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Synthetic Biology Open Language (SBOL) Version 2.3. [PDF]
Synthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems.
Misirli
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Synthetic biology: biology by design
Synthetic biology can be defined as the design and construction of novel biologically based parts, devices and systems, as well as the redesign of existing natural biological systems, for useful purposes. It builds on genetic engineering, being design-driven genetic engineering encompassing engineering concepts of standardization and abstraction (Endy,
Roberts, MAJ +3 more
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Principles of synthetic biology [PDF]
Abstract In synthetic biology, biological cells and processes are dismantled and reassembled to make novel systems that do useful things. Designs are encoded by deoxyribonucleic acid (DNA); DNA makes biological (bio-)parts; bioparts are combined to make devices; devices are built into biological systems.
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Emerging Threats of Synthetic Biology and Biotechnology [PDF]
Synthetic biology is a field of biotechnology that is rapidly growing in various applications, such as in medicine, environmental sustainability, and energy production.
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Principles of synthetic biology: a MOOC for an emerging field
Synthetic biology requires students and scientists to draw upon knowledge and expertise from many disciplines. While this diversity is one of the field’s primary strengths, it also makes it challenging for newcomers to acquire the background knowledge ...
Weiss, Ron +2 more
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Genomics and synthetic biology as a viable option to intensify sustainable use of biodiversity [PDF]
The Amazon basin is an area of mega-biodiversity. Different models have been proposed^1-8^ for the establishment of an effective conservation policy, increasing sustainability and adding value for biodiversity. Currently, a broad spectrum of technologies
Elibio Rech +2 more
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Molecular and biochemical characterization of a novel isoprene synthase from Metrosideros polymorpha
Background Isoprene is a five-carbon chemical that is an important starting material for the synthesis of rubber, elastomers, and medicines. Although many plants produce huge amounts of isoprene, it is very difficult to obtain isoprene directly from ...
Soo-Jin Yeom +8 more
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Models for synthetic biology [PDF]
Synthetic biological engineering is emerging from biology as a distinct discipline based on quantification. The technologies propelling synthetic biology are not new, nor is the concept of designing novel biological molecules. What is new is the emphasis on system behavior.
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Synthetic Biology of Antimicrobial Discovery
Antibiotic discovery has a storied history. From the discovery of penicillin by Sir Alexander Fleming to the relentless quest for antibiotics by Selman Waksman, the stories have become like folklore used to inspire future generations of scientists ...
Zakeri, Bijan, Lu, Timothy K.
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Inducible expression of large gRNA arrays for multiplexed CRISPRai applications
CRISPR gene activation and inhibition has become a powerful synthetic tool for influencing the expression of native genes for foundational studies, cellular reprograming, and metabolic engineering.
William M. Shaw +7 more
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