Results 31 to 40 of about 934,952 (299)

"Poppy" yeast [PDF]

open access: yes, 2015
I am old enough to have taken part in the international project to sequence the first eukaryotic genome—that of Saccharomyces cerevisiae—which was released in 1996. Twenty years later, scientists from academic and commercial institutions are now involved
RINALDI, Teresa
core   +1 more source

Synthetic Biology: A Bridge between Artificial and Natural Cells. [PDF]

open access: yes, 2014
Artificial cells are simple cell-like entities that possess certain properties of natural cells. In general, artificial cells are constructed using three parts: (1) biological membranes that serve as protective barriers, while allowing communication ...
Ding, Yunfeng, Tan, Cheemeng, Wu, Fan
core   +2 more sources

Plant chemical genetics : from phenotype-based screens to synthetic biology [PDF]

open access: yes, 2017
The treatment of a biological system with small molecules to specifically perturb cellular functions is commonly referred to as chemical biology. Small molecules are used commercially as drugs, herbicides, and fungicides in different systems, but in ...
Dejonghe, Wim, Russinova, Eugenia
core   +3 more sources

Regulation of protein secretion through chemical regulation of endoplasmic reticulum retention signal cleavage

open access: yesNature Communications, 2022
Secreted proteins, such as hormones or cytokines, are key mediators in multicellular organisms. Here the authors present two genetically encoded orthogonal regulatory secretion systems that enables inducible protein release and construction of logic ...
Arne Praznik   +8 more
doaj   +1 more source

Deconstructing synthetic biology across scales: a conceptual approach for training synthetic biologists

open access: yesNature Communications
Synthetic biology allows us to reuse, repurpose, and reconfigure biological systems to address society’s most pressing challenges. Developing biotechnologies in this way requires integrating concepts across disciplines, posing challenges to educating ...
Ashty S. Karim   +16 more
doaj   +1 more source

Genome-scale model of C. autoethanogenum reveals optimal bioprocess conditions for high-value chemical production from carbon monoxide

open access: yesEngineering Biology, 2019
Clostridium autoethanogenum is an industrial microbe used for the commercial-scale production of ethanol from carbon monoxide. While significant progress has been made in the attempted diversification of this bioprocess, further improvements are ...
Rupert O.J. Norman   +13 more
doaj   +1 more source

Molecular Imaging in Synthetic Biology, and Synthetic Biology in Molecular Imaging [PDF]

open access: yes, 2017
Biomedical synthetic biology is an emerging field in which cells are engineered at the genetic level to carry out novel functions with relevance to biomedical and industrial applications.
Gilad, Assaf A., Shapiro, Mikhail G.
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Progression in the In Vitro Macrophage Expansion

open access: yesJournal of Immunology Research
Macrophages play essential roles in homeostasis and disease, and they were considered terminally differentiated cells that cannot proliferate. However, growing evidence shows that macrophages can self-renew in homeostasis and multiple pathological states
Yunpeng Wei   +4 more
doaj   +1 more source

Insights into the Functions, Characteristics, and Mechanisms of Disease-Related Proteins from Akkermansia muciniphila: A Review

open access: yesMicroorganisms
As a representative next-generation probiotic, Akkermansia muciniphila (A. muciniphila) produces a variety of functional proteins that play critical roles in the prevention and treatment of multiple diseases, including metabolic disorders, inflammatory ...
Yanping Han   +7 more
doaj   +1 more source

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