Results 11 to 20 of about 2,683,742 (306)
“Cell-Free Synthetic Biology”: Synthetic Biology Meets Cell-Free Protein Synthesis
Since Nirenberg and Matthaei used cell-free protein synthesis (CFPS) to elucidate the genetic code in the early 1960s [...]
Seok Hoon Hong
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A synthetic transcription platform for programmable gene expression in mammalian cells
Precise and scalable regulation of gene expression in mammalian cells is challenging. Here, the authors created a highly tunable CRISPR-based synthetic transcription system for programmable control of mammalian gene expression and cellular activity.
William C. W. Chen +13 more
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The development of synthetic biology: A patent analysis
S.209-220In the past decades, synthetic biology has gained interest regarding research and development efforts within the biotechnology domain.
Reiß, T. +2 more
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Synthetic biology of fungal natural products [PDF]
This work was supported by the DFG-funded excellence graduate school Jena School for Microbial Communication (JSMC; DJM, AAB), the collaborative research center (SFB) 1127 Chemical Mediators in Complex Biosystems (ChemBioSys—AAB, project B02) and the ...
Vito Valiante +7 more
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Pictures of Synthetic Biology [PDF]
This article is concerned with the representation of Synthetic Biology in the media and by biotechnology experts. An analysis was made of German-language media articles published between 2004 and 2008, and interviews with biotechnology-experts at the ...
Seiringer, Alexandra +3 more
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Aptamers, Riboswitches, and Ribozymes in S. cerevisiae Synthetic Biology
Among noncoding RNA sequences, riboswitches and ribozymes have attracted the attention of the synthetic biology community as circuit components for translation regulation.
Huanhuan Ge, Mario Andrea Marchisio
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Synthetic Genomes for Synthetic Biology [PDF]
A genome synthesized entirely from scratch has been used to replace the native genome of a living cell, thus creating a new cell. This achievement marks a new frontier in synthetic biology to design and create genomes for organisms with few genetic tools and for applications in areas of energy, health care and the environment.
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Synthetic biology's flywheel [PDF]
Producing drugs and chemicals efficiently from cells remains a major challenge. Synthetic biologists need to invent the equivalents of the crank and flywheel to improve productivity.
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A synthetic microbial biosensor for high-throughput screening of lactam biocatalysts
Efficient biosynthesis of lactams is still undesirable due to lacking of suitable enzyme. Here, the authors develop a sensitive transcription factor-based biosensor for high-throughput screening of marine metagenome and find a cyclase that can cyclize ω ...
Soo-Jin Yeom +10 more
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Although both the most popular form of synthetic biology (SB) and chemical synthetic biology (CSB) share the biotechnologically useful aim of making new forms of life, SB does so by using genetic manipulation of extant microorganism, while CSB utilises classic chemical procedures in order to obtain biological structures which are non-existent in nature.
CHIARABELLI, Cristiano, Luisi P.L.
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