Results 31 to 40 of about 1,874,578 (291)
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Egyptian car plate recognition based on YOLOv8, Easy-OCR, and CNN
This research presents an innovative approach to Egyptian car plate recognition using YOLOv8 and optical character recognition (OCR) technologies. Leveraging the powerful object detection capabilities of YOLOv8, the system efficiently detects car plates ...
Amany Sarhan +7 more
doaj +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Skin cancer, particularly melanoma, poses a critical global health challenge due to its high mortality rate. Early and precise detection is vital for effective treatment and better prognosis.
Amany M. Sarhan +6 more
doaj +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Integrating machine learning and sentiment analysis in movie recommendation systems
The fast growth of the film business, along with an ever-increasing number of movie options, has highlighted the need for better recommendation algorithms.
Amany M. Sarhan +5 more
doaj +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Urban-E: Satellite-based Urban and Environmental Change Analysis in Egypt with Deep Learning
The detection of urban and environmental change using satellite imagery is crucial for urban planning, sustainable development, and environmental monitoring.
Amany M. Sarhan +5 more
doaj +1 more source
GHOST—A New Face Swap Approach for Image and Video Domains
Deep fake stands for a face swapping algorithm where the source and target can be an image or a video. Researchers have investigated sophisticated generative adversarial networks (GAN), autoencoders, and other approaches to establish precise and robust ...
Alexander Groshev +4 more
doaj +1 more source

