Results 51 to 60 of about 3,570,847 (308)
Rank-guided learning accelerates automated enzyme engineering
Nature CommunicationsEnzyme catalysis has become a cornerstone of modern synthesis, offering sustainable routes to structurally complex molecules. However, the rugged fitness landscape and limited model capacity to learn from sparse data constrain the development of ...
Jingyi Xu +5 more
doaj +1 more source
Construction of microbial systems for polyethylene terephthalate degradation
Synthetic and Systems BiotechnologyPolyethylene terephthalate (PET) is one of the most widely used plastic materials, and its large-scale application has caused severe environmental pollution.
Dingkun He +3 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Can synthetic biology shed light on the origin of life? [PDF]
, 2009 It is a most commonly accepted hypothesis that life originated from inanimate matter, somehow being a synthetic product of organic aggregates, and as such, a result of some sort of prebiotic synthetic biology.
Malaterre, Christophe
core
Synthetic Biology Open Language (SBOL) Version 2.2.0. [PDF]
, 2018 Synthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems.
Misirli
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
The economics of synthetic biology
Molecular Systems Biology, 2007 Mol Syst Biol. 3: 117 Ten years ago, genetic engineering was limited to cutting and pasting DNA from existing organisms. Today's biologists can write down gene sequences that have never existed anywhere, place an order over the Internet, and receive the desired DNA by return mail.
Henkel, Joachim, Maurer, Stephen M
openaire +2 more sources
Trends in Plant Science, 2015 Plant synthetic biology is an emerging field that combines engineering principles with plant biology toward the design and production of new devices. This emerging field should play an important role in future agriculture for traditional crop improvement, but also in enabling novel bioproduction in plants. In this review we discuss the design cycles of
Wusheng, Liu, C Neal, Stewart
openaire +2 more sources
Biotechnology for Biofuels and BioproductsBackground Artificial microbial consortium has been widely employed to improve the production of fengycin, a natural lipopeptide. Kinetic models are essential for understanding and predicting the dynamic behavior of metabolic systems, especially ...
Shi-Long Jin +10 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source