Results 81 to 90 of about 6,877,980 (390)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The Artificial Intelligence Course at the Faculty of Computer Science in the Polytechnic University of Madrid [PDF]

open access: yes, 1994
This paper presents the experience of teaching an Artificial Intelligence course at the Faculty of Computer Science in the Polytechnic University of Madrid, Spain.
Gómez-Pérez, A., Juristo, N.
core   +1 more source

Observation of Light Guiding by Artificial Gauge Fields

open access: yes, 2018
The use of artificial gauge fields enables systems of uncharged particles to behave as if affected by external fields. Generated by geometry or external modulation, artificial gauge fields have been instrumental in demonstrating topological phenomena in ...
Bandres, Miguel A.   +6 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Transit Lightcurve Signatures of Artificial Objects [PDF]

open access: yes, 2005
The forthcoming space missions, able to detect Earth-like planets by the transit method, will a fortiori also be able to detect the transit of artificial planet-size objects.
Luc F. A. Arnold, Tarter J.
core   +3 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Automatic Programming of Cellular Automata and Artificial Neural Networks Guided by Philosophy

open access: yes, 2020
Many computer models such as cellular automata and artificial neural networks have been developed and successfully applied. However, in some cases, these models might be restrictive on the possible solutions or their solutions might be difficult to ...
A Ilachinski   +9 more
core   +1 more source

Artificial Neural Networks in Medical Diagnosis

open access: yesInternational Journal of Research Publication and Reviews
Artificial neural networks are finding many uses in the medical diagnosis application. The goal of this paper is to evaluate artificial neural network in disease diagnosis. Two cases are studied.
Qeethara Al-Shayea
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

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