Results 51 to 60 of about 2,868,919 (307)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Learning models of sequential decision-making with partial specification of agent behavior

open access: yes, 2019
Artificial agents that interact with other (human or artificial) agents require models in order to reason about those other agents’ behavior. In addition to the predictive utility of these models, maintaining a model that is aligned with an agent’s true ...
Shah, Julie A.   +3 more
core   +1 more source

Injectable Bulking Agents for Urinary Incontinence after Radical Prostatectomy, Mimicking Local Recurrence: A Case Report

open access: yes대한영상의학회지, 2017
Periurethral bulking agent injection (or transurethral submucosal injection) is a comparatively less invasive procedure for the treatment of stress urinary incontinence in patients who develop incontinence after radical prostatectomy, and who are more ...
Jehong Yoon   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Using Cultures and Values to Support Flexible Coordination [PDF]

open access: yes, 2015
This thesis proposes a method for supporting flexible coordination in multi-agent systems (MASs). In other words, we aim at influencing societies of artificial agents such that they can handle complex and evolving environments and collective goals ...
Sub Algemeen Artificial Intelligence   +2 more
core  

Findings: The Potential Future Risks of AI [PDF]

open access: yes, 2023
Report explaining some of the potential risks associated with the future of artificial intelligence (AI) advancements to advise the U.S. President and the White House National AI Initiative Office (NAIIO)
National Artificial Intelligence Advisory Committee
core  

Atrial Standstill: a Rare Case

open access: yesJournal of Tehran University Heart Center, 2011
We introduce a 32-year-old man who was evaluated for a dizziness and headache of unknown origin for at least two months and was referred to our center after ECG findings.
Ahmad Yaminisharif   +3 more
doaj  

Estimulação cardíaca artificial em pacientes portadores de cardiomiopatia hipertrófica: uma coorte com 24 anos de seguimento Cardiac pacing in hypertrophic cardiomyopathy: a cohort with 24 years of follow-up

open access: yesArquivos Brasileiros de Cardiologia, 2008
FUNDAMENTO: O benefício da estimulação cardíaca em pacientes portadores de cardiomiopatia hipertrófica (CMH) tem sido questionado, sendo escassas as pesquisas sobre este assunto no Brasil.
Lenine Angelo Alves Silva   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Metaphysics of Design

open access: yesDIID
The paper is concerned with beginning to lay a basis for a more comprehensive model of designing, one that can overcome the abyss between the conceptual limitations of purely professional designing and wider instincts of design capabilities.
Clive Dilnot
doaj   +1 more source

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