Results 11 to 20 of about 427,199 (265)
Chemistry is a broadly powerful discipline in contemporary science because it has the ability to create new forms of the matter that it studies. By doing so, chemistry can test models that connect molecular structure to behaviour without having to rely on what nature has provided.
Benner, Steven A., Sismour, A. Michael
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AbstractSynthetic biologists have made great progress over the past decade in developing methods for modular assembly of genetic sequences and in engineering biological systems with a wide variety of functions in various contexts and organisms.
Ibrahim Aldulijan +12 more
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Synthetic biology—putting engineering into biology [PDF]
Abstract Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we review the case for this emerging discipline.
Matthias Heinemann, Sven Panke
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There is currently much excitement surrounding the rapidly growing discipline of synthetic biology, which utilizes the design and construction principles of engineering to develop, evolve and standardize biological components and systems. This systematic approach to improving and increasing the programmability and robustness of biological components is
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Synthetic Genomes for Synthetic Biology [PDF]
A genome synthesized entirely from scratch has been used to replace the native genome of a living cell, thus creating a new cell. This achievement marks a new frontier in synthetic biology to design and create genomes for organisms with few genetic tools and for applications in areas of energy, health care and the environment.
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Synthetic biology's flywheel [PDF]
Producing drugs and chemicals efficiently from cells remains a major challenge. Synthetic biologists need to invent the equivalents of the crank and flywheel to improve productivity.
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Although both the most popular form of synthetic biology (SB) and chemical synthetic biology (CSB) share the biotechnologically useful aim of making new forms of life, SB does so by using genetic manipulation of extant microorganism, while CSB utilises classic chemical procedures in order to obtain biological structures which are non-existent in nature.
CHIARABELLI, Cristiano, Luisi P.L.
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Synthetic biology: biology by design
Synthetic biology can be defined as the design and construction of novel biologically based parts, devices and systems, as well as the redesign of existing natural biological systems, for useful purposes. It builds on genetic engineering, being design-driven genetic engineering encompassing engineering concepts of standardization and abstraction (Endy,
Roberts, MAJ +3 more
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Plant synthetic biology is an emerging field that combines engineering principles with plant biology toward the design and production of new devices. This emerging field should play an important role in future agriculture for traditional crop improvement, but also in enabling novel bioproduction in plants. In this review we discuss the design cycles of
Wusheng, Liu, C Neal, Stewart
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Analog synthetic biology [PDF]
We analyse the pros and cons of analog versus digital computation in living cells. Our analysis is based on fundamental laws of noise in gene and protein expression, which set limits on the energy, time, space, molecular count and part-count resources needed to compute at a given level of precision.
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