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Synthetic biology [PDF]

open access: yesOrg. Biomol. Chem., 2010
There is currently much excitement surrounding the rapidly growing discipline of synthetic biology, which utilizes the design and construction principles of engineering to develop, evolve and standardize biological components and systems. This systematic approach to improving and increasing the programmability and robustness of biological components is
Ali Tavassoli, Tavassoli, Ali
openaire   +3 more sources

Synthetic biology—putting engineering into biology [PDF]

open access: yesBioinformatics, 2006
Abstract Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we review the case for this emerging discipline.
Matthias Heinemann, Sven Panke
openaire   +6 more sources

A case study in model-driven synthetic biology [PDF]

open access: yes, 2008
We report on a case study in synthetic biology, demonstrating the modeldriven design of a self-powering electrochemical biosensor. An essential result of the design process is a general template of a biosensor, which can be instantiated to be adapted ...
Trybiło, M   +5 more
core   +7 more sources

Synthetic biology [PDF]

open access: yesNature Reviews Genetics, 2005
Chemistry is a broadly powerful discipline in contemporary science because it has the ability to create new forms of the matter that it studies. By doing so, chemistry can test models that connect molecular structure to behaviour without having to rely on what nature has provided.
Benner, Steven A., Sismour, A. Michael
openaire   +3 more sources

Biosensor-driven, model-based optimization of the orthogonally expressed naringenin biosynthesis pathway

open access: yesMicrobial Cell Factories, 2022
Background The rapidly expanding synthetic biology toolbox allows engineers to develop smarter strategies to tackle the optimization of complex biosynthetic pathways.
Maarten Van Brempt   +6 more
doaj   +1 more source

Dynamic feedback regulation for efficient membrane protein production using a small RNA-based genetic circuit in Escherichia coli

open access: yesMicrobial Cell Factories, 2022
Background Membrane proteins (MPs) are an important class of molecules with a wide array of cellular functions and are part of many metabolic pathways.
Chiara Guidi   +6 more
doaj   +1 more source

Functional Synthetic Biology

open access: yesSynthetic Biology, 2023
AbstractSynthetic biologists have made great progress over the past decade in developing methods for modular assembly of genetic sequences and in engineering biological systems with a wide variety of functions in various contexts and organisms.
Ibrahim Aldulijan   +12 more
openaire   +4 more sources

Analysis of the Innovation Trend in Cell-Free Synthetic Biology [PDF]

open access: yes, 2021
Cell-free synthetic biology is a maturing field that aims to assemble biomolecular reactions outside cells for compelling applications in drug discovery, metabolic engineering, biomanufacturing, diagnostics, and education.
Conary Meyer   +11 more
core   +1 more source

Synthetic biology of hypoxia [PDF]

open access: yesNew Phytologist, 2020
SummarySynthetic biology can greatly aid the investigation of fundamental regulatory mechanisms and enable their direct deployment in the host organisms of choice. In the field of plant hypoxia physiology, a synthetic biology approach has recently been exploited to infer general properties of the plant oxygen sensing mechanism, by expression of plant ...
Licausi, Francesco, Giuntoli, Beatrice
openaire   +4 more sources

Shaping the science-industry-policy interface in synthetic biology

open access: yes, 2022
S.109-114Current advances in the emerging field of synthetic biology and the improvements in key technologies promise great impacts, not only on future scientific development, but also on the economy.
Gaisser, S., Reiß, T.
core   +1 more source

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