Results 61 to 70 of about 8,673,646 (306)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Artificial Life of Agents [PDF]

open access: yes, 1996
The research in virtual reality initiated by Carl Eugene Loeffler, Research Director at SIMLAB, NASA/Robotics Engineering Consortium, Carnegie Mellon University, investigates existence within networked simulation environments. To date research efforts have been conducted in the area of tele-existence, where multiple users share or co-inhabit a common ...
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Living Things Are Not (20th Century) Machines: Updating Mechanism Metaphors in Light of the Modern Science of Machine Behavior

open access: yesFrontiers in Ecology and Evolution, 2021
One of the most useful metaphors for driving scientific and engineering progress has been that of the “machine.” Much controversy exists about the applicability of this concept in the life sciences.
Joshua Bongard   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Role of Artificial Intelligence Applications in Real-Life Clinical Practice: Systematic Review

open access: yesJournal of Medical Internet Research, 2020
Background Artificial intelligence (AI) applications are growing at an unprecedented pace in health care, including disease diagnosis, triage or screening, risk analysis, surgical operations, and so forth.
Jiamin Yin, K. Ngiam, H. Teo
semanticscholar   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Effects of Anticipation in Individually Motivated Behaviour on Survival and Control in a Multi-Agent Scenario with Resource Constraints

open access: yesEntropy, 2014
Self-organization and survival are inextricably bound to an agent’s ability to control and anticipate its environment. Here we assess both skills when multiple agents compete for a scarce resource.
Christian Guckelsberger, Daniel Polani
doaj   +1 more source

Effects of Sinusoidal Vibrations on the Motion Response of Honeybees

open access: yesFrontiers in Physics, 2021
Vibratory signals play a major role in the organization of honeybee colonies. Due to the seemingly chaotic nature of the mechano-acoustic landscape within the hive, it is difficult to understand the exact meaning of specific substrate-borne signals ...
Martin Stefanec   +4 more
doaj   +1 more source

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