Results 71 to 80 of about 2,683,742 (306)

Toward the first data acquisition standard in synthetic biology [PDF]

open access: yes, 2016
This paper describes the development of a new data acquisition standard for synthetic biology. This comprises the creation of a methodology that is designed to capture all the data, metadata, and protocol information associated with biopart ...
Bultelle, M   +8 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker’s yeast

open access: yesNature Communications, 2017
Filamentous fungi are a valuable source of natural therapeutic products such as antibiotics. Here the authors engineer monocellularS. cerevisiaeto perform complex secondary metabolism typical of multicellular fungi in order to demonstrate biosynthesis ...
Ali R. Awan   +6 more
doaj   +1 more source

Plant synthetic biology [PDF]

open access: yesTrends in Plant Science, 2015
Plant synthetic biology is an emerging field that combines engineering principles with plant biology toward the design and production of new devices. This emerging field should play an important role in future agriculture for traditional crop improvement, but also in enabling novel bioproduction in plants. In this review we discuss the design cycles of
Wusheng, Liu, C Neal, Stewart
openaire   +2 more sources

Cell-free protein synthesis as a prototyping platform for mammalian synthetic biology [PDF]

open access: yes, 2020
The field of mammalian synthetic biology is expanding quickly, and technologies for engineering large synthetic gene circuits are increasingly accessible. However, for mammalian cell engineering, traditional tissue culture methods are slow and cumbersome,
McClymont, David W   +9 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Advances in the heterologous biosynthesis of QS saponins: a review

open access: yesMicrobial Cell Factories
QS saponins are a type of triterpenoid glycosides derived from the bark of Quillaja saponaria (Chilean soapbark tree). They are widely used in detergents, food and cosmetics, especially as vaccine adjuvants, due to their cleansing function and ...
Yanjie Tian   +7 more
doaj   +1 more source

Phosphite synthetic auxotrophy as an effective biocontainment strategy for the industrial chassis Pseudomonas putida

open access: yesMicrobial Cell Factories, 2022
The inclusion of biosafety strategies into strain engineering pipelines is crucial for safe-by-design biobased processes. This in turn might enable a more rapid regulatory acceptance of bioengineered organisms in both industrial and environmental ...
Enrique Asin-Garcia   +5 more
doaj   +1 more source

The economics of synthetic biology

open access: yesMolecular Systems Biology, 2007
Mol Syst Biol. 3: 117 Ten years ago, genetic engineering was limited to cutting and pasting DNA from existing organisms. Today's biologists can write down gene sequences that have never existed anywhere, place an order over the Internet, and receive the desired DNA by return mail.
Henkel, Joachim, Maurer, Stephen M
openaire   +2 more sources

Composable Modular Models for Synthetic Biology. [PDF]

open access: yes, 2014
Modelling and computational simulation are crucial for the large-scale engineering of biological circuits since they allow the system under design to be simulated prior to implementation in vivo.
Misirli
core   +1 more source

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