Results 41 to 50 of about 3,570,847 (308)

Modular synthetic biology toolkit for filamentous fungi [PDF]

, 2021
Filamentous fungi are highly productive cell factories, often used in industry for the production of enzymes and small bioactive compounds. Recent years have seen an increasing number of synthetic-biology-based applications in fungi, emphasizing the need
Nyg\ue5rd, Yvonne, M\uf3zsik, L\ue1szl\uf3, Driessen, Arnold J M, Mózsik, László; id_orcid, Bovenberg, Roel A.L., Driessen, Arnold J. M., Bovenberg, Roel A L, Pohl, Carsten, Nygård, Yvonne, Mózsik, László, Nygård, Yvonne; id_orcid, Mózsik, László,, Meyer, Vera,, Pohl, Carsten,, Bovenberg, Roel A. L., Bovenberg, R. A. L., Meyer, Vera, Bovenberg, R. A. L.,, Driessen, Arnold J.M., Driessen, Arnold J.M.,, Nygård, Yvonne,, Yvonne Nygård, Carsten Pohl, Arnold J. M. Driessen, László Mózsik, Roel A. L. Bovenberg, Vera Meyer   +26 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Varieties of Noise: Analogical Reasoning in Synthetic Biology [PDF]

, 2013
The picture of synthetic biology as a kind of engineering science has largely created the public understanding of this novel field, covering both its promises and risks.
Knuuttila, Tarja, Loettgers, Andrea
core  

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The Transnational Governance of Synthetic Biology: Scientific uncertainty, cross-borderness and the ‘art’ of governance. For the Royal Society Science Policy Centre (UK). [PDF]

, 2011
Synthetic biology is a new field of research that aims to 'make biology easier to engineer'. Some claim that it could revolutionise biotechnology to deliver applications for the energy, medical and agricultural sectors. However there are concerns about
Zhang, Joy Yueyue, Rose, Nikolas, Rose, N., Marris, C., Marris, Claire, Zhang, J., Zhang, Joy Y.   +6 more
core  

Developments in the use of microfluidics in synthetic biology

, 2022
Biomimetics aims to copy and imitate natural elements and systems in a simpler form to overcome the limitations of complex biological elements and systems.
Damiati, Safa A.,, Samar Damiati, Laila A. Damiati, Damiati, Laila A.,, Safa A. Damiati, Damiati, Samar,   +5 more
core   +1 more source

DNA-BOT: a low-cost, automated DNA assembly platform for synthetic biology [PDF]

, 2020
Multi-part DNA assembly is the physical starting point for many projects in Synthetic and Molecular Biology. The ability to explore a genetic design space by building extensive libraries of DNA constructs is essential for creating programmed biological ...
Haines, Matthew C, Storch, Marko, Baldwin, Geoff S   +2 more
core   +1 more source

Creation of a eukaryotic multiplexed site-specific inversion system and its application for metabolic engineering

Nature Communications
The site-specific recombination system is a versatile tool in genome engineering, enabling controlled DNA inversion or deletion at specific sites to generate genetic diversity.
Jieyi Li, Simiao Gong, Yuan Ma, Peiyan Han, Nan Wang, Zongheng Fu, Xinyi Zhang, Xinyang Huang, Tianyu Yang, Hanze Tong, Guang-Rong Zhao, Yi Wu, Ying-Jin Yuan   +12 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Toward the first data acquisition standard in synthetic biology [PDF]

, 2016
This paper describes the development of a new data acquisition standard for synthetic biology. This comprises the creation of a methodology that is designed to capture all the data, metadata, and protocol information associated with biopart ...
Bultelle, M, Sainz de Murieta, I, Kitney, RI, Richard I Kitney (2225026), Iñaki Sainz de Murieta, Matthieu Bultelle (2225029), Matthieu Bultelle, Iñaki Sainz de Murieta (2225032), Richard I Kitney   +8 more
core   +1 more source