Results 81 to 90 of about 3,570,847 (308)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Models for synthetic biology [PDF]
BMC Systems Biology, 2007 Synthetic biological engineering is emerging from biology as a distinct discipline based on quantification. The technologies propelling synthetic biology are not new, nor is the concept of designing novel biological molecules. What is new is the emphasis on system behavior.
openaire +2 more sources
Using synthetic biology to make cells tomorrow's test tubes [PDF]
, 2016 The main tenet of physical biology is that biological phenomena can be subject to the same quantitative and predictive understanding that physics has afforded in the context of inanimate matter.
Brewster, Robert C +3 more
core +1 more source
Self-healing unmanned aerial vehicle skin for icing prevention and intelligent monitoring
npj Flexible ElectronicsIn-flight icing is a common hazard in unmanned aerial vehicles (UAVs), accounting for 25% of drone accidents due to their sensitivity to weight increase.
Sijia Xu +7 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Synthetic Biology in the Press
, 2015 Synthetic biology is a rapidly evolving field which potentially can change how we live in and understand the world. Given its potential impact it is important to inform and involve the public so that it gains a proper understanding of synthetic biology ...
Stefan Eriksson +3 more
core +1 more source
Design and Reconstruction of Regulatory Parts for Fast-frowing Vibrio natriegens Synthetic Biology
, 2020 The fast-growing Vibrio natriegens is an attractive robust chassis for diverse synthetic biology applications. However, V. natriegens lacks the suitable constitutive regulatory parts for precisely tuning the gene expression and, thus, recapitulating ...
Tu, Ran +6 more
core +1 more source
Composable Modular Models for Synthetic Biology. [PDF]
, 2014 Modelling and computational simulation are crucial for the large-scale engineering of biological circuits since they allow the system under design to be simulated prior to implementation in vivo.
Misirli
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Synthetic biology platform technologies for antimicrobial applications
, 2016 The growing prevalence of antibiotic resistance calls for new approaches in the development of antimicrobial therapeutics. Likewise, improved diagnostic measures are essential in guiding the application of targeted therapies and preventing the evolution ...
Braff, Dana +5 more
core +1 more source