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Developments in the tools and methodologies of synthetic biology. [PDF]
Synthetic biology is principally concerned with the rational design and engineering of biologically based parts, devices, or systems. However, biological systems are generally complex and unpredictable, and are therefore, intrinsically difficult to ...
Freemont, P +3 more
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Grounding knowledge and normative valuation in agent-based action and scientific commitment [PDF]
Philosophical investigation in synthetic biology has focused on the knowledge-seeking questions pursued, the kind of engineering techniques used, and on the ethical impact of the products produced.
A Clark +50 more
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“Cell-Free Synthetic Biology”: Synthetic Biology Meets Cell-Free Protein Synthesis
Since Nirenberg and Matthaei used cell-free protein synthesis (CFPS) to elucidate the genetic code in the early 1960s [...]
Seok Hoon Hong
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Synthetic biology and microdevices : a powerful combination [PDF]
Recent developments demonstrate that the combination of microbiology with micro-and nanoelectronics is a successful approach to develop new miniaturized sensing devices and other technologies.
Marchal, Kathleen +2 more
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Editorial–Synthetic Biology [PDF]
Synthetic biology builds upon over 35 years of genetic engineering. For example, in the 1970s methods were invented for using enzymes to rework DNA. Applying these tools, bacteria were engineered to yield relevant products such as growth hormones and insulin.
Collins, James J. +3 more
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Synthetic biology's flywheel [PDF]
Producing drugs and chemicals efficiently from cells remains a major challenge. Synthetic biologists need to invent the equivalents of the crank and flywheel to improve productivity.
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Plant synthetic biology is an emerging field that combines engineering principles with plant biology toward the design and production of new devices. This emerging field should play an important role in future agriculture for traditional crop improvement, but also in enabling novel bioproduction in plants. In this review we discuss the design cycles of
Wusheng, Liu, C Neal, Stewart
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Chemical communication between synthetic and natural cells: a possible experimental design [PDF]
The bottom-up construction of synthetic cells is one of the most intriguing and interesting research arenas in synthetic biology. Synthetic cells are built by encapsulating biomolecules inside lipid vesicles (liposomes), allowing the synthesis of one or ...
D'Angelo, Francesca +5 more
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Although both the most popular form of synthetic biology (SB) and chemical synthetic biology (CSB) share the biotechnologically useful aim of making new forms of life, SB does so by using genetic manipulation of extant microorganism, while CSB utilises classic chemical procedures in order to obtain biological structures which are non-existent in ...
CHIARABELLI, Cristiano, Luisi P.L.
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‘Can Simple Biological Systems be Built from Standardized Interchangeable Parts?’:Negotiating Biology and Engineering in a Synthetic Biology Competition [PDF]
Synthetic biology represents a recent attempt to bring engineering principles and practices to working with biology. In practice, the nature of the relationship between engineering and biology in synthetic biology is a subject of ongoing debate.
Calvert, Jane, Frow, Emma
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