Results 31 to 40 of about 516,542 (265)
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Urban-E: Satellite-based Urban and Environmental Change Analysis in Egypt with Deep Learning
International Journal of Computational Intelligence SystemsThe detection of urban and environmental change using satellite imagery is crucial for urban planning, sustainable development, and environmental monitoring.
Amany M. Sarhan +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Inferring strategies from observations in long iterated Prisoner’s dilemma experiments
Scientific Reports, 2022 While many theoretical studies have revealed the strategies that could lead to and maintain cooperation in the Iterated Prisoner’s dilemma, less is known about what human participants actually do in this game and how strategies change when being ...
Eladio Montero-Porras +3 more
doaj +1 more source
GHOST—A New Face Swap Approach for Image and Video Domains
IEEE Access, 2022 Deep fake stands for a face swapping algorithm where the source and target can be an image or a video. Researchers have investigated sophisticated generative adversarial networks (GAN), autoencoders, and other approaches to establish precise and robust ...
Alexander Groshev +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Optimized Phased Antenna Array for Deep-Targeted Microwave Hyperthermia in Brain Tumor Therapy
Concepts in Magnetic Resonance: Part A, Bridging Education and ResearchThis study develops an optimized personalized microwave hyperthermia framework for glioblastoma treatment, integrating a 19-channel radiofrequency array of geometrically and electromagnetically co-optimized cosine-curved dipole antennas. We initiated the
Haode Wang +3 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
ACE2: accurately learning subseasonal to decadal atmospheric variability and forced responses
npj Climate and Atmospheric ScienceExisting machine learning models of weather variability are not formulated to enable assessment of their response to varying external boundary conditions such as sea surface temperature and greenhouse gases.
Oliver Watt-Meyer +8 more
doaj +1 more source