Results 41 to 50 of about 1,874,578 (291)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Inferring strategies from observations in long iterated Prisoner’s dilemma experiments

open access: yesScientific Reports, 2022
While many theoretical studies have revealed the strategies that could lead to and maintain cooperation in the Iterated Prisoner’s dilemma, less is known about what human participants actually do in this game and how strategies change when being ...
Eladio Montero-Porras   +3 more
doaj   +1 more source

Artificial intelligence: opportunities and implications for the future of decision making [PDF]

open access: yes, 2016
Artificial intelligence has arrived. In the online world it is already a part of everyday life, sitting invisibly behind a wide range of search engines and online commerce sites.
Government, U. K., Science, Office for
core  

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Optimized Phased Antenna Array for Deep-Targeted Microwave Hyperthermia in Brain Tumor Therapy

open access: yesConcepts in Magnetic Resonance: Part A, Bridging Education and Research
This study develops an optimized personalized microwave hyperthermia framework for glioblastoma treatment, integrating a 19-channel radiofrequency array of geometrically and electromagnetically co-optimized cosine-curved dipole antennas. We initiated the
Haode Wang   +3 more
doaj   +1 more source

Asymptotically Unambitious Artificial General Intelligence

open access: yes, 2020
General intelligence, the ability to solve arbitrary solvable problems, is supposed by many to be artificially constructible. Narrow intelligence, the ability to solve a given particularly difficult problem, has seen impressive recent development ...
Cohen, Michael K   +2 more
core   +1 more source

Creativity and artificial intelligence [PDF]

open access: yesArtificial Intelligence, 1998
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

ACE2: accurately learning subseasonal to decadal atmospheric variability and forced responses

open access: yesnpj Climate and Atmospheric Science
Existing machine learning models of weather variability are not formulated to enable assessment of their response to varying external boundary conditions such as sea surface temperature and greenhouse gases.
Oliver Watt-Meyer   +8 more
doaj   +1 more source

Fast Backprojection Filtration Algorithm in Circular Cone-Beam Computed Tomography

open access: yesInternational Journal of Optics, 2023
In order to meet the heavy backprojection calculation of the backprojection filtration (BPF) algorithm in circular cone-beam computed tomography (CT), a fast backprojection method is developed, which uses the integral operator of the fixed scanning angle
Xianchao Wang   +3 more
doaj   +1 more source

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