sources of empirical data on the real-world systems being simulated; that is, to treat simulations as ‘artificial worlds’ within which to perform computational ‘
Bullock, Seth
core +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source