Results 31 to 40 of about 440,950 (267)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

A Bearing Fault Diagnosis Method Integrating the SWT and MCNN−RIME−KELM Hybrid Model

Machines
To address the issues of severe noise interference, limited classification capability of linear classifiers, and difficulty in adaptively optimizing classifier parameters in rolling bearing fault diagnosis, this paper proposes a hybrid diagnostic model ...
Liping Wang, Xing Liu, Xiaoke Su, Dongyao Zou   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Dynamic Cross-Modal Modeling with an Ultra-Lightweight Architecture for Face Anti-Spoofing

Sensors
The effectiveness of multimodal face anti-spoofing largely depends on the modeling of cross-modal relationships. However, most existing approaches rely on static fusion or implicitly learned feature aggregation, which assumes fixed modality importance ...
Nana Li, Jiayu Wang, Zuhe Li, Zhipeng Weng, Yihong Wang, Yushan Pan   +5 more
doaj   +1 more source

Light pollution affects the coastal zone of Lake Baikal

Limnological Review, 2021
The role of light pollution in aquatic ecosystems functioning has increased in recent times. In addition, the effect of such pollution has mostly been studied in coastal marine ecosystems, leaving freshwater ecosystems much less studied.
Karnaukhov Dmitry, Teplykh Maria, Dolinskaya Еkaterina, Biritskaya Sofya, Ermolaeva Yana, Pushnica Viktoria, Kuznetsova Iya, Okholina Anastasia, Bukhaeva Lidia, Silow Еugene   +9 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Multi-Scale Feature Mixing of Language Model Embeddings for Enhanced Prediction of Submitochondrial Protein Localization

Algorithms
Accurate prediction of submitochondrial localization is fundamental to understanding mitochondrial biogenesis and cellular metabolic pathways. While deep representations from pre-trained protein language models (pLMs) have significantly advanced the ...
Rong Wang, Menghua Wang, Yibo Wu, Lixiang Yang, Xiao Wang   +4 more
doaj   +1 more source

A review of the potential impacts of artificial lights on fish and wildlife and how this may apply to cannabis cultivation

California Fish and Wildlife Journal, 2020
Artificial lighting is used at cannabis cultivation sites in California to promote yield, for task lighting, and to provide security. While our understanding of how fish and wildlife respond to the artificial lights associated with cannabis cultivation
Lindsey N. Rich, Erin Ferguson, Ange Darnell Baker, Erin Chappell   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

ECE-YOLO: An Efficient Detection Model for UAV Remote Sensing Object Detection

IEEE Access
To address the challenges of drastic scale variations, dense distribution of small objects, and complex background interference in UAV remote sensing object detection, as well as the high resource consumption of existing models under high-accuracy ...
Hongjie He, Tianhang Wang, Sheng Xu, Hong Xu, Tianwen Hu, Zhongpei Sun, Jinyan Deng   +6 more
doaj   +1 more source